8CZQ

The crystal structure of MtbTOP1 in complex with both G- and T-segments

Summary for 8CZQ

• Entry DOI: 10.2210/pdb8czq/pdb
• Descriptor: DNA topoisomerase 1, DNA (5'-D(*CP*TP*TP*CP*CP*GP*CP*TP*TP*GP*AP*C)-3'), GLYCEROL, ... (5 entities in total)
• Functional Keywords: topoisomerase 1, mycobacterium tuberculosis, g-segment, t-segment, isomerase, isomerase-dna complex, isomerase/dna
• Biological source: Mycobacterium tuberculosis; More
• Total number of polymer chains: 4
• Total formula weight: 89699.56

Authors

Tan, K.,Tse-Dinh, Y.-C. (deposition date: 2022-05-25, release date: 2022-12-14, Last modification date: 2023-10-25)

• Primary citation: Ferdous, S.,Dasgupta, T.,Annamalai, T.,Tan, K.,Tse-Dinh, Y.C.; The interaction between transport-segment DNA and topoisomerase IA-crystal structure of MtbTOP1 in complex with both G- and T-segments.; Nucleic Acids Res., 51:349-364, 2023; PubMed: 36583363; DOI: 10.1093/nar/gkac1205

Experimental method

X-RAY DIFFRACTION (2.78 Å)