7BAR

Crystal structure of the cAMP-dependent protein kinase A with a chiral ligand (S- and E-configuration, soaked)

Summary for 7BAR

• Entry DOI: 10.2210/pdb7bar/pdb
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, (S,E)-3-(2-(3-bromo-4-hydroxybenzylidene)hydrazineyl)-2-(3-chlorophenyl)-3-oxopropan-1-aminium (3 entities in total)
• Functional Keywords: phosphotransferase, signalling pathways, glycogen metabolism, serine/threonine kinase, transferase
• Biological source: Cricetulus griseus (Chinese hamster)
• Total number of polymer chains: 1
• Total formula weight: 41510.43

Authors

Oebbeke, M.,Heine, A.,Klebe, G. (deposition date: 2020-12-16, release date: 2022-01-12, Last modification date: 2024-11-20)

• Primary citation: Oebbeke, M.,Koester, H.,Brass, S.,Gerber, H.-D.,Heine, A.,Klebe, G.; Crystal structure of the cAMP-dependent protein kinase A with a chiral ligand (S- and E-configuration, soaked); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.37 Å)