PDB: 79 件ウェブページステータス検索Chemie searchBIRD

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4ZGA	Structural basis for inhibition of human autotaxin by four novel compounds 分子名称: (11aS)-6-(4-fluorobenzyl)-5,6,11,11a-tetrahydro-1H-imidazo[1',5':1,6]pyrido[3,4-b]indole-1,3(2H)-dione, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Stein, A.J, Bain, G, Hutchinson, J.H, Evans, J.F. 登録日 2015-04-22 公開日 2015-10-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding. Mol.Pharmacol., 88, 2015
4ZG7	Structural basis for inhibition of human autotaxin by four novel compounds 分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-({6-chloro-7-fluoro-2-methyl-1-[2-oxo-2-(spiro[cyclopropane-1,3'-indol]-1'(2'H)-yl)ethyl]-1H-indol-3-yl}sulfanyl)-2-fluorobenzoic acid, ... 著者 Stein, A.J, Bain, G, Hutchinson, J.H, Evans, J.F. 登録日 2015-04-22 公開日 2015-10-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding. Mol.Pharmacol., 88, 2015
4ZG6	Structural basis for inhibition of human autotaxin by four novel compounds 分子名称: 4-{(Z)-2-[6-chloro-1-(4-fluorobenzyl)-1H-indol-3-yl]-1-cyanoethenyl}benzoic acid, CALCIUM ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, ... 著者 Stein, A.J, Bain, G, Hutchinson, J.H, Evans, J.F. 登録日 2015-04-22 公開日 2015-10-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding. Mol.Pharmacol., 88, 2015
4ZG9	Structural basis for inhibition of human autotaxin by four novel compounds 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(11aS)-6-(4-fluorobenzyl)-1,3-dioxo-5,6,11,11a-tetrahydro-1H-imidazo[1',5':1,6]pyrido[3,4-b]indol-2(3H)-yl]propanoic acid, ... 著者 Stein, A.J, Bain, G, Hutchinson, J.H, Evans, J.F. 登録日 2015-04-22 公開日 2015-10-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding. Mol.Pharmacol., 88, 2015
3WAY	Crystal Structure of Autotaxin in Complex with 4BoA 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2013-05-09 公開日 2013-07-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.746 Å) 主引用文献 Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
3WAX	Crystal Structure of Autotaxin in Complex with 3BoA 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2013-05-09 公開日 2013-07-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.899 Å) 主引用文献 Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
3WAV	Crystal Structure of Autotaxin in Complex with Compound 10 分子名称: (5Z)-5-(3,4-dichlorobenzylidene)-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4(5H)-one, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2013-05-09 公開日 2013-07-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.797 Å) 主引用文献 Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
3WAW	Crystal Structure of Autotaxin in Complex with 2BoA 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2013-05-09 公開日 2013-07-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.954 Å) 主引用文献 Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
4K24	Structure of anti-uPAR Fab ATN-658 in complex with uPAR 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, ... 著者 Huang, M.D, Xu, X, Yuan, C. 登録日 2013-04-08 公開日 2014-02-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b ( alpha M) Plos One, 9, 2014
4GTW	Crystal structure of mouse Enpp1 in complex with AMP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ... 著者 Kato, K, Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2012-08-29 公開日 2012-11-07 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling. Proc.Natl.Acad.Sci.USA, 109, 2012
4GTZ	Crystal structure of mouse Enpp1 in complex with CMP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Kato, K, Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2012-08-29 公開日 2012-11-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.191 Å) 主引用文献 Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling. Proc.Natl.Acad.Sci.USA, 109, 2012
4GTY	Crystal structure of mouse Enpp1 in complex with GMP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Kato, K, Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2012-08-29 公開日 2012-11-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling. Proc.Natl.Acad.Sci.USA, 109, 2012
4GTX	Crystal structure of mouse Enpp1 in complex with TMP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Kato, K, Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2012-08-29 公開日 2012-11-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.201 Å) 主引用文献 Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling. Proc.Natl.Acad.Sci.USA, 109, 2012
4B56	Structure of ectonucleotide pyrophosphatase-phosphodiesterase-1 (NPP1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Jansen, S, Perrakis, A, Ulens, C, Winkler, C, Andries, M, Joosten, R.P, Van Acker, M, Luyten, F.P, Moolenaar, W.H, Bollen, M. 登録日 2012-08-02 公開日 2012-09-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of Npp1, an Ectonucleotide Pyrophosphatase/Phosphodiesterase Involved in Tissue Calcification. Structure, 20, 2012
2XRG	Crystal structure of Autotaxin (ENPP2) in complex with the HA155 boronic acid inhibitor 分子名称: CALCIUM ION, ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 2, IODIDE ION, ... 著者 Hausmann, J, Albers, H.M.H.G, Perrakis, A. 登録日 2010-09-14 公開日 2011-01-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Basis of Substrate Discrimination and Integrin Binding by Autotaxin. Nat.Struct.Mol.Biol., 18, 2011
2XR9	Crystal structure of Autotaxin (ENPP2) 分子名称: CALCIUM ION, ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 2, IODIDE ION, ... 著者 Kamtekar, S, Hausmann, J, Day, J.E, Christodoulou, E, Perrakis, A. 登録日 2010-09-13 公開日 2011-01-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis of substrate discrimination and integrin binding by autotaxin. Nat. Struct. Mol. Biol., 18, 2011
3NKP	Crystal structure of mouse autotaxin in complex with 18:1-LPA 分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O. 登録日 2010-06-20 公開日 2011-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Crystal structure of autotaxin and insight into GPCR activation by lipid mediators Nat.Struct.Mol.Biol., 18, 2011
3NKR	Crystal structure of mouse autotaxin in complex with 22:6-LPA 分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl (4Z,7E,10E,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O. 登録日 2010-06-20 公開日 2011-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.704 Å) 主引用文献 Crystal structure of autotaxin and insight into GPCR activation by lipid mediators Nat.Struct.Mol.Biol., 18, 2011
3NKN	Crystal structure of mouse autotaxin in complex with 14:0-LPA 分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O. 登録日 2010-06-20 公開日 2011-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of autotaxin and insight into GPCR activation by lipid mediators Nat.Struct.Mol.Biol., 18, 2011
3NKO	Crystal structure of mouse autotaxin in complex with 16:0-LPA 分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O. 登録日 2010-06-20 公開日 2011-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of autotaxin and insight into GPCR activation by lipid mediators Nat.Struct.Mol.Biol., 18, 2011
3NKM	Crystal structure of mouse autotaxin 分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O. 登録日 2010-06-20 公開日 2011-01-19 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 Crystal structure of autotaxin and insight into GPCR activation by lipid mediators Nat.Struct.Mol.Biol., 18, 2011
3NKQ	Crystal structure of mouse autotaxin in complex with 18:3-LPA 分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E,12Z,15Z)-octadeca-9,12,15-trienoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nishimasu, H, Ishitani, R, Mihara, E, Takagi, J, Aoki, J, Nureki, O. 登録日 2010-06-20 公開日 2011-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of autotaxin and insight into GPCR activation by lipid mediators Nat.Struct.Mol.Biol., 18, 2011
3BT2	Structure of urokinase receptor, urokinase and vitronectin complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, ... 著者 Huang, M. 登録日 2007-12-27 公開日 2008-03-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes Nat.Struct.Mol.Biol., 15, 2008
3BT1	Structure of urokinase receptor, urokinase and vitronectin complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator, ... 著者 Huang, M. 登録日 2007-12-27 公開日 2008-03-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes Nat.Struct.Mol.Biol., 15, 2008
2JQ8	Solution structure of the Somatomedin B domain from vitronectin produced in Pichia pastoris 分子名称: Vitronectin 著者 Gaardsvoll, H, Hirschberg, D, Nielbo, S, Mayasundari, A, Peterson, C.B, Jansson, A, Jorgensen, T.J.D, Poulsen, F.M. 登録日 2007-05-30 公開日 2007-09-11 最終更新日 2023-12-20 実験手法 SOLUTION NMR 主引用文献 Solution structure of recombinant somatomedin B domain from vitronectin produced in Pichia pastoris Protein Sci., 16, 2007

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