1S18

Structure and protein design of human apyrase

Summary for 1S18

• Entry DOI: 10.2210/pdb1s18/pdb
• Related: 1s1d
• Descriptor: apyrase, CALCIUM ION, ACETATE ION, ... (5 entities in total)
• Functional Keywords: adpase, five-blade beta propeller, calcium-binding protein, nucleotide-binding motif, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein: Q8WVQ1
• Total number of polymer chains: 2
• Total formula weight: 75255.69

Authors

Dai, J.,Liu, J.,Deng, Y.,Smith, T.M.,Lu, M. (deposition date: 2004-01-05, release date: 2004-03-16, Last modification date: 2024-02-14)

• Primary citation: Dai, J.,Liu, J.,Deng, Y.,Smith, T.M.,Lu, M.; Structure and protein design of a human platelet function inhibitor.; Cell(Cambridge,Mass.), 116:649-659, 2004; PubMed: 15006348; DOI: 10.1016/S0092-8674(04)00172-2

Experimental method

X-RAY DIFFRACTION (1.7 Å)