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7BB0

Crystal structure of the cAMP-dependent protein kinase A cocrystallized with NAT22-366511 and PKI (5-24)

Summary for 7BB0
Entry DOI10.2210/pdb7bb0/pdb
DescriptorcAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, (R)-3,3-dimethyl-5-oxo-5-(6-(3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)-1,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridin-5-yl)pentanoic acid, ... (4 entities in total)
Functional Keywordsphosphotransferase, signalling pathways, glycogen metabolism, serine/threonine kinase, transferase
Biological sourceCricetulus griseus (Chinese hamster)
More
Total number of polymer chains2
Total formula weight43750.60
Authors
Oebbeke, M.,Mueller, J.,Glinca, S.,Heine, A.,Klebe, G. (deposition date: 2020-12-16, release date: 2022-01-12, Last modification date: 2024-01-31)
Primary citationOebbeke, M.,Mueller, J.,Heine, A.,Klebe, G.
Crystal structure of the cAMP-dependent protein kinase A cocrystallized with NAT22-366511 and PKI (5-24)
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

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