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1C74
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Structure of the double mutant (K53,56M) of phospholipase A2
分子名称: CALCIUM ION, PHOSPHOLIPASE A2
著者Sekar, K, Tsai, M.D, Jain, M.K, Ramakumar, S.
登録日2000-01-22
公開日2000-07-22
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of the anionic interface preference and k*cat activation of pancreatic phospholipase A2.
Biochemistry, 39, 2000
6CN5
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BU of 6cn5 by Molmil
HUMAN RETENOID-RELATED ORPHAN RECEPTOR-GAMMA LIGAND- BINDING DOMAIN IN COMPLEX WITH INDOLE LIGAND CP9b IN INVERSE AGONIST CONFORMATION
分子名称: 4-cyano-N-{3-[1-(cyclohexanecarbonyl)piperidin-4-yl]-1-methyl-1H-indol-5-yl}pyridine-2-carboxamide, Nuclear receptor ROR-gamma
著者Kauppi, B, Vajdos, F.
登録日2018-03-07
公開日2018-09-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist.
J. Med. Chem., 61, 2018
2MSK
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BU of 2msk by Molmil
Solution Structure and Chemical Shift Assignments for BeF3 activated Receiver Domain of Nitrogen Regulatory Protein C (NtrC) at 35C
分子名称: Nitrogen regulation protein NR(I)
著者Clarkson, M.W, Pontiggia, F, Villali, J, Kern, D.
登録日2014-08-04
公開日2015-07-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Free energy landscape of activation in a signalling protein at atomic resolution.
Nat Commun, 6, 2015
1KO7
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BU of 1ko7 by Molmil
X-ray structure of the HPr kinase/phosphatase from Staphylococcus xylosus at 1.95 A resolution
分子名称: Hpr kinase/phosphatase, PHOSPHATE ION
著者Marquez, J.A, Hasenbein, S, Koch, B, Fieulaine, S, Nessler, S, Hengstenberg, W, Scheffzek, K.
登録日2001-12-20
公開日2002-04-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of the full-length HPr kinase/phosphatase from Staphylococcus xylosus at 1.95 A resolution: Mimicking the product/substrate of the phospho transfer reactions.
Proc.Natl.Acad.Sci.USA, 99, 2002
5SVA
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BU of 5sva by Molmil
Mediator-RNA Polymerase II Pre-Initiation Complex
分子名称: 108bp HIS4 Promoter Non-template Strand (-92/+16), 108bp HIS4 Promoter Template Strand (+16/-92), DNA repair helicase RAD25, ...
著者Robinson, P.J, Bushnell, D.A, Kornberg, R.D.
登録日2016-08-05
公開日2016-09-28
最終更新日2019-11-27
実験手法ELECTRON MICROSCOPY (15.3 Å)
主引用文献Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
Cell, 166, 2016
1KO2
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VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa with an oxidized Cys (cysteinesulfonic)
分子名称: ACETATE ION, VIM-2 metallo-beta-lactamase, ZINC ION
著者Garcia-Saez, I, Docquier, J.-D, Rossolini, G.M, Dideberg, O.
登録日2001-12-20
公開日2003-09-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The three-dimensional structure of VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form
J.Mol.Biol., 375, 2008
1KV0
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Cis/trans Isomerization of Non-prolyl Peptide Bond Observed in Crystal Structure of an Scorpion Toxin
分子名称: Alpha-like toxin BmK-M7
著者Guan, R.J, He, X.L, Wang, M, Xiang, Y, Wang, D.C.
登録日2002-01-23
公開日2003-09-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural mechanism governing cis and trans isomeric states and an intramolecular switch for cis/trans isomerization of a non-proline peptide bond observed in crystal structures of scorpion toxins.
J.Mol.Biol., 341, 2004
1KX0
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Rat mannose protein A (H189V I207V) complexed with man-a13-man
分子名称: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN A, ...
著者Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I.
登録日2002-01-30
公開日2002-07-05
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
2JC5
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Apurinic Apyrimidinic (AP) endonuclease (NApe) from Neisseria Meningitidis
分子名称: 1,4-DIETHYLENE DIOXIDE, BICINE, EXODEOXYRIBONUCLEASE, ...
著者Carpenter, E.P, Corbett, A, Thomson, H, Adacha, J, Jensen, K, Bergeron, J, Kasampalidis, I, Exley, R, Winterbotham, M, Tang, C, Baldwin, G.S, Freemont, P.
登録日2006-12-19
公開日2007-03-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
Embo J., 26, 2007
8E7X
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RsTSPO A138F with one Heme bound
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan-rich sensory protein
著者Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S.
登録日2022-08-25
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity.
Biochemistry, 62, 2023
2JK9
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BU of 2jk9 by Molmil
The structure of splA-ryanodine receptor domain and SOCS box containing 1 in complex with a PAR-4 peptide
分子名称: PRKC APOPTOSIS WT1 REGULATOR PROTEIN, SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 1
著者Filippakopoulos, P, Bullock, A, Keates, T, Savitsky, P, Murray, J.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Wickstroem, M, Bountra, C, Knapp, S.
登録日2008-08-22
公開日2008-09-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural Basis for Par-4 Recognition by the Spry Domain-and Socs Box-Containing Proteins Spsb1, Spsb2, and Spsb4.
J.Mol.Biol., 401, 2010
2JC4
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BU of 2jc4 by Molmil
3'-5' exonuclease (NExo) from Neisseria Meningitidis
分子名称: ACETATE ION, DIHYDROGENPHOSPHATE ION, EXODEOXYRIBONUCLEASE III, ...
著者Carpenter, E.P, Corbett, A, Thomson, H, Adacha, J, Jensen, K, Bergeron, J, Kasampalidis, I, Exley, R, Winterbotham, M, Tang, C, Baldwin, G, Freemont, P.
登録日2006-12-19
公開日2007-03-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
Embo J., 26, 2007
8E7Z
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RsTSPO mutant -A138F
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Tryptophan-rich sensory protein
著者Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S.
登録日2022-08-25
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity.
Biochemistry, 62, 2023
1KWZ
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BU of 1kwz by Molmil
Rat mannose protein A (H189V) complexed with Man-a13-Man
分子名称: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN A, ...
著者Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I.
登録日2002-01-30
公開日2002-07-05
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
1ASH
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BU of 1ash by Molmil
THE STRUCTURE OF ASCARIS HEMOGLOBIN DOMAIN I AT 2.2 ANGSTROMS RESOLUTION: MOLECULAR FEATURES OF OXYGEN AVIDITY
分子名称: HEMOGLOBIN (OXY), OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE
著者Yang, J, Mathews, F.S, Kloek, A.P, Goldberg, D.E.
登録日1995-01-06
公開日1995-02-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The structure of Ascaris hemoglobin domain I at 2.2 A resolution: molecular features of oxygen avidity.
Proc.Natl.Acad.Sci.USA, 92, 1995
1KWV
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Rat mannose binding protein A complexed with a-Me-GlcNAc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I.
登録日2002-01-30
公開日2002-07-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
1K2E
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BU of 1k2e by Molmil
crystal structure of a nudix protein from Pyrobaculum aerophilum
分子名称: ACETIC ACID, GLYCEROL, NICKEL (II) ION, ...
著者Wang, S, Mura, C, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2001-09-26
公開日2002-04-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets.
Acta Crystallogr.,Sect.D, 58, 2002
1JER
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BU of 1jer by Molmil
CUCUMBER STELLACYANIN, CU2+, PH 7.0
分子名称: COPPER (II) ION, CUCUMBER STELLACYANIN
著者Hart, P.J, Nersissian, A.M, Herrmann, R.G, Nalbandyan, R.M, Valentine, J.S, Eisenberg, D.
登録日1996-08-21
公開日1997-02-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A missing link in cupredoxins: crystal structure of cucumber stellacyanin at 1.6 A resolution.
Protein Sci., 5, 1996
1B4T
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BU of 1b4t by Molmil
H48C YEAST CU(II)/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE
分子名称: CHLORIDE ION, COPPER (II) ION, PROTEIN (CU/ZN SUPEROXIDE DISMUTASE), ...
著者Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D.
登録日1998-12-23
公開日1999-12-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structure-based mechanism for copper-zinc superoxide dismutase.
Biochemistry, 38, 1999
1JN1
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Structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Haemophilus influenzae (HI0671)
分子名称: 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE, COBALT (II) ION, SULFATE ION
著者Lehmann, C, Lim, K, Toedt, J, Krajewski, W, Howard, A, Eisenstein, E, Herzberg, O, Structure 2 Function Project (S2F)
登録日2001-07-21
公開日2002-08-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of 2C-methyl-D-erythrol-2,4-cyclodiphosphate synthase from Haemophilus influenzae: activation by conformational transition.
Proteins, 49, 2002
1B4L
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BU of 1b4l by Molmil
15 ATMOSPHERE OXYGEN YEAST CU/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE
分子名称: COPPER (II) ION, PROTEIN (CU/ZN SUPEROXIDE DISMUTASE), ZINC ION
著者Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D.
登録日1998-12-22
公開日1999-12-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structure-based mechanism for copper-zinc superoxide dismutase.
Biochemistry, 38, 1999
1KWY
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BU of 1kwy by Molmil
Rat mannose protein A complexed with man-a13-man.
分子名称: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN A, ...
著者Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I.
登録日2002-01-30
公開日2002-07-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
1BXE
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BU of 1bxe by Molmil
RIBOSOMAL PROTEIN L22 FROM THERMUS THERMOPHILUS
分子名称: CHLORIDE ION, PROTEIN (RIBOSOMAL PROTEIN L22)
著者Unge, J, Aberg, A, Al-Karadaghi, S, Nikulin, A, Nikonov, S, Davydova, N, Nevskaya, N, Garber, M, Liljas, A.
登録日1998-10-02
公開日1998-10-07
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of ribosomal protein L22 from Thermus thermophilus: insights into the mechanism of erythromycin resistance.
Structure, 6, 1998
2K9J
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BU of 2k9j by Molmil
Integrin alphaIIb-beta3 transmembrane complex
分子名称: Integrin alpha-IIb light chain, Integrin beta-3
著者Lau, T, Kim, C, Ginsberg, M.H, Ulmer, T.S.
登録日2008-10-15
公開日2009-03-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling
Embo J., 28, 2009
1KGO
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BU of 1kgo by Molmil
R2F from Corynebacterium Ammoniagenes in its reduced, Fe containing, form
分子名称: FE (II) ION, Ribonucleotide reductase protein R2F
著者Hogbom, M, Huque, Y, Sjoberg, B.M, Nordlund, P.
登録日2001-11-28
公開日2001-12-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of the di-iron/radical protein of ribonucleotide reductase from Corynebacterium ammoniagenes.
Biochemistry, 41, 2002

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