2CIJ
| membrane-bound glutamate carboxypeptidase II (GCPII) with bound methionine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Barinka, C, Plechanovova, A, Rulisek, L, Mlcochova, P, Majer, P, Slusher, B.S, Hilgenfeld, R, Mesters, J.R, Konvalinka, J. | 登録日 | 2006-03-21 | 公開日 | 2007-03-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Glutamate Carboxypeptidase II Handbook of Metalloproteins, 4, 2011
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2F2L
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2FNJ
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2FSE
| Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen | 分子名称: | Collagen alpha-1(II), H-2 class II histocompatibility antigen, E-K alpha chain, ... | 著者 | Ivey, R.A, Rosloniec, E.F, Whittington, K.B, Kang, A.H, Park, H.W. | 登録日 | 2006-01-22 | 公開日 | 2006-09-19 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystallographic Structure of a Rheumatoid Arthritis MHC Susceptibility Allele, HLA-DR1 (DRB1*0101), Complexed with the Immunodominant Determinant of Human Type II Collagen. J.Immunol., 177, 2006
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2FO4
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3RBU
| N-terminally AviTEV-tagged Human Glutamate Carboxypeptidase II in complex with 2-PMPA | 分子名称: | (2S)-2-(PHOSPHONOMETHYL)PENTANEDIOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Tykvart, J, Sacha, P, Barinka, C, Starkova, J, Knedlik, T, Lubkowski, J, Konvalinka, J. | 登録日 | 2011-03-30 | 公開日 | 2012-01-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Efficient and versatile one-step affinity purification of in vivo biotinylated proteins: Expression, characterization and structure analysis of recombinant human glutamate carboxypeptidase II. Protein Expr.Purif., 82, 2012
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2ZZ8
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3SIQ
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3SIR
| Crystal Structure of drICE | 分子名称: | Caspase | 著者 | Li, X, Wang, J, Shi, Y. | 登録日 | 2011-06-20 | 公開日 | 2011-08-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE. Nat Commun, 2, 2011
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3SJX
| X-ray structure of human glutamate carboxypeptidase II (the E424A inactive mutant) in complex with N-acetyl-aspartyl-methionine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Plechanovova, A, Byun, Y, Alquicer, G, Skultetyova, L, Mlcochova, P, Nemcova, A, Kim, H, Navratil, M, Mease, R, Lubkowski, J, Pomper, M, Konvalinka, J, Rulisek, L, Barinka, C. | 登録日 | 2011-06-22 | 公開日 | 2011-10-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Novel Substrate-Based Inhibitors of Human Glutamate Carboxypeptidase II with Enhanced Lipophilicity. J.Med.Chem., 54, 2011
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3BI0
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3B1C
| Crystal structure of betaC-S lyase from Streptococcus anginosus: Internal aldimine form | 分子名称: | BetaC-S lyase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Kezuka, Y, Yoshida, Y, Nonaka, T. | 登録日 | 2011-06-29 | 公開日 | 2012-06-27 | 最終更新日 | 2014-01-22 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structural insights into catalysis by beta C-S lyase from Streptococcus anginosus Proteins, 80, 2012
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3B7R
| Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040 | 分子名称: | IMIDAZOLE, Leukotriene A-4 hydrolase, N-[3-[(1-AMINOETHYL)(HYDROXY)PHOSPHORYL]-2-(1,1'-BIPHENYL-4-YLMETHYL)PROPANOYL]ALANINE, ... | 著者 | Tholander, F, Haeggstrom, J, Thunnissen, M, Muroya, A, Roques, B.-P, Fournie-Zaluski, M.-C. | 登録日 | 2007-10-31 | 公開日 | 2008-09-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.811 Å) | 主引用文献 | Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15, 2008
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3B1D
| Crystal structure of betaC-S lyase from Streptococcus anginosus in complex with L-serine: External aldimine form | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BetaC-S lyase, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Kezuka, Y, Yoshida, Y, Nonaka, T. | 登録日 | 2011-06-29 | 公開日 | 2012-06-27 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Structural insights into catalysis by beta C-S lyase from Streptococcus anginosus Proteins, 80, 2012
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3SJG
| Human glutamate carboxypeptidase II (E424A inactive mutant ) in complex with N-acetyl-aspartyl-aminooctanoic acid | 分子名称: | (2S)-2-[(N-acetyl-L-alpha-aspartyl)amino]nonanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Plechanovova, A, Byun, Y, Alquicer, G, Skultetyova, L, Mlcochova, P, Nemcova, A, Kim, H, Navratil, M, Mease, R, Lubkowski, J, Pomper, M, Konvalinka, J, Rulisek, L, Barinka, C. | 登録日 | 2011-06-21 | 公開日 | 2011-10-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Novel Substrate-Based Inhibitors of Human Glutamate Carboxypeptidase II with Enhanced Lipophilicity. J.Med.Chem., 54, 2011
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3SJE
| X-ray structure of human glutamate carboxypeptidase II (the E424A inactive mutant) in complex with N-acetyl-aspartyl-aminononanoic acid | 分子名称: | (2S)-2-[(N-acetyl-L-alpha-aspartyl)amino]nonanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Plechanovova, A, Byun, Y, Alquicer, G, Skultetyova, L, Mlcochova, P, Nemcova, A, Kim, H, Navratil, M, Mease, R, Lubkowski, J, Pomper, M, Konvalinka, J, Rulisek, L, Barinka, C. | 登録日 | 2011-06-21 | 公開日 | 2011-10-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Novel Substrate-Based Inhibitors of Human Glutamate Carboxypeptidase II with Enhanced Lipophilicity. J.Med.Chem., 54, 2011
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3BEW
| 10mer Crystal Structure of chicken MHC class I haplotype B21 | 分子名称: | 10-mer from Tubulin beta-6 chain, Beta-2-microglobulin, Major histocompatibility complex class I glycoprotein haplotype B21 | 著者 | Koch, M, Camp, S, Collen, T, Avila, D, Salomonsen, J, Wallny, H.J, van Hateren, A, Hunt, L, Jacob, J.P, Johnston, F, Marston, D.A, Shaw, I, Dunbar, P.R, Cerundolo, V, Jones, E.Y, Kaufman, J. | 登録日 | 2007-11-20 | 公開日 | 2008-01-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structures of an MHC class I molecule from b21 chickens illustrate promiscuous Peptide binding Immunity, 27, 2007
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3B1E
| Crystal structure of betaC-S lyase from Streptococcus anginosus in complex with L-serine: alpha-Aminoacrylate form | 分子名称: | 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ... | 著者 | Kezuka, Y, Yoshida, Y, Nonaka, T. | 登録日 | 2011-06-29 | 公開日 | 2012-06-27 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structural insights into catalysis by beta C-S lyase from Streptococcus anginosus Proteins, 80, 2012
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3B7S
| [E296Q]LTA4H in complex with RSR substrate | 分子名称: | ACETIC ACID, GLYCEROL, Leukotriene A-4 hydrolase, ... | 著者 | Tholander, F, Haeggstrom, J, Thunnissen, M, Muroya, A, Roques, B.-P, Fournie-Zaluski, M.-C. | 登録日 | 2007-10-31 | 公開日 | 2008-09-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.465 Å) | 主引用文献 | Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15, 2008
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3B7U
| Leukotriene A4 Hydrolase Complexed with KELatorphan | 分子名称: | ACETIC ACID, IMIDAZOLE, Leukotriene A-4 hydrolase, ... | 著者 | Tholander, F, Haeggstrom, J, Thunnissen, M, Muroya, A, Roques, B.-P, Fournie-Zaluski, M.-C. | 登録日 | 2007-10-31 | 公開日 | 2008-09-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15, 2008
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2ZE9
| Crystal structure of H168A mutant of phospholipase D from Streptomyces antibioticus, as a complex with phosphatidylcholine | 分子名称: | (2R)-3-(phosphonooxy)propane-1,2-diyl diheptanoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Phospholipase D | 著者 | Suzuki, A, Toda, H, Iwasaki, Y, Yamane, T, Yamane, T. | 登録日 | 2007-12-06 | 公開日 | 2007-12-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of phospholipase D from streptomyces antibioticus To be Published
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3B7T
| [E296Q]LTA4H in complex with Arg-Ala-Arg substrate | 分子名称: | IMIDAZOLE, Leukotriene A-4 hydrolase, RAR peptide, ... | 著者 | Tholander, F, Haeggstrom, J, Thunnissen, M, Muroya, A, Roques, B.-P, Fournie-Zaluski, M.-C. | 登録日 | 2007-10-31 | 公開日 | 2008-09-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15, 2008
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3BEV
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3BI1
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3B9P
| Spastin | 分子名称: | CG5977-PA, isoform A, CHLORIDE ION | 著者 | Roll-Mecak, A, Vale, R.D. | 登録日 | 2007-11-06 | 公開日 | 2008-01-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin. Nature, 451, 2008
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