8AHE
PAC-FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery
Summary for 8AHE
Entry DOI | 10.2210/pdb8ahe/pdb |
Descriptor | UDP-N-acetylglucosamine 2-epimerase, ~{N},5-dimethyl-1-phenyl-pyrazole-4-sulfonamide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | inhibitor, complex, epimerase, technology, isomerase |
Biological source | Bacillus anthracis |
Total number of polymer chains | 2 |
Total formula weight | 85203.14 |
Authors | Baker, L.M.,Murray, J.B.,Hubbard, R.E. (deposition date: 2022-07-21, release date: 2022-09-14, Last modification date: 2024-01-31) |
Primary citation | Ma, H.,Murray, J.B.,Luo, H.,Cheng, X.,Chen, Q.,Song, C.,Duan, C.,Tan, P.,Zhang, L.,Liu, J.,Morgan, B.A.,Li, J.,Wan, J.,Baker, L.M.,Finnie, W.,Guetzoyan, L.,Harris, R.,Hendrickson, N.,Matassova, N.,Simmonite, H.,Smith, J.,Hubbard, R.E.,Liu, G. PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery. Rsc Med Chem, 13:1341-1349, 2022 Cited by PubMed: 36426238DOI: 10.1039/d2md00197g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.108 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)