PDB: 47011 件ウェブページステータス検索Chemie searchBIRD

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8AHH	PAC FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery 分子名称: 5-cyano-~{N}-methyl-pyrazolo[1,5-a]pyridine-3-carboxamide, Serine/threonine-protein kinase PAK 4 著者 Baker, L.M, Murray, J.B, Hubbard, R.E. 登録日 2022-07-21 公開日 2022-09-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.037 Å) 主引用文献 PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery. Rsc Med Chem, 13, 2022
8AHG	PAC-FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery 分子名称: Serine/threonine-protein kinase PAK 4, ~{N}-methyl-3-propan-2-yl-1~{H}-pyrazolo[3,4-c]pyridine-4-carboxamide 著者 Baker, L.M, Murray, J.B, Hubbard, R.E. 登録日 2022-07-21 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.885 Å) 主引用文献 PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery. Rsc Med Chem, 13, 2022
8AHE	PAC-FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery 分子名称: SULFATE ION, UDP-N-acetylglucosamine 2-epimerase, ~{N},5-dimethyl-1-phenyl-pyrazole-4-sulfonamide 著者 Baker, L.M, Murray, J.B, Hubbard, R.E. 登録日 2022-07-21 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.108 Å) 主引用文献 PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery. Rsc Med Chem, 13, 2022
8AHF	PAC-FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery 分子名称: (2~{R},4~{S})-4-[bis(fluoranyl)methoxy]-~{N}-methyl-1-(2~{H}-pyrazolo[4,3-b]pyridin-6-ylcarbonyl)pyrrolidine-2-carboxamide, SULFATE ION, UDP-N-acetylglucosamine 2-epimerase 著者 Baker, L.M, Murray, J.B, Hubbard, R.E. 登録日 2022-07-21 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.271 Å) 主引用文献 PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery. Rsc Med Chem, 13, 2022
8AHI	PAC-FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery 分子名称: Serine/threonine-protein kinase PAK 4, ~{N}-methyl-1,3-benzothiazole-6-carboxamide 著者 Baker, L.M, Murray, J.B, Hubbard, R.E. 登録日 2022-07-21 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery. Rsc Med Chem, 13, 2022
6VDK	CryoEM structure of HIV-1 conserved Intasome Core 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Li, M, Chen, X, Craigie, R. 登録日 2019-12-27 公開日 2020-02-05 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies. J.Mol.Biol., 432, 2020
7NBN	Allostery through DNA drives phenotype switching 分子名称: AddAB promoter 著者 Rosenblum, G, Elad, N, Rozenberg, H, Wiggers, F, Jungwirth, J, Hofmann, H. 登録日 2021-01-27 公開日 2021-04-07 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Allostery through DNA drives phenotype switching. Nat Commun, 12, 2021
3HOT	Crystal structure of the Mos1 mariner paired end complex with Mn 分子名称: MANGANESE (II) ION, Mos1 NTS inverted repeat DNA, Mos1 TS inverted repeat DNA, ... 著者 Richardson, J.M, Walkinshaw, M.D. 登録日 2009-06-03 公開日 2009-09-22 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Molecular architecture of the Mos1 paired-end complex: the structural basis of DNA transposition in a eukaryote Cell(Cambridge,Mass.), 138, 2009
2MLK	Three-dimensional structure of the C-terminal DNA-binding domain of RstA protein from Klebsiella pneumoniae 分子名称: RstA 著者 Fang, P, Chen, S, Cheng, Y, Chang, C, Yu, T, Huang, T. 登録日 2014-03-02 公開日 2014-07-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural dynamics of the two-component response regulator RstA in recognition of promoter DNA element. Nucleic Acids Res., 42, 2014
2H9S	Crystal Structure of Homo-DNA and Nature's Choice of Pentose over Hexose in the Genetic System 分子名称: 5'-D(*(XCT)P*(XGU)P*(XAD)P*(XAD)P*(XTH)P*(XTH)P*(XCT)P*(XGU))-3', MAGNESIUM ION 著者 Egli, M, Pallan, P.S. 登録日 2006-06-11 公開日 2006-12-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of homo-DNA and nature's choice of pentose over hexose in the genetic system. J.Am.Chem.Soc., 128, 2006
1NGN	Mismatch repair in methylated DNA. Structure of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4 分子名称: methyl-CpG binding protein MBD4 著者 Wu, P, Qiu, C, Sohail, A, Zhang, X, Bhagwat, A.S, Cheng, X. 登録日 2002-12-17 公開日 2003-03-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4 J.Biol.Chem., 278, 2003
4Z4B	2-Pyridyl Hoechst - a New Generation DNA-Binding Radioprotector 分子名称: 5-(4-methylpiperazin-1-yl)-2'-(pyridin-2-yl)-1H,1'H-2,5'-bibenzimidazole, DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3'), MAGNESIUM ION 著者 Wee, J.-Y, Dobson, R.C.J, White, J.M. 登録日 2015-04-01 公開日 2016-05-04 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9652 Å) 主引用文献 2-Pyridyl Hoechst - a New Generation DNA-Binding Radioprotector To Be Published
1NZB	Crystal structure of wild type Cre recombinase-loxP synapse 分子名称: Cre recombinase, IODIDE ION, MAGNESIUM ION, ... 著者 Ennifar, E, Meyer, J.E.W, Buchholz, F, Stewart, A.F, Suck, D. 登録日 2003-02-17 公開日 2003-09-16 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation Nucleic Acids Res., 31, 2003
3HOS	Crystal structure of the mariner Mos1 paired end complex with Mg 分子名称: MAGNESIUM ION, Mos1 NTS inverted repeat DNA, Mos1 TS inverted repeat DNA, ... 著者 Richardson, J.M, Walkinshaw, M.D. 登録日 2009-06-03 公開日 2009-09-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Molecular architecture of the Mos1 paired-end complex: the structural basis of DNA transposition in a eukaryote Cell(Cambridge,Mass.), 138, 2009
8WOH	human dsDNA sensor CCDC25 complexed with 18bp DNA 分子名称: 18bp DNA, Coiled-coil domain-containing protein 25 著者 Wen, Y, Wu, B.X. 登録日 2023-10-07 公開日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 human dsDNA sensor CCDC25 complexed with 18bp DNA To Be Published
5GN3	Structure of selenomethionine-labelled Uracil DNA glycosylase (BdiUNG) from Bradyrhizobium diazoefficiens 分子名称: Blr0248 protein 著者 Patil, V.V, Chembazhi, U.V, Varshney, U, Woo, E. 登録日 2016-07-19 公開日 2017-05-03 最終更新日 2017-06-14 実験手法 X-RAY DIFFRACTION (2.281 Å) 主引用文献 Uracil DNA glycosylase (UDG) activities in Bradyrhizobium diazoefficiens: characterization of a new class of UDG with broad substrate specificity Nucleic Acids Res., 45, 2017
2QKK	Human RNase H catalytic domain mutant D210N in complex with 14-mer RNA/DNA hybrid 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*G)-3', ... 著者 Nowotny, M, Gaidamakov, S.A, Ghirlando, R, Cerritelli, S.M, Crouch, R.J, Yang, W. 登録日 2007-07-11 公開日 2007-11-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription Mol.Cell, 28, 2007
1CA5	INTERCALATION SITE OF HYPERTHERMOPHILE CHROMOSOMAL PROTEIN SSO7D/SAC7D BOUND TO DNA 分子名称: 5'-D(*GP*TP*GP*AP*TP*CP*AP*C)-3', CHROMOSOMAL PROTEIN SAC7D 著者 Su, S, Gao, Y.-G, Robinson, H, Shriver, J.W, Wang, A.H.-J. 登録日 1999-02-23 公開日 2000-02-23 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of the chromosomal proteins Sso7d/Sac7d bound to DNA containing T-G mismatched base-pairs J.Mol.Biol., 303, 2000
1OUQ	Crystal structure of wild-type Cre recombinase-loxP synapse 分子名称: Cre recombinase, IODIDE ION, MAGNESIUM ION, ... 著者 Ennifar, E, Meyer, J.E.W, Buchholz, F, Stewart, A.F, Suck, D. 登録日 2003-03-25 公開日 2003-09-16 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation Nucleic Acids Res., 31, 2003
1CA6	INTERCALATION SITE OF HYPERTHERMOPHILE CHROMOSOMAL PROTEIN SSO7D/SAC7D BOUND TO DNA 分子名称: 5'-D(*GP*TP*GP*AP*TP*CP*GP*C)-3', CHROMOSOMAL PROTEIN SAC7D 著者 Su, S, Gao, Y.-G, Robinson, H, Shriver, J.W, Wang, A.H.-J. 登録日 1999-02-23 公開日 2000-02-23 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of the chromosomal proteins Sso7d/Sac7d bound to DNA containing T-G mismatched base-pairs J.Mol.Biol., 303, 2000
4LTH	Dehydration/Rehydration of a Nucleic Acid system containing a Polypyridyl Ruthenium Complex at 97% relative humidity (3/7) 分子名称: BARIUM ION, DNA, Ru(tap)2(dppz) complex 著者 Hall, J.P, Sanchez-Weatherby, J, Cardin, C.J. 登録日 2013-07-23 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Controlled Dehydration of a Ruthenium Complex-DNA Crystal Induces Reversible DNA Kinking. J.Am.Chem.Soc., 136, 2014
1R0A	Crystal structure of HIV-1 reverse transcriptase covalently tethered to DNA template-primer solved to 2.8 angstroms 分子名称: 5'-D(*A*TP*GP*CP*AP*TP*CP*GP*GP*CP*GP*CP*TP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*GP*GP*T)-3', 5'-D(*C*CP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*AP*GP*CP*GP*CP*CP*GP*(2DA))-3', GLYCEROL, ... 著者 Tuske, S, Ding, J, Arnold, E. 登録日 2003-09-19 公開日 2004-08-03 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Nonnucleoside inhibitor binding affects the interactions of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase with DNA. J.Virol., 78, 2004
8UJT	Crystal structure of human polymerase eta with incoming dAMPnPP nucleotide opposite urea lesion 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(XB9)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Tomar, R, Egli, M, Stone, M.P. 登録日 2023-10-11 公開日 2024-03-20 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Replication Bypass of the N -(2-Deoxy-d-erythro-pentofuranosyl)-urea DNA Lesion by Human DNA Polymerase eta. Biochemistry, 63, 2024
1QUM	CRYSTAL STRUCTURE OF ESCHERICHIA COLI ENDONUCLEASE IV IN COMPLEX WITH DAMAGED DNA 分子名称: 5'-D(*(3DR)P*CP*GP*AP*CP*GP*A)-3', 5'-D(*CP*GP*TP*CP*C)-3', 5'-D(*TP*CP*GP*TP*CP*GP*GP*GP*GP*AP*CP*G)-3', ... 著者 Hosfield, D.J, Guan, Y, Haas, B.J, Cunningham, R.P, Tainer, J.A. 登録日 1999-07-01 公開日 1999-08-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis. Cell(Cambridge,Mass.), 98, 1999
7YVW	NMR determination of the 2:1 binding motif structure involving cytosine flipping out for the recognition of the CGG/CGG triad DNA 分子名称: 3-[3-[(7-methyl-1,8-naphthyridin-2-yl)carbamoyloxy]propylamino]propyl ~{N}-(7-methyl-1,8-naphthyridin-2-yl)carbamate, DNA (5'-D(*CP*AP*TP*TP*CP*GP*GP*TP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*AP*CP*GP*GP*AP*AP*TP*G)-3') 著者 Furuita, K, Yamada, T, Sakurabayashi, S, Nomura, M, Kojima, C, Nakatani, K. 登録日 2022-08-19 公開日 2023-06-14 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR determination of the 2:1 binding complex of naphthyridine carbamate dimer (NCD) and CGG/CGG triad in double-stranded DNA. Nucleic Acids Res., 50, 2022

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