6SHS
 
 | | Abeta fibril (Morphology I) | | 分子名称: | Amyloid-beta precursor protein | | 著者 | Kollmer, M, Fandrich, M. | | 登録日 | 2019-08-08 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM structure and polymorphism of A beta amyloid fibrils purified from Alzheimer's brain tissue.
Nat Commun, 10, 2019
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6SZF
 | | Solution structure of the amyloid beta-peptide (1-42) | | 分子名称: | Amyloid-beta precursor protein | | 著者 | Grimaldi, M, Santoro, A, Stillitano, I, Buonocore, M, D'Ursi, A.M. | | 登録日 | 2019-10-02 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Exploring the Early Stages of the Amyloid A beta (1-42) Peptide Aggregation Process: An NMR Study.
Pharmaceuticals, 14, 2021
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6TI7
 | | Mixing Abeta(1-40) and Abeta(1-42) peptides generates unique amyloid fibrils | | 分子名称: | Amyloid-beta precursor protein | | 著者 | Cerofolini, L, Ravera, E, Bologna, S, Wiglenda, T, Boddrich, A, Purfurst, B, Benilova, A, Korsak, M, Gallo, G, Rizzo, D, Gonnelli, L, Fragai, M, De Strooper, B, Wanker, E.E, Luchinat, C. | | 登録日 | 2019-11-21 | | 公開日 | 2020-07-22 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Mixing A beta (1-40) and A beta (1-42) peptides generates unique amyloid fibrils.
Chem.Commun.(Camb.), 56, 2020
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6TI5
 | | A New Structural Model of Abeta(1-40) Fibrils | | 分子名称: | Amyloid-beta precursor protein | | 著者 | Bertini, I, Gonnelli, L, Luchinat, C, Mao, J, Nesi, A. | | 登録日 | 2019-11-21 | | 公開日 | 2020-07-22 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Mixing A beta (1-40) and A beta (1-42) peptides generates unique amyloid fibrils.
Chem.Commun.(Camb.), 56, 2020
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6TI6
 | | Mixing Abeta(1-40) and Abeta(1-42) peptides generates unique amyloid fibrils | | 分子名称: | Amyloid-beta precursor protein | | 著者 | Cerofolini, L, Ravera, E, Bologna, S, Wiglenda, T, Boddrich, A, Purfurst, B, Benilova, A, Korsak, M, Gallo, G, Rizzo, D, Gonnelli, L, Fragai, M, De Strooper, B, Wanker, E.E, Luchinat, C. | | 登録日 | 2019-11-21 | | 公開日 | 2020-07-22 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Mixing A beta (1-40) and A beta (1-42) peptides generates unique amyloid fibrils.
Chem.Commun.(Camb.), 56, 2020
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1AMB
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1AMC
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1AML
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1BJC
 | | SOLUTION NMR STRUCTURE OF AMYLOID BETA[F16], RESIDUES 1-28, 15 STRUCTURES | | 分子名称: | AMYLOID BETA-PEPTIDE | | 著者 | Poulsen, S.-A, Watson, A.A, Craik, D.J. | | 登録日 | 1998-06-23 | | 公開日 | 1998-11-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F)
J.Struct.Biol., 130, 2000
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1BA4
 | | THE SOLUTION STRUCTURE OF AMYLOID BETA-PEPTIDE (1-40) IN A WATER-MICELLE ENVIRONMENT. IS THE MEMBRANE-SPANNING DOMAIN WHERE WE THINK IT IS? NMR, 10 STRUCTURES | | 分子名称: | AMYLOID BETA-PEPTIDE | | 著者 | Coles, M, Bicknell, W, Watson, A.A, Fairlie, D.P, Craik, D.J. | | 登録日 | 1998-04-07 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?
Biochemistry, 37, 1998
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1BA6
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1BJB
 | | SOLUTION NMR STRUCTURE OF AMYLOID BETA[E16], RESIDUES 1-28, 14 STRUCTURES | | 分子名称: | AMYLOID BETA-PEPTIDE | | 著者 | Poulsen, S.-A, Watson, A.A, Craik, D.J. | | 登録日 | 1998-06-23 | | 公開日 | 1998-11-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F)
J.Struct.Biol., 130, 2000
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8AZT
 | | Type II amyloid-beta 42 filaments from high-spin supernatants of aqueous extracts from Alzheimer's disease brains | ABeta42 | | 分子名称: | Amyloid-beta precursor protein | | 著者 | Yang, Y, Stern, M.A, Meunier, L.A, Liu, W, Cai, Y.Q, Ericsson, M, Liu, L, Selkoe, J.D, Goedert, M, Scheres, H.W.S. | | 登録日 | 2022-09-06 | | 公開日 | 2022-11-02 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Abundant A beta fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains.
Neuron, 111, 2023
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8AZS
 | | Type I amyloid-beta 42 filaments from high-spin supernatants of aqueous extracts from Alzheimer's disease brains | ABeta42 | | 分子名称: | Amyloid-beta precursor protein | | 著者 | Yang, Y, Stern, M.A, Meunier, L.A, Liu, W, Cai, Y.Q, Ericsson, M, Liu, L, Selkoe, J.D, Goedert, M, Scheres, H.W.S. | | 登録日 | 2022-09-06 | | 公開日 | 2022-11-02 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Abundant A beta fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains.
Neuron, 111, 2023
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8BG0
 | | Amyloid-beta tetrameric filaments with the Arctic mutation (E22G) from Alzheimer's disease brains | ABeta40 | | 分子名称: | Amyloid-beta precursor protein | | 著者 | Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordber, A, Goedert, M, Scheres, S.H.W. | | 登録日 | 2022-10-27 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (1.9 Å) | | 主引用文献 | Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
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8B9R
 | | Molecular structure of Cu(II)-bound amyloid-beta monomer implicated in inhibition of peptide self-assembly in Alzheimer's disease | | 分子名称: | Amyloid-beta A4 protein, COPPER (II) ION | | 著者 | Abelein, A, Ciofi-Baffoni, S, Morman, C, Kumar, R, Giachetti, A, Piccioli, M, Biverstal, H. | | 登録日 | 2022-10-06 | | 公開日 | 2023-02-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular Structure of Cu(II)-Bound Amyloid-beta Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer's Disease.
Jacs Au, 2, 2022
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8BFZ
 | | Amyloid-beta 42 filaments extracted from the human brain with Arctic mutation (E22G) of Alzheimer's disease | ABeta42 | | 分子名称: | Amyloid-beta precursor protein | | 著者 | Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordberg, A, Goedert, M, Scheres, S.H.W. | | 登録日 | 2022-10-27 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
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8BFA
 | | Sarkosyl-extracted AppNL-G-F Abeta42 fibril structure | | 分子名称: | Amyloid-beta precursor protein | | 著者 | Wilkinson, M, Leistner, C, Burgess, A, Goodfellow, S, Deuchars, S, Ranson, N.A, Radford, S.E, Frank, R.A.W. | | 登録日 | 2022-10-24 | | 公開日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | The in-tissue molecular architecture of beta-amyloid pathology in the mammalian brain.
Nat Commun, 14, 2023
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8BFB
 | | Sarkosyl-extracted AppNL-G-F Abeta42 fibril structure (Methoxy-X04-labelled mice) | | 分子名称: | Amyloid-beta precursor protein | | 著者 | Wilkinson, M, Leistner, C, Burgess, A, Goodfellow, S, Deuchars, S, Ranson, N.A, Radford, S.E, Frank, R.A.W. | | 登録日 | 2022-10-24 | | 公開日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The in-tissue molecular architecture of beta-amyloid pathology in the mammalian brain.
Nat Commun, 14, 2023
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8BG9
 | | Murine amyloid-beta filaments with the Arctic mutation (E22G) from APP(NL-G-F) mouse brains | ABeta | | 分子名称: | Amyloid-beta protein 40 | | 著者 | Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordber, A, Goedert, M, Scheres, S.H.W. | | 登録日 | 2022-10-27 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Acta Neuropathol, 145, 2023
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2LMN
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2LNQ
 | | 40-residue D23N beta amyloid fibril | | 分子名称: | P3(40) | | 著者 | Qiang, W, Yau, W, Luo, Y, Mattson, M.P, Tycko, R. | | 登録日 | 2012-01-03 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Antiparallel beta-sheet architecture in Iowa-mutant beta-amyloid fibrils.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2LOH
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2LMO
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2LFM
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