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6TI5

A New Structural Model of Abeta(1-40) Fibrils

Summary for 6TI5
Entry DOI10.2210/pdb6ti5/pdb
NMR InformationBMRB: 34454
DescriptorAmyloid-beta precursor protein (1 entity in total)
Functional Keywordsamyloid beta peptides, alzheimer's disease, supramolecular assembly, protein fibril
Biological sourceHomo sapiens (Human)
Total number of polymer chains16
Total formula weight69373.63
Authors
Bertini, I.,Gonnelli, L.,Luchinat, C.,Mao, J.,Nesi, A. (deposition date: 2019-11-21, release date: 2020-07-22, Last modification date: 2024-06-19)
Primary citationCerofolini, L.,Ravera, E.,Bologna, S.,Wiglenda, T.,Boddrich, A.,Purfurst, B.,Benilova, I.,Korsak, M.,Gallo, G.,Rizzo, D.,Gonnelli, L.,Fragai, M.,De Strooper, B.,Wanker, E.E.,Luchinat, C.
Mixing A beta (1-40) and A beta (1-42) peptides generates unique amyloid fibrils.
Chem.Commun.(Camb.), 56:8830-8833, 2020
Cited by
PubMed: 32749391
DOI: 10.1039/d0cc02463e
PDB entries with the same primary citation
Experimental method
SOLID-STATE NMR
Structure validation

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