1C74

Structure of the double mutant (K53,56M) of phospholipase A2

Summary for 1C74

Related1MKT
DescriptorPHOSPHOLIPASE A2, CALCIUM ION (3 entities in total)
Functional Keywordsalpha helix, beta sheet, double mutant, hydrolase
Biological sourceBos taurus (cattle)
Cellular locationSecreted P00593
Total number of polymer chains1
Total molecular weight13854.61
Authors
Sekar, K.,Tsai, M.D.,Jain, M.K.,Ramakumar, S. (deposition date: 2000-01-22, release date: 2000-07-22, Last modification date: 2011-07-13)
Primary citation
Yu, B.Z.,Poi, M.J.,Ramagopal, U.A.,Jain, R.,Ramakumar, S.,Berg, O.G.,Tsai, M.D.,Sekar, K.,Jain, M.K.
Structural basis of the anionic interface preference and k*cat activation of pancreatic phospholipase A2.
Biochemistry, 39:12312-12323, 2000
PubMed: 11015210 (PDB entries with the same primary citation)
DOI: 10.1021/bi000740k
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.20370.8%6.3%4.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload