7BAQ
Crystal structure of the cAMP-dependent protein kinase A cocrystallized with a chiral ligand (S- and E-configuration) and PKI (5-24)
Summary for 7BAQ
Entry DOI | 10.2210/pdb7baq/pdb |
Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, (S,E)-3-(2-(3-bromo-4-hydroxybenzylidene)hydrazineyl)-2-(3-chlorophenyl)-3-oxopropan-1-aminium, ... (4 entities in total) |
Functional Keywords | phosphotransferase, signalling pathways, glycogen metabolism, serine/threonine kinase, transferase |
Biological source | Cricetulus griseus (Chinese hamster) More |
Total number of polymer chains | 2 |
Total formula weight | 43403.63 |
Authors | Oebbeke, M.,Heine, A.,Klebe, G. (deposition date: 2020-12-16, release date: 2022-01-12, Last modification date: 2024-01-31) |
Primary citation | Oebbeke, M.,Koester, H.,Brass, S.,Gerber, H.-D.,Heine, A.,Klebe, G. Crystal structure of the cAMP-dependent protein kinase A cocrystallized with a chiral ligand (S- and E-configuration) and PKI (5-24) To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.54 Å) |
Structure validation
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