7BAQ
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3KF7
| Crystal Structure of Human p38alpha Complexed With a Triazolopyrimidine compound | 分子名称: | 3-{6-[2-(2,4-difluorophenyl)ethyl][1,2,4]triazolo[4,3-a]pyridin-3-yl}-4-methylbenzamide, Mitogen-activated protein kinase 14 | 著者 | Shieh, H.-S, Williams, J.M, Stegeman, R.A, Xing, L, Jerome, K.D. | 登録日 | 2009-10-27 | 公開日 | 2009-12-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Continued exploration of the triazolopyridine scaffold as a platform for p38 MAP kinase inhibition. Bioorg.Med.Chem.Lett., 20, 2010
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3KFI
| Major mouse urinary protein IV complexed with 2,5-dimethylpyrazine | 分子名称: | 2,5-dimethylpyrazine, CHLORIDE ION, Major urinary protein 4 | 著者 | Perez-Miller, S, Zou, Q, Hurley, T.D. | 登録日 | 2009-10-27 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones. Protein Sci., 19, 2010
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3KCN
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3KFP
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2KV4
| EGF | 分子名称: | Epidermal growth factor | 著者 | Huang, H.W, Mohan, S.K, Yu, C. | 登録日 | 2010-03-08 | 公開日 | 2011-02-23 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The NMR solution structure of human epidermal growth factor (hEGF) at physiological pH and its interactions with suramin Biochem.Biophys.Res.Commun., 402, 2010
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2KXK
| Human Insulin Mutant A22Gly-B31Lys-B32Arg | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Bocian, W, Kozerski, L. | 登録日 | 2010-05-07 | 公開日 | 2011-06-01 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Novel recombinant insulin analogue with flexible C - terminus in B chain. NMR structure of biosynthetic engineered A22G-B31K-B32R human insulin monomer in water /acetonitrile solution. To be Published
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7BAR
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3KBE
| Metal-free C. elegans Cu,Zn Superoxide Dismutase | 分子名称: | Superoxide dismutase [Cu-Zn] | 著者 | Pakhomova, O.N, Taylor, A.B, Schuermann, J.P, Culotta, V.L, Hart, P.J. | 登録日 | 2009-10-20 | 公開日 | 2010-10-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | X-ray Crystal Structure of C. elegans Cu,Zn Superoxide Dismutase To be Published
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3KBX
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3KH3
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7BB0
| Crystal structure of the cAMP-dependent protein kinase A cocrystallized with NAT22-366511 and PKI (5-24) | 分子名称: | (R)-3,3-dimethyl-5-oxo-5-(6-(3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)-1,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridin-5-yl)pentanoic acid, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha | 著者 | Oebbeke, M, Mueller, J, Glinca, S, Heine, A, Klebe, G. | 登録日 | 2020-12-16 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of the cAMP-dependent protein kinase A cocrystallized with NAT22-366511 and PKI (5-24) To Be Published
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2KXF
| Solution structure of the first two RRM domains of FBP-interacting repressor (FIR) | 分子名称: | Poly(U)-binding-splicing factor PUF60 | 著者 | Cukier, C.D, Ramos, A, Hollingworth, D, Diaz-Moreno, I, Kelly, G. | 登録日 | 2010-05-04 | 公開日 | 2010-08-18 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular basis of FIR-mediated c-myc transcriptional control. Nat.Struct.Mol.Biol., 17, 2010
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3KFG
| Major mouse urinary protein IV complexed with 2-heptanone | 分子名称: | (2S)-2-ethylhexan-1-ol, CHLORIDE ION, Major urinary protein 4, ... | 著者 | Perez-Miller, S, Zou, Q, Hurley, T.D. | 登録日 | 2009-10-27 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones. Protein Sci., 19, 2010
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3KKQ
| Crystal structure of M-Ras P40D in complex with GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein M-Ras | 著者 | Muraoka, S, Shima, F, Liao, J, Ijiri, Y, Matsumoto, K, Ye, M, Inoue, T, Kataoka, T. | 登録日 | 2009-11-06 | 公開日 | 2010-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural basis for conformational dynamics of GTP-bound Ras protein J.Biol.Chem., 285, 2010
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3KHV
| Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol | 分子名称: | SULFATE ION, TRIETHYLENE GLYCOL, Urokinase-type plasminogen activator, ... | 著者 | Jiang, L.-G, Zhao, G.-X, Bian, X.-B, Yuan, C, Huang, Z.-X, Huang, M.-D. | 登録日 | 2009-10-30 | 公開日 | 2009-12-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol CHIN.J.STRUCT.CHEM., 28, 2009
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3KB7
| Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor | 分子名称: | 8-{[2-methoxy-5-(4-methylpiperazin-1-yl)phenyl]amino}-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide, L(+)-TARTARIC ACID, Serine/threonine-protein kinase PLK1, ... | 著者 | Bossi, R.T, Bertrand, J.A. | 登録日 | 2009-10-20 | 公開日 | 2010-05-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors J.Med.Chem., 53, 2010
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3KKV
| Structure of PKA with a protein Kinase B-selective inhibitor. | 分子名称: | (2S)-1-{[6-furan-3-yl-5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxy}-3-(1H-indol-3-yl)propan-2-amine, PKI kinase inhibitor, cAMP-dependent protein kinase catalytic subunit alpha | 著者 | Elkins, P.A, Concha, N.O. | 登録日 | 2009-11-06 | 公開日 | 2010-12-22 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of PKA with a protein Kinase B-selective inhibitor. To be Published
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2KV3
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2KXD
| The structure of SH3-F2 | 分子名称: | 11-mer peptide,Spectrin alpha chain, non-erythrocytic 1,Spectrin alpha chain, non-erythrocytic 1 | 著者 | Kutyshenko, V.P, Gushchina, L.V, Khristoforov, V.S, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, I.u.A, Fedyukina, D.V, Filimonov, V.V. | 登録日 | 2010-04-30 | 公開日 | 2011-04-20 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure and dynamics of the chimeric protein SH3-F2 Mol.Biol.(Engl.Transl.), 44, 2010
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2KXN
| NMR structure of human Tra2beta1 RRM in complex with AAGAAC RNA | 分子名称: | 5'-R(*AP*AP*GP*AP*AP*C)-3', Transformer-2 protein homolog beta | 著者 | Clery, A, Jayne, S, Benderska, N, Dominguez, C, Stamm, S, Allain, F.H.-T. | 登録日 | 2010-05-10 | 公開日 | 2011-03-16 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-beta1 Nat.Struct.Mol.Biol., 18, 2011
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3KFF
| Major mouse urinary protein IV complexed with 2-sec-butyl-4,5-dihydrothiazole | 分子名称: | 2-[(1R)-1-methylpropyl]-4,5-dihydro-1,3-thiazole, 2-[(1S)-1-methylpropyl]-4,5-dihydro-1,3-thiazole, CHLORIDE ION, ... | 著者 | Perez-Miller, S, Zou, Q, Hurley, T.D. | 登録日 | 2009-10-27 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | 主引用文献 | High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones. Protein Sci., 19, 2010
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7BKW
| Endothiapepsin structure obtained at 100K with fragment BTB09871 bound | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | 著者 | Engilberge, S, Huang, C.-Y, Smith, K.M.L, Eris, D, Marsh, M, Wang, M, Wojdyla, J.A. | 登録日 | 2021-01-17 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Endothiapepsin structure obtained at 100K with fragment BTB09871 bound To Be Published
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2KGT
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2KM8
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