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3KKV

Structure of PKA with a protein Kinase B-selective inhibitor.

Summary for 3KKV
Entry DOI10.2210/pdb3kkv/pdb
DescriptorcAMP-dependent protein kinase catalytic subunit alpha, PKI kinase inhibitor, (2S)-1-{[6-furan-3-yl-5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxy}-3-(1H-indol-3-yl)propan-2-amine, ... (4 entities in total)
Functional Keywordsprotein kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceBos taurus (bovine)
More
Cellular locationCytoplasm : P00517
Total number of polymer chains2
Total formula weight43476.34
Authors
Elkins, P.A.,Concha, N.O. (deposition date: 2009-11-06, release date: 2010-12-22, Last modification date: 2014-12-10)
Primary citationLin, H.,Elkins, P.A.,Concha, N.O.,Heerding, D.,Wang, W.,Nidarmarthy, S.,Luengo, J.I.,Nelson, R.,Knick, V.B.,Choudhry, A.E.
Structure of PKA with a protein Kinase B-selective inhibitor.
To be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

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