PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

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1RV1	CRYSTAL STRUCTURE OF HUMAN MDM2 WITH AN IMIDAZOLINE INHIBITOR 分子名称: CIS-[4,5-BIS-(4-BROMOPHENYL)-2-(2-ETHOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL]-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]METHANONE, Ubiquitin-protein ligase E3 Mdm2 著者 Lukacs, C, Kammlott, U, Graves, B. 登録日 2003-12-12 公開日 2004-01-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science, 303, 2004
1R4D	Solution structure of the chimeric L/D DNA oligonucleotide d(C8metGCGC(L)G(L)CGCG)2 分子名称: 5'-D(*CP*(8MG)P*CP*GP*(0DC)P*(0DG)P*CP*GP*CP*G)-3' 著者 Cherrak, I, Mauffret, O, Santamaria, F, Rayner, B, Hocquet, A, Ghomi, M, Fermandjian, S. 登録日 2003-10-06 公開日 2003-10-21 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 L-nucleotides and 8-methylguanine of d(C1m8G2C3G4C5LG6LC7G8C9G10)2 act cooperatively to promote a left-handed helix under physiological salt conditions. Nucleic Acids Res., 31, 2003
1RVB	MG2+ BINDING TO THE ACTIVE SITE OF ECO RV ENDONUCLEASE: A CRYSTALLOGRAPHIC STUDY OF COMPLEXES WITH SUBSTRATE AND PRODUCT DNA AT 2 ANGSTROMS RESOLUTION 分子名称: DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), MAGNESIUM ION, PROTEIN (ECO RV (E.C.3.1.21.4)) 著者 Kostrewa, D, Winkler, F.K. 登録日 1994-10-21 公開日 1995-01-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mg2+ binding to the active site of EcoRV endonuclease: a crystallographic study of complexes with substrate and product DNA at 2 A resolution. Biochemistry, 34, 1995
1RAW	ATP BINDING RNA APTAMER IN COMPLEX WITH AMP, NMR, 10 STRUCTURES 分子名称: ADENOSINE MONOPHOSPHATE, RNA APTAMER 著者 Dieckmann, T, Feigon, J. 登録日 1996-07-17 公開日 1997-01-27 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution Structure of an ATP-Binding RNA Aptamer Reveals a Novel Fold RNA, 2, 1996
1RCS	NMR STUDY OF TRP REPRESSOR-OPERATOR DNA COMPLEX 分子名称: DNA (5'-D(*CP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*TP*AP*CP*G)-3'), TRP REPRESSOR, TRYPTOPHAN 著者 Zhao, D, Zheng, Z. 登録日 1995-05-12 公開日 1996-06-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The solution structures of the trp repressor-operator DNA complex. J.Mol.Biol., 238, 1994
1R5B	Crystal structure analysis of sup35 分子名称: Eukaryotic peptide chain release factor GTP-binding subunit 著者 Kong, C, Song, H. 登録日 2003-10-10 公開日 2004-05-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe Mol.Cell, 14, 2004
1R88	The crystal structure of Mycobacterium tuberculosis MPT51 (FbpC1) 分子名称: MPT51/MPB51 antigen 著者 Wilson, R.A, Maughan, W.N, Kremer, L, Besra, G.S, Futterer, K. 登録日 2003-10-23 公開日 2003-12-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 The structure of Mycobacterium tuberculosis MPT51 (FbpC1) defines a new family of non-catalytic alpha/beta hydrolases. J.Mol.Biol., 335, 2004
1R9V	NMR Structure of a D,L-Alternating Dodecamer of Norleucine 分子名称: BOC-(D-NLE-L-NLE)4-D-NLE(METHYL)-L-NLE-D-NLE-L-NLE METHYL ESTER 著者 Navarro, E, Celda, B. 登録日 2003-10-31 公開日 2003-12-02 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of a D,L-Alternating Oligonorleucine as a Model of Beta-Helix Biopolymers, 59, 2001
1RFR	NMR structure of the 30mer stemloop-D of coxsackieviral RNA 分子名称: stemloop-D RNA of the 5'-cloverleaf of coxsackievirus B3 著者 Ohlenschlager, O, Wohnert, J, Bucci, E, Seitz, S, Hafner, S, Ramachandran, R, Zell, R, Gorlach, M. 登録日 2003-11-10 公開日 2004-03-23 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The structure of the stemloop D subdomain of coxsackievirus B3 cloverleaf RNA and its interaction with the proteinase 3C. STRUCTURE, 12, 2004
1R9W	Crystal Structure of the DNA-binding domain of the human papillomavirus type 18 (HPV-18) replication initiation protein E1 分子名称: Replication protein E1 著者 Auster, A.S, Joshua-Tor, L. 登録日 2003-10-31 公開日 2003-11-18 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The DNA-binding domain of human papillomavirus type 18 E1. Crystal structure, dimerization, and DNA binding. J.Biol.Chem., 279, 2004
1RA2	DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM) 分子名称: DIHYDROFOLATE REDUCTASE, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Sawaya, M.R, Kraut, J. 登録日 1996-10-28 公開日 1996-12-23 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RA8	DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND 2-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE 分子名称: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, DIHYDROFOLATE REDUCTASE, FOLIC ACID 著者 Sawaya, M.R, Kraut, J. 登録日 1996-11-21 公開日 1997-03-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RPN	Crystal Structure of GDP-D-mannose 4,6-dehydratase in complexes with GDP and NADPH 分子名称: GDP-mannose 4,6-dehydratase, GUANOSINE-5'-DIPHOSPHATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Webb, N.A, Mulichak, A.M, Lam, J.S, Rocchetta, H.L, Garavito, R.M. 登録日 2003-12-03 公開日 2004-02-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of a tetrameric GDP-D-mannose 4,6-dehydratase from a bacterial GDP-D-rhamnose biosynthetic pathway. Protein Sci., 13, 2004
1RRI	DHNA complex with 3-(5-amino-7-hydroxy-[1,2,3] triazolo [4,5-d]pyrimidin-2-yl)-benzoic acid 分子名称: 3-(5-AMINO-7-HYDROXY-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-2-YL)-BENZOIC ACID, Dihydroneopterin aldolase 著者 Sanders, W.J, Nienaber, V.L, Lerner, C.G, McCall, J.O, Merrick, S.M, Swanson, S.J, Harlan, J.E, Stoll, V.S, Stamper, G.F, Betz, S.F, Condroski, K.R, Meadows, R.P, Severin, J.M, Walter, K.A, Magdalinos, P, Jakob, C.G, Wagner, R, Beutel, B.A. 登録日 2003-12-08 公開日 2004-03-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization. J.Med.Chem., 47, 2004
1R2H	Human Bcl-XL containing an Ala to Leu mutation at position 142 分子名称: Apoptosis regulator Bcl-X 著者 O'Neill, J.W, Manion, M.K, Giedt, C.D, Kim, K.M, Zhang, K.Y, Hockenbery, D.M. 登録日 2003-09-26 公開日 2004-02-03 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Bcl-XL mutations suppress cellular sensitivity to antimycin A. J.Biol.Chem., 279, 2004
1R3S	Uroporphyrinogen Decarboxylase single mutant D86G in complex with coproporphyrinogen-I 分子名称: COPROPORPHYRINOGEN I, Uroporphyrinogen Decarboxylase 著者 Phillips, J.D, Whitby, F.G, Kushner, J.P, Hill, C.P. 登録日 2003-10-03 公開日 2003-12-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase Embo J., 22, 2003
1R41	Crystal structures of d(Gm5CGm5CGCGC) and d(GCGCGm5CGm5C): Effects of methylation on alternating DNA octamers 分子名称: 5'-D(*GP*CP*GP*CP*GP*(5CM)P*GP*(5CM))-3' 著者 Shi, K, Pan, B, Tippin, D, Sundaralingam, M. 登録日 2003-10-03 公開日 2003-12-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of d(Gm5)CGm5CGCGC) and d(GCGCGm5CGm5C): effects of methylation on alternating DNA octamers. Acta Crystallogr.,Sect.D, 60, 2004
1R5W	Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T-cell activation 分子名称: H-2 class II histocompatibility antigen, E-K alpha chain, MHC H2-IE-beta, ... 著者 Krogsgaard, M, Prado, N, Adams, E, He, X, Chow, D.C, Wilson, D.B, Garcia, K.C, Davis, M.M. 登録日 2003-10-13 公開日 2004-03-02 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation Mol.Cell, 12, 2003
4V5Z	Structure of a mammalian 80S ribosome obtained by docking homology models of the RNA and proteins into an 8.7 A cryo-EM map 分子名称: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S Ribosomal protein RACK1, ... 著者 Chandramouli, P, Akey, C.W. 登録日 2008-03-27 公開日 2014-07-09 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (8.7 Å) 主引用文献 Structure of the Mammalian 80S Ribosome at 8.7 A Resolution Structure, 16, 2008
4V4G	Crystal structure of five 70s ribosomes from Escherichia Coli in complex with protein Y. 分子名称: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S ribosomal protein S10, ... 著者 Vila-Sanjurjo, A, Schuwirth, B.S, Hau, C.W, Cate, J.H. 登録日 2004-10-06 公開日 2014-07-09 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (11.5 Å) 主引用文献 Structural basis for the control of translation initiation during stress. Nat.Struct.Mol.Biol., 11, 2004
4V5X	The cryo-EM structure of a 3D DNA-origami object 分子名称: SCAFFOLD STRAND,SCAFFOLD STRAND, STAPLE STRAND 著者 Bai, X.C, Martin, T.G, Scheres, S.H.W, Dietz, H. 登録日 2012-10-09 公開日 2014-07-09 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (11.5 Å) 主引用文献 Cryo-Em Structure of a 3D DNA-Origami Object. Proc.Natl.Acad.Sci.USA, 109, 2012
7CND	NCI-1 in complex with CRM1-Ran-RanBP1 分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, CRM1 isoform 1, ... 著者 Sun, Q, Lei, Y. 登録日 2020-07-31 公開日 2021-06-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-Guided Design of the First Noncovalent Small-Molecule Inhibitor of CRM1. J.Med.Chem., 64, 2021
9B00	Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with berberine analog of chloramphenicol CAM-BER, mRNA, deacylated A- and E-site tRNAphe, and deacylated P-site tRNAmet at 2.80A resolution 分子名称: 13-(2-{[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]amino}-2-oxoethyl)-9,10-dimethoxy-5,6-dihydro-2H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Batool, Z, Pavlova, J.A, Paranjpe, M.N, Tereshchenkov, A.G, Lukianov, D.A, Osterman, I.A, Bogdanov, A.A, Sumbatyan, N.V, Polikanov, Y.S. 登録日 2024-03-11 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Berberine analog of chloramphenicol exhibits a distinct mode of action and unveils ribosome plasticity. Structure, 2024
5W1W	Structure of the HLA-E-VMAPRTLVL/GF4 TCR complex 分子名称: Beta-2-microglobulin, GF4 T cell receptor alpha chain, GF4 T cell receptor beta chain, ... 著者 Gras, S, Walpole, N, Farenc, C, Rossjohn, J. 登録日 2017-06-05 公開日 2017-10-04 最終更新日 2018-01-03 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors. J. Biol. Chem., 292, 2017
6QDE	Leishmania major N-myristoyltransferase in complex with thienopyrimidine inhibitor IMP-0000877 分子名称: 3-[[6-~{tert}-butyl-2-[3-(dimethylamino)propyl-methyl-amino]thieno[3,2-d]pyrimidin-4-yl]-methyl-amino]propanenitrile, Glycylpeptide N-tetradecanoyltransferase, MAGNESIUM ION, ... 著者 Brannigan, J.A. 登録日 2019-01-01 公開日 2020-05-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Novel Thienopyrimidine Inhibitors of Leishmania N -Myristoyltransferase with On-Target Activity in Intracellular Amastigotes. J.Med.Chem., 63, 2020

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