6TI5
A New Structural Model of Abeta(1-40) Fibrils
Summary for 6TI5
Entry DOI | 10.2210/pdb6ti5/pdb |
NMR Information | BMRB: 34454 |
Descriptor | Amyloid-beta precursor protein (1 entity in total) |
Functional Keywords | amyloid beta peptides, alzheimer's disease, supramolecular assembly, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 16 |
Total formula weight | 69373.63 |
Authors | Bertini, I.,Gonnelli, L.,Luchinat, C.,Mao, J.,Nesi, A. (deposition date: 2019-11-21, release date: 2020-07-22, Last modification date: 2024-06-19) |
Primary citation | Cerofolini, L.,Ravera, E.,Bologna, S.,Wiglenda, T.,Boddrich, A.,Purfurst, B.,Benilova, I.,Korsak, M.,Gallo, G.,Rizzo, D.,Gonnelli, L.,Fragai, M.,De Strooper, B.,Wanker, E.E.,Luchinat, C. Mixing A beta (1-40) and A beta (1-42) peptides generates unique amyloid fibrils. Chem.Commun.(Camb.), 56:8830-8833, 2020 Cited by PubMed: 32749391DOI: 10.1039/d0cc02463e PDB entries with the same primary citation |
Experimental method | SOLID-STATE NMR |
Structure validation
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