PDB: 1345 件ウェブページステータス検索Chemie searchBIRD

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5JHG	Crystal structure of the complex between the human RhoA and the DH/PH domain of human ARHGEF11 分子名称: GLYCEROL, Rho guanine nucleotide exchange factor 11, Transforming protein RhoA 著者 Wang, R, Chen, Q, Zhang, H, Yan, Z, Li, J, Miao, L, Wang, F. 登録日 2016-04-21 公開日 2017-04-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and ARHGEF11 To Be Published
5JCZ	Rab11 bound to MyoVa-GTD 分子名称: 1,2-ETHANEDIOL, ACETATE ION, BERYLLIUM TRIFLUORIDE ION, ... 著者 Pylypenko, O, Attanda, W, Gauquelin, C, Malherbes, G, Houdusse, A. 登録日 2016-04-15 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.056 Å) 主引用文献 Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes. Elife, 5, 2016
5LDD	Crystal structure of the heterodimeric GEF Mon1-Ccz1 in complex with Ypt7 分子名称: Ccz1, Mon1, Rab small monomeric GTPase-like protein, ... 著者 Kiontke, S, Kuemmel, D. 登録日 2016-06-24 公開日 2017-01-18 最終更新日 2018-03-14 実験手法 X-RAY DIFFRACTION (2.496 Å) 主引用文献 Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1-Ccz1. Nat Commun, 8, 2017
5LPN	Structure of human Rab10 in complex with the bMERB domain of Mical-1 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein-methionine sulfoxide oxidase MICAL1, ... 著者 Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Mueller, M.P, Gazdag, E.M. 登録日 2016-08-14 公開日 2016-08-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 bMERB domains are bivalent Rab8 family effectors evolved by gene duplication. Elife, 5, 2016
4QXA	Crystal structure of the Rab9A-RUTBC2 RBD complex 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-9A, ... 著者 Zhang, Z, Wang, S, Ding, J. 登録日 2014-07-19 公開日 2014-09-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the Rab9A-RUTBC2 RBD complex reveals the molecular basis for the binding specificity of Rab9A with RUTBC2. Structure, 22, 2014
4UJ4	Crystal structure of human Rab11-Rabin8-FIP3 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab-3A-interacting protein, ... 著者 Vetter, M, Lorentzen, E. 登録日 2015-04-08 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11. Nat. Struct. Mol. Biol., 22, 2015
4UJ3	Crystal structure of human Rab11-Rabin8-FIP3 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RAB-3A-INTERACTING PROTEIN, ... 著者 Vetter, M, Lorentzen, E. 登録日 2015-04-08 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of Rab11-Fip3-Rabin8 Reveals Simultaneous Binding of Fip3 and Rabin8 Effectors to Rab11. Nat.Struct.Mol.Biol., 22, 2015
4DVG	Crystal structure of E. histolytica Formin1 bound to EhRho1-GTPgammaS 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Diaphanous protein, MAGNESIUM ION, ... 著者 Bosch, D.E, Siderovski, D.P. 登録日 2012-02-23 公開日 2012-11-14 最終更新日 2012-11-28 実験手法 X-RAY DIFFRACTION (2.604 Å) 主引用文献 Entamoeba histolytica Rho1 Regulates Actin Polymerization through a Divergent, Diaphanous-Related Formin. Biochemistry, 51, 2012
5FI1	Crystal Structure of the P-Rex1 DH/PH tandem in complex with Cdc42 分子名称: Cell division control protein 42 homolog, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein,Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein 著者 Cash, J.N, Tesmer, J.J.G. 登録日 2015-12-22 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.203 Å) 主引用文献 Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3. Structure, 24, 2016
5FBR	PI4KB in complex with Rab11 and the MI359 Inhibitor 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... 著者 Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. 登録日 2015-12-14 公開日 2016-12-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.28 Å) 主引用文献 PI4KB in complex with Rab11 and the MI359 Inhibitor To Be Published
5FBQ	PI4KB in complex with Rab11 and the MI358 Inhibitor 分子名称: GUANOSINE-5'-DIPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... 著者 Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. 登録日 2015-12-14 公開日 2016-12-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.789 Å) 主引用文献 PI4KB in complex with Rab11 and the MI358 Inhibitor To Be Published
5HPY	Crystal Structure of RhoA.GDP.MgF3-in complex with human Myosin 9b RhoGAP domain 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRIFLUOROMAGNESATE, ... 著者 Yi, F.S, Ren, J.Q, Feng, W. 登録日 2016-01-21 公開日 2016-07-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism J.Mol.Biol., 428, 2016
5HZH	Crystal structure of photoinhibitable Rac1 containing C450A mutant LOV2 domain 分子名称: CALCIUM ION, FLAVIN MONONUCLEOTIDE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Tarnawski, M, Dagliyan, O, Chu, P.H, Shirvanyants, D, Dokholyan, N.V, Hahn, K.M, Schlichting, I. 登録日 2016-02-02 公開日 2016-12-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Engineering extrinsic disorder to control protein activity in living cells. Science, 354, 2016
5FR2	Farnesylated RhoA-GDP in complex with RhoGDI-alpha, lysine acetylated at K178 分子名称: FARNESYL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Kuhlmann, N, Wroblowski, S, Knyphausen, P, de Boor, S, Brenig, J, Zienert, A.Y, Meyer-Teschendorf, K, Praefcke, G.J.K, Nolte, H, Krueger, M, Schacherl, M, Baumann, U, James, L.C, Chin, J.W, Lammers, M. 登録日 2015-12-15 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Structural and Mechanistic Insights Into the Regulation of the Fundamental Rho-Regulator Rhogdi Alpha by Lysine Acetylation. J.Biol.Chem., 291, 2016
5FBL	PI4KB in complex with Rab11 and the MI356 Inhibitor 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... 著者 Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. 登録日 2015-12-14 公開日 2016-12-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.372 Å) 主引用文献 PI4KB in complex with Rab11 and the MI356 Inhibitor To Be Published
5FBV	PI4KB in complex with Rab11 and the MI364 Inhibitor 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... 著者 Chalupska, D, Mejdrova, I, Nencka, R, Boura, E. 登録日 2015-12-14 公開日 2016-12-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.285 Å) 主引用文献 PI4KB in complex with Rab11 and the MI364 Inhibitor To Be Published
5FR1	Double acetylated RhoGDI-alpha in complex with RhoA-GDP 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RHO GDP-DISSOCIATION INHIBITOR 1, ... 著者 Kuhlmann, N, Wroblowski, S, Lammers, M. 登録日 2015-12-15 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Rhogdi Alpha Acetylation at K127 and K141 Affects Binding Towards Non-Prenylated Rhoa. Biochemistry, 55, 2016
5FI0	Crystal Structure of the P-Rex1 DH/PH tandem in complex with Rac1 分子名称: PHOSPHATE ION, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein,Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, Ras-related C3 botulinum toxin substrate 1 著者 Cash, J.N, Tesmer, J.J.G. 登録日 2015-12-22 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.282 Å) 主引用文献 Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3. Structure, 24, 2016
5IRC	p190A GAP domain complex with RhoA 分子名称: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Derewenda, U, Derewenda, Z. 登録日 2016-03-12 公開日 2016-08-17 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS. J.Biol.Chem., 291, 2016
4XH9	CRYSTAL STRUCTURE OF HUMAN RHOA IN COMPLEX WITH DH/PH FRAGMENT OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR NET1 分子名称: Neuroepithelial cell-transforming gene 1 protein, Transforming protein RhoA 著者 Garcia, C, Petit, P, Boutin, J.A, Ferry, G, Vuillard, L. 登録日 2015-01-05 公開日 2015-01-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A structural study of the complex between neuroepithelial cell transforming gene 1 (Net1) and RhoA reveals a potential anticancer drug hot spot. J. Biol. Chem., 293, 2018
4XOI	Structure of hsAnillin bound with RhoA(Q63L) at 2.1 Angstroms resolution 分子名称: Actin-binding protein anillin, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Sun, L, Guan, R, Lee, I.-J, Liu, Y, Chen, M, Wang, J, Wu, J, Chen, Z. 登録日 2015-01-16 公開日 2015-07-15 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.092 Å) 主引用文献 Mechanistic insights into the anchorage of the contractile ring by anillin and mid1 Dev.Cell, 33, 2015
3CH5	The crystal structure of the RanGDP-Nup153ZnF2 complex 分子名称: Fragment of Nuclear pore complex protein Nup153, GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Vetter, I.R, Schrader, N. 登録日 2008-03-07 公開日 2008-07-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Crystal Structure of the Ran-Nup153ZnF2 Complex: a General Ran Docking Site at the Nuclear Pore Complex Structure, 16, 2008
3CPH	Crystal structure of Sec4 in complex with Rab-GDI 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rab GDP-dissociation inhibitor, ... 著者 Kravchenko, S, Ignatev, A, Goody, R.S, Rak, A, Pylypenko, O. 登録日 2008-03-31 公開日 2008-05-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A structural model of the GDP dissociation inhibitor rab membrane extraction mechanism. J.Biol.Chem., 283, 2008
4XSH	The complex structure of C3cer exoenzyme and GTP bound RhoA (NADH-bound state) 分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... 著者 Toda, A, Tsurumura, T, Yoshida, T, Tsuge, H. 登録日 2015-01-22 公開日 2015-06-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure. J.Biol.Chem., 290, 2015
3CPJ	Crystal structure of Ypt31 in complex with yeast Rab-GDI 分子名称: CHLORIDE ION, GTP-binding protein YPT31/YPT8, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Kravchenko, S, Ignatev, A, Goody, R.S, Rak, A, Pylypenko, O. 登録日 2008-03-31 公開日 2008-05-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 A structural model of the GDP dissociation inhibitor rab membrane extraction mechanism. J.Biol.Chem., 283, 2008

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