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3H8X
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Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked host-guest system
分子名称: 5'-D(*CP*TP*GP*TP*(ME6)P*TP*(2YR)P*AP*TP*TP*GP*CP*G)-3', 5'-D(*TP*CP*GP*CP*AP*AP*TP*AP*AP*GP*AP*CP*A)-3', Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2
著者Lu, L, Yi, C, Jian, X, Zheng, G, He, C.
登録日2009-04-29
公開日2010-03-31
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system.
Nucleic Acids Res., 38, 2010
4AAE
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Crystal structure of the mutant D75N I-CreI in complex with an altered target (The four central bases, 2NN region, are composed by AGCG from 5' to 3')
分子名称: 24MER DNA, DNA ENDONUCLEASE I-CREI
著者Molina, R, Redondo, P, Stella, S, Marenchino, M, D'Abramo, M, Gervasio, F.L, Epinat, J.C, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G.
登録日2011-12-01
公開日2012-05-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
Nucleic Acids Res., 40, 2012
4AAB
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Crystal structure of the mutant D75N I-CreI in complex with its wild- type target (The four central bases, 2NN region, are composed by GTAC from 5' to 3')
分子名称: 10MER DNA 5'-D(*GP*AP*CP*GP*TP*TP*TP*TP*GP*AP)-3', 14MER DNA 5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*CP)-3', DNA ENDONUCLEASE I-CREI, ...
著者Molina, R, Redondo, P, Stella, S, Marenchino, M, D'Abramo, M, Gervasio, F.L, Epinat, J.C, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G.
登録日2011-12-01
公開日2012-05-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
Nucleic Acids Res., 40, 2012
4AAD
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Crystal structure of the mutant D75N I-CreI in complex with its wild- type target in absence of metal ions at the active site (The four central bases, 2NN region, are composed by GTAC from 5' to 3')
分子名称: 24MER DNA, DNA ENDONUCLEASE I-CREI, GLYCEROL
著者Molina, R, Redondo, P, Stella, S, Marenchino, M, D'Abramo, M, Gervasio, F.L, Epinat, J.C, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G.
登録日2011-12-01
公開日2012-05-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
Nucleic Acids Res., 40, 2012
4AAF
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BU of 4aaf by Molmil
Crystal structure of the mutant D75N I-CreI in complex with an altered target (The four central bases, 2NN region, are composed by TGCA from 5' to 3')
分子名称: 1,2-ETHANEDIOL, 24MER DNA, DNA ENDONUCLEASE I-CREI
著者Molina, R, Redondo, P, Stella, S, Marenchino, M, D'Abramo, M, Gervasio, F.L, Epinat, J.C, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G.
登録日2011-12-01
公開日2012-05-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
Nucleic Acids Res., 40, 2012
2GUI
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BU of 2gui by Molmil
Structure and Function of Cyclized Versions of the Proofreading Exonuclease Subunit of E. coli DNA Polymerase III
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA polymerase III epsilon subunit, ...
著者Park, A.Y, Carr, P.D, Ollis, D.L, Dixon, N.E.
登録日2006-04-30
公開日2007-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure and Function of Cyclized Versions of the Proofreading Exonuclease Subunit E. coli DNA Polymerase III
To be Published
2FDJ
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Crystal Structure of AlkB in complex with Fe(II) and succinate
分子名称: Alkylated DNA repair protein alkB, FE (II) ION, SUCCINIC ACID
著者Yu, B, Benach, J, Edstrom, W.C, Gibney, B.R, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2005-12-14
公開日2006-02-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB.
Nature, 439, 2006
2AY0
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BU of 2ay0 by Molmil
Structure of the Lys9Met mutant of the E. coli Proline Utilization A (PutA) DNA-binding domain.
分子名称: Bifunctional putA protein, CHLORIDE ION
著者Larson, J.D, Schuermann, J.P, Zhou, Y, Jenkins, J.L, Becker, D.F, Tanner, J.J.
登録日2005-09-06
公開日2006-08-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of the DNA-binding domain of Escherichia coli proline utilization A flavoprotein and analysis of the role of Lys9 in DNA recognition.
Protein Sci., 15, 2006
2L4L
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Structural insights into the cTAR DNA recognition by the HIV-1 Nucleocapsid protein: role of sugar deoxyriboses in the binding polarity of NC
分子名称: 5'-D(*CP*TP*GP*G)-3', HIV-1 nucleocapsid protein NCp7, ZINC ION
著者Bazzi, A, Zargarian, L, Chaminade, F, Boudier, C, De Rocquigny, H, Rene, B, Mely, Y, Fosse, P, Mauffret, O.
登録日2010-10-08
公開日2010-12-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural insights into the cTAR DNA recognition by the HIV-1 nucleocapsid protein: role of sugar deoxyriboses in the binding polarity of NC.
Nucleic Acids Res., 39, 2011
1IDX
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BU of 1idx by Molmil
Structural Basis for Poor Excision from Hairpin DNA: NMR Study
分子名称: 5'-D(*AP*GP*GP*AP*TP*CP*CP*TP*TP*UP*TP*GP*GP*AP*TP*CP*CP*T)-3'
著者Ghosh, M, Rumpal, N, Varshney, U, Chary, K.V.
登録日2001-04-05
公開日2002-05-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural basis for poor uracil excision from hairpin DNA. An NMR study.
Eur.J.Biochem., 269, 2002
2IDO
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BU of 2ido by Molmil
Structure of the E. coli Pol III epsilon-Hot proofreading complex
分子名称: 1,2-ETHANEDIOL, DNA polymerase III epsilon subunit, Hot protein, ...
著者Kirby, T.W, Harvey, S, DeRose, E.F, Chalov, S, Chikova, A.K, Perrino, F.W, Schaaper, R.M, London, R.E, Pedersen, L.C.
登録日2006-09-15
公開日2006-11-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the Escherichia coli DNA polymerase III epsilon-HOT proofreading complex.
J.Biol.Chem., 281, 2006
5BQT
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BU of 5bqt by Molmil
Structure of TrmBL2, an archaeal chromatin protein, shows a novel mode of DNA binding.
分子名称: CALCIUM ION, Putative HTH-type transcriptional regulator TrmBL2
著者Ahmad, M.U, Diederichs, K, Welte, W.
登録日2015-05-29
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Insights into Nonspecific Binding of DNA by TrmBL2, an Archaeal Chromatin Protein.
J.Mol.Biol., 427, 2015
3NX5
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BU of 3nx5 by Molmil
The crystal structure of Sanguinarine bound to DNA d(CGTACG)
分子名称: 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, 5'-D(*CP*GP*TP*AP*CP*G)-3', CALCIUM ION
著者Ferraroni, M, Bazzicalupi, C, Gratteri, P, Bilia, A.R.
登録日2010-07-13
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献X-Ray diffraction analyses of the natural isoquinoline alkaloids Berberine and Sanguinarine complexed with double helix DNA d(CGTACG)
Chem.Commun.(Camb.), 47, 2011
1XC9
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BU of 1xc9 by Molmil
Structure of a high-fidelity polymerase bound to a benzo[a]pyrene adduct that blocks replication
分子名称: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA polymerase I, DNA primer strand, ...
著者Hsu, G.W, Huang, X, Luneva, N.P, Geacintov, N.E, Beese, L.S.
登録日2004-09-01
公開日2004-12-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication
J.Biol.Chem., 280, 2005
3A1B
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BU of 3a1b by Molmil
Crystal structure of the DNMT3A ADD domain in complex with histone H3
分子名称: 1,2-ETHANEDIOL, DNA (cytosine-5)-methyltransferase 3A, Histone H3.1, ...
著者Otani, J, Arita, K, Ariyoshi, M, Shirakawa, M.
登録日2009-03-28
公開日2009-11-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.292 Å)
主引用文献Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain
Embo Rep., 10, 2009
2VBJ
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Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers
分子名称: 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP*AP*GP*GP*AP*TP*CP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP*AP*AP*AP*AP*GP*GP*CP*AP*GP*A)-3', CALCIUM ION, ...
著者Redondo, P, Prieto, J, Munoz, I.G, Alibes, A, Stricher, F, Serrano, L, Arnould, S, Perez, C, Cabaniols, J.P, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G.
登録日2007-09-14
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
7JTQ
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Human Complement Factor B Inhibited by a Slow Off-Rate Modified Aptamer of 31 Bases
分子名称: Complement factor B, DNA (32-MER)
著者Xu, X, Geisbrecht, B.V.
登録日2020-08-18
公開日2020-12-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Inhibition of the Complement Alternative Pathway by Chemically Modified DNA Aptamers That Bind with Picomolar Affinity to Factor B.
J Immunol., 206, 2021
7JTN
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Human Complement Factor B Inhibited by a Slow Off-Rate Modified Aptamer of 29 Bases
分子名称: Complement factor B, DNA (30-MER)
著者Xu, X, Geisbrecht, B.V.
登録日2020-08-18
公開日2020-12-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Inhibition of the Complement Alternative Pathway by Chemically Modified DNA Aptamers That Bind with Picomolar Affinity to Factor B.
J Immunol., 206, 2021
6HPH
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Crystal structure of human Pif1 helicase in complex with AMP-PNP
分子名称: ATP-dependent DNA helicase PIF1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Levdikov, V.M, Dehghani-Tafti, S, Bax, B.D, Sanders, C.M, Antson, A.A.
登録日2018-09-20
公開日2019-01-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase.
Nucleic Acids Res., 47, 2019
6HPU
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Crystal structure of human Pif1 helicase in complex with ADP-AlF4
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase PIF1, MAGNESIUM ION, ...
著者Levdikov, V.M, Dehghani-Tafti, S, Bax, B.D, Sanders, C.M, Antson, A.A.
登録日2018-09-21
公開日2019-01-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.96 Å)
主引用文献Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase.
Nucleic Acids Res., 47, 2019
7K72
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Structure of DNA ligase A from Mycobacterium tuberculosis bound to NAD
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, DNA ligase A, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-09-22
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of DNA ligase A from Mycobacterium tuberculosis bound to NAD
To Be Published
8CZQ
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The crystal structure of MtbTOP1 in complex with both G- and T-segments
分子名称: ACETATE ION, DNA (5'-D(*CP*TP*TP*CP*CP*GP*CP*TP*TP*GP*AP*C)-3'), DNA topoisomerase 1, ...
著者Tan, K, Tse-Dinh, Y.-C.
登録日2022-05-25
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献The interaction between transport-segment DNA and topoisomerase IA-crystal structure of MtbTOP1 in complex with both G- and T-segments.
Nucleic Acids Res., 51, 2023
6HPT
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Crystal structure of human Pif1 helicase, apoform.
分子名称: ATP-dependent DNA helicase PIF1, SULFATE ION
著者Levdikov, V.M, Dehghani-Tafti, S, Bax, B.D, Sanders, C.M, Antson, A.A.
登録日2018-09-21
公開日2019-01-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase.
Nucleic Acids Res., 47, 2019
2VE9
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Xray structure of KOPS bound gamma domain of FtsK (P. aeruginosa)
分子名称: 5'-D(*AP*CP*CP*AP*GP*GP*GP*CP*AP*GP *GP*GP*CP*GP*AP*C)-3', 5'-D(*GP*TP*CP*GP*CP*CP*CP*TP*GP*CP *CP*CP*TP*GP*GP*T)-3', DNA TRANSLOCASE FTSK, ...
著者Lowe, J, Allen, M.D, Sherratt, D.J.
登録日2007-10-17
公開日2008-09-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular Mechanism of Sequence-Directed DNA Loading and Translocation by Ftsk.
Mol.Cell, 31, 2008
2VAH
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Solution structure of a B-DNA hairpin at low pressure.
分子名称: 5'-D(*AP*GP*GP*AP*TP*CP*CP*TP*UP*TP *TP*GP*GP*AP*TP*CP*CP*T)-3'
著者Williamson, M.P, Wilton, D.J, Ghosh, M, Chary, K.V.A, Akasaka, K.
登録日2007-08-31
公開日2007-09-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Change in a B-DNA Helix with Hydrostatic Pressure
Nucleic Acids Res., 36, 2008

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