3E7K
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4FVS
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3E7W
| Crystal structure of DLTA: Implications for the reaction mechanism of non-ribosomal peptide synthetase (NRPS) adenylation domains | 分子名称: | ADENOSINE MONOPHOSPHATE, D-alanine--poly(phosphoribitol) ligase subunit 1, PHOSPHATE ION | 著者 | Yonus, H, Neumann, P, Zimmermann, S, May, J.J, Marahiel, M.A, Stubbs, M.T. | 登録日 | 2008-08-19 | 公開日 | 2008-09-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Crystal structure of DltA. Implications for the reaction mechanism of non-ribosomal peptide synthetase adenylation domains J.Biol.Chem., 283, 2008
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4FWS
| Crystal structure of Salmonella typhimurium propionate kinase (TdcD) in complex with CTP | 分子名称: | 1,2-ETHANEDIOL, CYTIDINE-5'-TRIPHOSPHATE, Propionate kinase | 著者 | Chittori, S, Savithri, H.S, Murthy, M.R.N. | 登録日 | 2012-07-01 | 公開日 | 2013-06-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Mechanistic features of Salmonella typhimurium propionate kinase (TdcD): insights from kinetic and crystallographic studies. Biochim.Biophys.Acta, 1834, 2013
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3E5I
| Carbonmonoxy Sperm Whale Myoglobin at 120 K: Laser off | 分子名称: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S. | 登録日 | 2008-08-14 | 公開日 | 2009-02-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin Proc.Natl.Acad.Sci.USA, 106, 2009
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3R8C
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3E5S
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4FXI
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4GAI
| Crystal structure of EBI-005, a chimera of human IL-1beta and IL-1Ra | 分子名称: | EBI-005 | 著者 | Hou, J, Townson, S.A, Kovalchin, J.T, Masci, A, Kiner, O, Shu, Y, King, B, Thomas, C, Garcia, K.C, Furfine, E.S, Barnes, T.M. | 登録日 | 2012-07-25 | 公開日 | 2013-02-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Design of a superior cytokine antagonist for topical ophthalmic use. Proc.Natl.Acad.Sci.USA, 110, 2013
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3ROQ
| Crystal structure of human CD38 in complex with compound CZ-46 | 分子名称: | (2R,3R,4S,5S)-4-fluoro-3,5-dihydroxytetrahydrofuran-2-yl 2-phenylethyl hydrogen (S)-phosphate, ADP-ribosyl cyclase 1 | 著者 | Zhang, H, Lee, H.C, Hao, Q. | 登録日 | 2011-04-26 | 公開日 | 2011-12-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Catalysis-based inhibitors of the calcium signaling function of CD38. Biochemistry, 51, 2012
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3RS0
| H-Ras soaked in neat cyclopentanol: one of 10 in MSCS set | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Mattos, C, Buhrman, G, Kearney, B. | 登録日 | 2011-05-02 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Analysis of Binding Site Hot Spots on the Surface of Ras GTPase. J.Mol.Biol., 413, 2011
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4GEV
| E. coli thymidylate synthase Y209W variant in complex with substrate and a cofactor analog | 分子名称: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-deoxy-5'-uridylic acid, Thymidylate synthase | 著者 | Newby, Z, Lee, T.T, Finer-Moore, J, Stroud, R.M. | 登録日 | 2012-08-02 | 公開日 | 2012-08-29 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | A remote mutation affects the hydride transfer by disrupting concerted protein motions in thymidylate synthase. J.Am.Chem.Soc., 134, 2012
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4GGA
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4GIE
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4GIP
| Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 (PIV5) fusion protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1, Fusion glycoprotein F2 | 著者 | Welch, B.D, Liu, Y, Kors, C.A, Leser, G.P, Jardetzky, T.S, Lamb, R.A. | 登録日 | 2012-08-08 | 公開日 | 2012-09-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein. Proc.Natl.Acad.Sci.USA, 109, 2012
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3EF6
| Crystal structure of Toluene 2,3-Dioxygenase Reductase | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, SULFATE ION, ... | 著者 | Friemann, R, Lee, K, Brown, E.N, Gibson, D.T, Eklund, H, Ramaswamy, S. | 登録日 | 2008-09-08 | 公開日 | 2009-03-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structures of the multicomponent Rieske non-heme iron toluene 2,3-dioxygenase enzyme system Acta Crystallogr.,Sect.D, 65, 2009
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3EGA
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3ROM
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2IAY
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4FU3
| CID of human RPRD1B | 分子名称: | CHLORIDE ION, Regulation of nuclear pre-mRNA domain-containing protein 1B, UNKNOWN ATOM OR ION | 著者 | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | 登録日 | 2012-06-28 | 公開日 | 2012-08-29 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | CID of human RPRD1B TO BE PUBLISHED
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3RS2
| H-Ras soaked in 50% 2,2,2-trifluoroethanol: one of 10 in MSCS set | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Mattos, C, Buhrman, G, Kearney, B. | 登録日 | 2011-05-02 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.836 Å) | 主引用文献 | Analysis of Binding Site Hot Spots on the Surface of Ras GTPase. J.Mol.Biol., 413, 2011
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3ERO
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3RV1
| Crystal structure of the N-terminal and RNase III domains of K. polysporus Dcr1 E224Q mutant | 分子名称: | K. polysporus Dcr1 | 著者 | Nakanishi, K, Weinberg, D.E, Bartel, D.P, Patel, D.J. | 登録日 | 2011-05-05 | 公開日 | 2011-08-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.975 Å) | 主引用文献 | The inside-out mechanism of dicers from budding yeasts. Cell(Cambridge,Mass.), 146, 2011
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3EN6
| Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP102, a multitargeted kinase inhibitor | 分子名称: | 1-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src | 著者 | Blair, J.A, Apsel, B, Knight, Z.A, Shokat, K.M. | 登録日 | 2008-09-25 | 公開日 | 2008-10-14 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat.Chem.Biol., 4, 2008
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3E3A
| The Structure of Rv0554 from Mycobacterium tuberculosis | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, POSSIBLE PEROXIDASE BPOC | 著者 | Johnston, J.M, Baker, E.N. | 登録日 | 2008-08-06 | 公開日 | 2009-06-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis. Acta Crystallogr.,Sect.D, 66, 2010
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