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8CZQ

The crystal structure of MtbTOP1 in complex with both G- and T-segments

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA topoisomerase 1polymer70677843.51UniProt (A0A0E8VY41)
Pfam (PF01751)
Pfam (PF01131)
Pfam (PF13368)
UniProt (by SIFTS) (P9WG49)
Mycobacterium tuberculosisDNA topoisomerase I
2B, C, D
(B, C, D)
DNA (5'-D(*CP*TP*TP*CP*CP*GP*CP*TP*TP*GP*AP*C)-3')polymer123589.33Mycobacterium tuberculosis
3E
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4F, G, H, I
(A)
ACETATE IONnon-polymer59.04Chemie (ACT)
5J, K, L, M, N...
(A, C, D)
PHOSPHATE IONnon-polymer95.08Chemie (PO4)
Sequence modifications
A: 2 - 704 (UniProt: A0A0E8VY41)
PDBExternal DatabaseDetails
Ser -1-expression tag
Asn 0-expression tag
Ala 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight88611.5
Non-Polymers*Number of molecules13
Total formula weight1088.0
All*Total formula weight89699.6
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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