PDB: 84 件ウェブページステータス検索Chemie searchBIRD

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5K1B	Crystal structure of the UAF1/USP12 complex in F222 space group 分子名称: Ubiquitin carboxyl-terminal hydrolase 12, WD repeat-containing protein 48, ZINC ION 著者 Li, H, D'Andrea, A.D, Zheng, N. 登録日 2016-05-18 公開日 2016-07-20 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20. Mol.Cell, 63, 2016
6GH9	USP15 catalytic domain in complex with small molecule 分子名称: 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, DIMETHYL SULFOXIDE, Ubiquitin carboxyl-terminal hydrolase 15, ... 著者 Ward, S.J, Gratton, H.E, Caulton, S.G, Emsley, J, Dreveny, I. 登録日 2018-05-06 公開日 2018-09-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel. J. Biol. Chem., 293, 2018
6IIK	USP14 catalytic domain with IU1 分子名称: 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(pyrrolidin-1-yl)ethan-1-one, Ubiquitin carboxyl-terminal hydrolase 14 著者 Mei, Z.Q, Wang, Y.W, He, W, Wang, F. 登録日 2018-10-06 公開日 2018-12-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade. Cell Res., 28, 2018
6IIL	USP14 catalytic domain bind to IU1-47 分子名称: 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(piperidin-1-yl)ethan-1-one, Ubiquitin carboxyl-terminal hydrolase 14 著者 Mei, Z.Q, Wang, Y.W, Wang, F, Wang, J.W, He, W, Ding, S, Li, J.W. 登録日 2018-10-07 公開日 2018-12-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade. Cell Res., 28, 2018
6GHA	USP15 catalytic domain structure 分子名称: Ubiquitin carboxyl-terminal hydrolase 15,Ubiquitin carboxyl-terminal hydrolase 15, ZINC ION 著者 Ward, S.J, Gratton, H.E, Caulton, S.G, Emsley, J, Dreveny, I. 登録日 2018-05-06 公開日 2018-09-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel. J. Biol. Chem., 293, 2018
6IIM	USP14 catalytic domain with IU1-206 分子名称: 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(4-hydroxypiperidin-1-yl)ethan-1-one, Ubiquitin carboxyl-terminal hydrolase 14 著者 Mei, Z.Q, Wang, J.W, Wang, F, Wang, Y.W. 登録日 2018-10-07 公開日 2018-12-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade. Cell Res., 28, 2018
6IIN	USP14 catalytic domain with IU1-248 分子名称: 4-{3-[(4-hydroxypiperidin-1-yl)acetyl]-2,5-dimethyl-1H-pyrrol-1-yl}benzonitrile, Ubiquitin carboxyl-terminal hydrolase 14 著者 Mei, Z.Q, Wang, J.W, Wang, F, Wang, Y.W. 登録日 2018-10-07 公開日 2018-12-19 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade. Cell Res., 28, 2018
1WGG	Solution Structure of the N-terminal Ubiquitin-like Domain of Mouse Ubiquitin Specific Protease 14 (USP14) 分子名称: Ubiquitin carboxyl-terminal hydrolase 14 著者 Zhao, C, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-28 公開日 2004-11-28 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the N-terminal Ubiquitin-like Domain of Mouse Ubiquitin Specific Protease 14 (USP14) To be Published
1WH0	Solution structure of the CS domain of human USP19 分子名称: Ubiquitin carboxyl-terminal hydrolase 19 著者 Nakanishi, T, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-28 公開日 2004-11-28 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the CS domain of human USP19 To be Published
7W3C	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED0_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3H	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W39	Structure of USP14-bound human 26S proteasome in state EA2.1_UBL 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3J	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SC_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3B	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED5_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3A	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED4_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3G	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.0_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W37	Structure of USP14-bound human 26S proteasome in state EA1_UBL 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3K	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD4_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3F	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED1_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W38	Structure of USP14-bound human 26S proteasome in state EA2.0_UBL 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-04 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3I	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SB_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-18 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3M	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD5_USP14 分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... 著者 Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. 登録日 2021-11-25 公開日 2022-05-18 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
6RRV	Crystal structure of the Sir4 H-BRCT domain 分子名称: BROMIDE ION, CHLORIDE ION, Regulatory protein SIR4 著者 Deshpande, I, Keusch, J.J, Challa, K, Iesmantavicius, V, Gasser, S.M, Gut, H. 登録日 2019-05-20 公開日 2019-09-18 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin. Embo J., 38, 2019
6G2G	Fe-S assembly Cfd1 分子名称: Cytosolic Fe-S cluster assembly factor CFD1, IRON/SULFUR CLUSTER, SULFATE ION 著者 Jeoung, J.H, Dobbek, H. 登録日 2018-03-23 公開日 2019-01-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Function and crystal structure of the dimeric P-loop ATPase CFD1 coordinating an exposed [4Fe-4S] cluster for transfer to apoproteins. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6QTM	Crystal structure of the Sir4 H-BRCT domain in complex with Ty5 pS1095 peptide 分子名称: Regulatory protein SIR4, Ribonuclease H, SULFATE ION 著者 Gut, H, Deshpande, I, Keusch, J.J, Challa, K, Iesmantavicius, V, Gasser, S.M. 登録日 2019-02-25 公開日 2019-09-18 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin. Embo J., 38, 2019

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