1RPN

Crystal Structure of GDP-D-mannose 4,6-dehydratase in complexes with GDP and NADPH

Summary for 1RPN

Entry DOI	10.2210/pdb1rpn/pdb
Descriptor	GDP-mannose 4,6-dehydratase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	short-chain dehydrogenase/reductase, rossmann fold, lyase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	4
Total formula weight	156153.71
Authors	Webb, N.A.,Mulichak, A.M.,Lam, J.S.,Rocchetta, H.L.,Garavito, R.M. (deposition date: 2003-12-03, release date: 2004-02-24, Last modification date: 2023-08-23)
Primary citation	Webb, N.A.,Mulichak, A.M.,Lam, J.S.,Rocchetta, H.L.,Garavito, R.M. Crystal structure of a tetrameric GDP-D-mannose 4,6-dehydratase from a bacterial GDP-D-rhamnose biosynthetic pathway. Protein Sci., 13:529-539, 2004 Cited by PubMed: 14739333 DOI: 10.1110/ps.03393904 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation