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8AZS

Type I amyloid-beta 42 filaments from high-spin supernatants of aqueous extracts from Alzheimer's disease brains | ABeta42

Summary for 8AZS
Entry DOI10.2210/pdb8azs/pdb
EMDB information15770
DescriptorAmyloid-beta precursor protein (1 entity in total)
Functional Keywordsamyloid, filaments, abeta42, amyloid-beta, cryo-em, protein fibril
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight4520.09
Authors
Yang, Y.,Stern, M.A.,Meunier, L.A.,Liu, W.,Cai, Y.Q.,Ericsson, M.,Liu, L.,Selkoe, J.D.,Goedert, M.,Scheres, H.W.S. (deposition date: 2022-09-06, release date: 2022-11-02, Last modification date: 2024-07-24)
Primary citationStern, A.M.,Yang, Y.,Jin, S.,Yamashita, K.,Meunier, A.L.,Liu, W.,Cai, Y.,Ericsson, M.,Liu, L.,Goedert, M.,Scheres, S.H.W.,Selkoe, D.J.
Abundant A beta fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains.
Neuron, 111:2012-, 2023
Cited by
PubMed: 37167969
DOI: 10.1016/j.neuron.2023.04.007
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.9 Å)
Structure validation

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