8AHI

PAC-FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery

Summary for 8AHI

Entry DOI	10.2210/pdb8ahi/pdb
Descriptor	Serine/threonine-protein kinase PAK 4, ~{N}-methyl-1,3-benzothiazole-6-carboxamide (3 entities in total)
Functional Keywords	protein kinase, pak4, atp-binding, transferase, technology
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	33572.98
Authors	Baker, L.M.,Murray, J.B.,Hubbard, R.E. (deposition date: 2022-07-21, release date: 2022-09-14, Last modification date: 2024-01-31)
Primary citation	Ma, H.,Murray, J.B.,Luo, H.,Cheng, X.,Chen, Q.,Song, C.,Duan, C.,Tan, P.,Zhang, L.,Liu, J.,Morgan, B.A.,Li, J.,Wan, J.,Baker, L.M.,Finnie, W.,Guetzoyan, L.,Harris, R.,Hendrickson, N.,Matassova, N.,Simmonite, H.,Smith, J.,Hubbard, R.E.,Liu, G. PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery. Rsc Med Chem, 13:1341-1349, 2022 Cited by PubMed: 36426238 DOI: 10.1039/d2md00197g PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.69 Å)

Structure validation