PDB: 82203 件ウェブページステータス検索Chemie searchBIRD

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1S1D	Structure and protein design of human apyrase 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CALCIUM ION, ... 著者 Dai, J, Liu, J, Deng, Y, Smith, T.M, Lu, M. 登録日 2004-01-06 公開日 2004-03-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure and protein design of a human platelet function inhibitor. Cell(Cambridge,Mass.), 116, 2004
2ZXG	Aminopeptidase N complexed with the aminophosphinic inhibitor of PL250, a transition state analogue 分子名称: Aminopeptidase N, GLYCEROL, N-{(2S)-3-[(1R)-1-aminoethyl](hydroxy)phosphoryl-2-benzylpropanoyl}-L-phenylalanine, ... 著者 Nakajima, Y, Ito, K, Yoshimoto, T. 登録日 2008-12-24 公開日 2009-08-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250 Acta Crystallogr.,Sect.D, 65, 2009
8AKP	Crystal structure of the catalytic domain of G7048 from Penicillium sumatraense 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, catalytic domain of G7048 著者 Troilo, F, Scafati, V, Giovannoni, M, Mattei, B, Benedetti, M, Angelucci, F, Di Matteo, A. 登録日 2022-07-30 公開日 2022-12-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Characterization of two 1,3-beta-glucan-modifying enzymes from Penicillium sumatraense reveals new insights into 1,3-beta-glucan metabolism of fungal saprotrophs. Biotechnol Biofuels Bioprod, 15, 2022
8AX4	Crystal structure of FMV N in its RNA-free form 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nucleocapsid protein 著者 Izhaki-Tavor, L, Yechezkel, I, Dessau, M. 登録日 2022-08-30 公開日 2023-04-05 最終更新日 2023-06-28 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 RNA Encapsulation Mode and Evolutionary Insights from the Crystal Structure of Emaravirus Nucleoprotein. Microbiol Spectr, 11, 2023
8AVL	Superoxide dismutase SodFM2 from Bacteroides fragilis 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE (III) ION, Superoxide dismutase [Fe] 著者 Basle, A, Barwinska-Sendra, A, Sendra, K.M, Waldron, K. 登録日 2022-08-26 公開日 2023-04-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 An ancient metalloenzyme evolves through metal preference modulation. Nat Ecol Evol, 7, 2023
6CAI	Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 24 round 7 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Kemp Eliminase KE07 著者 Jackson, C.J, Hong, N.-S, Carr, P.D. 登録日 2018-01-30 公開日 2018-08-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9, 2018
1S18	Structure and protein design of human apyrase 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CALCIUM ION, ... 著者 Dai, J, Liu, J, Deng, Y, Smith, T.M, Lu, M. 登録日 2004-01-05 公開日 2004-03-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure and protein design of a human platelet function inhibitor. Cell(Cambridge,Mass.), 116, 2004
1BP2	STRUCTURE OF BOVINE PANCREATIC PHOSPHOLIPASE A2 AT 1.7 ANGSTROMS RESOLUTION 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, PHOSPHOLIPASE A2 著者 Dijkstra, B.W, Kalk, K.H, Hol, W.G.J, Drenth, J. 登録日 1981-04-06 公開日 1981-05-21 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of bovine pancreatic phospholipase A2 at 1.7A resolution. J.Mol.Biol., 147, 1981
8AJT	Crystal structure of the H323A mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with adenosine in the presence of K+ cations 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, Adenosylhomocysteinase, ... 著者 Drozdzal, P, Wozniak, K, Malecki, P, Gawel, M, Komorowska, M, Brzezinski, K. 登録日 2022-07-28 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.499 Å) 主引用文献 Crystal structure of the H323A mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with adenosine in the presence of K+ cations To Be Published
6WQ7	Carbonic Anhydrase II Complexed with 2-((3-Aminopropyl)(phenethyl)amino)-N-(4-fluorobenzyl)-N-(4-sulfamoylphenethyl)acetamide 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Carbonic anhydrase 2, N~2~-(3-aminopropyl)-N-[(4-fluorophenyl)methyl]-N~2~-(2-phenylethyl)-N-[2-(4-sulfamoylphenyl)ethyl]glycinamide, ... 著者 Andring, J.T, Combs, J.E, Lomelino, C, McKenna, R. 登録日 2020-04-28 公開日 2020-06-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.304 Å) 主引用文献 Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action. J.Med.Chem., 63, 2020
4NI3	Crystal Structure of GH29 family alpha-L-fucosidase from Fusarium graminearum in the closed form 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-fucosidase GH29, ... 著者 Cao, H, Walton, J.D, Brumm, P, Phillips Jr, G.N. 登録日 2013-11-05 公開日 2013-12-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.3993 Å) 主引用文献 Structure and Substrate Specificity of a Eukaryotic Fucosidase from Fusarium graminearum. J.Biol.Chem., 289, 2014
6WQ5	Carbonic Anhydrase II Complexed with 2-((3-Aminopropyl)(phenethyl)amino)-N-(furan-2-ylmethyl)-N-(4-sulfamoylphenethyl)acetamide 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Carbonic anhydrase 2, N~2~-(3-aminopropyl)-N-[(furan-2-yl)methyl]-N~2~-(2-phenylethyl)-N-[2-(4-sulfamoylphenyl)ethyl]glycinamide, ... 著者 Andring, J.T, Combs, J.E, Lomelino, C, McKenna, R. 登録日 2020-04-28 公開日 2020-06-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.304 Å) 主引用文献 Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action. J.Med.Chem., 63, 2020
4MUM	Crystal structure of mitochondrial 5'(3')-deoxy ribonucleotidase alternative spliced variant 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Pachl, P, Rezacova, P. 登録日 2013-09-22 公開日 2014-02-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.271 Å) 主引用文献 Kinetic and structural characterization of an alternatively spliced variant of human mitochondrial 5'(3')-deoxyribonucleotidase. J Enzyme Inhib Med Chem, 30, 2015
6GUR	Siderophore hydrolase EstB from Aspergillus fumigatus in complex with TAFC 分子名称: (~{Z})-5-[(1~{S},2~{S})-2-acetamido-1-oxidanyl-5-[oxidanyl(propanoyl)amino]pentoxy]-~{N},3-dimethyl-~{N}-oxidanyl-pent-2-enamide, CARBONATE ION, FE (III) ION, ... 著者 Ecker, F, Haas, H, Groll, M, Huber, E.M. 登録日 2018-06-19 公開日 2018-08-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Iron Scavenging in Aspergillus Species: Structural and Biochemical Insights into Fungal Siderophore Esterases. Angew. Chem. Int. Ed. Engl., 57, 2018
8OKN	Crystal structure of F2F-2020198-00X bound to the main protease (3CLpro/Mpro) of SARS-CoV-2. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3C-like proteinase nsp5, ... 著者 Costanzi, E, Demitri, N, Storici, P. 登録日 2023-03-28 公開日 2023-05-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination. Eur.J.Med.Chem., 253, 2023
6WFV	The crystal structure of a collagen galactosylhydroxylysyl glucosyltransferase from human 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, MANGANESE (II) ION, ... 著者 Guo, H.-F, Tsai, C.-L, Miller, M.D, Phillips Jr, G.N, Tainer, J.A, Kurie, J.M. 登録日 2020-04-04 公開日 2021-04-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The crystal structure of a collagen galactosylhydroxylysyl glucosyltransferase from human To Be Published
6WKL	Fab Fragment of Anti-human LAG3 antibody (BAP050) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAP050 Fab Heavy Chain, BAP050 Fab Light Chain 著者 Agnihotri, P, Mishra, A.K, Mariuzza, R.A. 登録日 2020-04-16 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Fab Fragment of Anti-human LAG3 antibody To Be Published
8BS8	Bovine naive ultralong antibody AbD08 collected at 100K 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Heavy chain, Light chain 著者 Clarke, J.D, Douangamath, A, Mikolajek, H, Stuart, D.I, Owens, R.J. 登録日 2022-11-24 公開日 2023-05-24 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 The impact of exchanging the light and heavy chains on the structures of bovine ultralong antibodies. Acta Crystallogr.,Sect.F, 80, 2024
4O5Q	Crystal Structure of the Alkylhydroperoxide Reductase AhpF from Escherichia coli 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alkyl hydroperoxide reductase subunit F, CADMIUM ION, ... 著者 Dip, P.V, Kamariah, N, Manimekalai, M.S.S, Balakrishna, A.M, Gruber, G. 登録日 2013-12-20 公開日 2014-11-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure, mechanism and ensemble formation of the alkylhydroperoxide reductase subunits AhpC and AhpF from Escherichia coli Acta Crystallogr.,Sect.D, 70, 2014
4MAZ	The Structure of MalL mutant enzyme V200S from Bacillus subtilus 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MAGNESIUM ION, ... 著者 Hobbs, J.K, Jiao, W, Easter, A.D, Parker, E.J, Schipper, L.A, Arcus, V.L. 登録日 2013-08-18 公開日 2013-09-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates. Acs Chem.Biol., 8, 2013
4MY0	Crystal Structure of GCN5-related N-acetyltransferase from Kribbella flavida 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYL COENZYME *A, GCN5-related N-acetyltransferase, ... 著者 Kim, Y, Mack, J, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2013-09-26 公開日 2013-11-06 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 Crystal Structure of GCN5-related N-acetyltransferase from Kribbella flavida To be Published
4NJO	crystal structure of cofactor(NAD+) bound 3-phosphoglycerate dehydrogenase in Entamoeba histolytica 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D-3-phosphoglycerate dehydrogenase, putative, ... 著者 Singh, R.K, Gourinath, S. 登録日 2013-11-11 公開日 2014-10-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Crystal structures and kinetics of Type III 3-phosphoglycerate dehydrogenase reveal catalysis by lysine. Febs J., 281, 2014
6L3M	Crystal Structure of the acyltransferase domain from the third module of the ansamitocin polyketide synthase 分子名称: 2-methoxypropanedioic acid, GLYCEROL, PHOSPHATE ION, ... 著者 Zhang, F, Zheng, J. 登録日 2019-10-11 公開日 2019-12-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structural and Biochemical Insight into the Recruitment of Acyl Carrier Protein-Linked Extender Units in Ansamitocin Biosynthesis. Chembiochem, 21, 2020
4M8U	The Structure of MalL mutant enzyme V200A from Bacillus subtilus 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ... 著者 Hobbs, J.K, Jiao, W, Easter, A.D, Parker, E.J, Schipper, L.A, Arcus, V.L. 登録日 2013-08-13 公開日 2013-09-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates. Acs Chem.Biol., 8, 2013
6ADU	Crystal structure of an enzyme in complex with ligand C 分子名称: (3~{Z})-3-(1-methylpyrrolidin-2-ylidene)indole, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... 著者 Tan, X.K, Liu, W.D, Chen, C.C, Guo, R.T. 登録日 2018-08-02 公開日 2019-08-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement. Angew.Chem.Int.Ed.Engl., 57, 2018

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