2FO4

Enhanced MHC class I binding and immune responses through anchor modification of the non-canonical tumor associated MUC1-8 peptide

Summary for 2FO4

• Entry DOI: 10.2210/pdb2fo4/pdb
• Related: 1G7Q
• Descriptor: H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, 8-mer from Mucin-1, ... (8 entities in total)
• Functional Keywords: anchor modifications, h-2kb, muc1, non-canonical peptide, muc1-8, vaccine design, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 3
• Total formula weight: 45506.89

Authors

Lazoura, E.,Ramsland, P.A. (deposition date: 2006-01-12, release date: 2006-11-14, Last modification date: 2023-10-25)

• Primary citation: Lazoura, E.,Lodding, J.,Farrugia, W.,Ramsland, P.A.,Stevens, J.,Wilson, I.A.,Pietersz, G.A.,Apostolopoulos, V.; Enhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide; Immunology, 119:306-316, 2006; PubMed: 17067310; DOI: 10.1111/j.1365-2567.2006.02434.x

Experimental method

X-RAY DIFFRACTION (2.7 Å)