6QTM

Crystal structure of the Sir4 H-BRCT domain in complex with Ty5 pS1095 peptide

Summary for 6QTM

• Entry DOI: 10.2210/pdb6qtm/pdb
• Related: 6QSZ
• Descriptor: Regulatory protein SIR4, Ribonuclease H, SULFATE ION, ... (4 entities in total)
• Functional Keywords: heterochromatin, nuclear protein
• Biological source: Saccharomyces cerevisiae S288C; More
• Total number of polymer chains: 6
• Total formula weight: 51235.14

Authors

Gut, H.,Deshpande, I.,Keusch, J.J.,Challa, K.,Iesmantavicius, V.,Gasser, S.M. (deposition date: 2019-02-25, release date: 2019-09-18, Last modification date: 2021-08-11)

• Primary citation: Deshpande, I.,Keusch, J.J.,Challa, K.,Iesmantavicius, V.,Gasser, S.M.,Gut, H.; The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin.; Embo J., 38:e101744-e101744, 2019; PubMed: 31515872; DOI: 10.15252/embj.2019101744

Experimental method

X-RAY DIFFRACTION (3 Å)