2HP6
 
 | | Crystal structure of the OXA-10 W154A mutant at pH 7.5 | | 分子名称: | Beta-lactamase PSE-2, SULFATE ION | | 著者 | Kerff, F, Falzone, C, Herman, R, Sauvage, E, Charlier, P. | | 登録日 | 2006-07-17 | | 公開日 | 2007-07-03 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases.
Biochemistry, 48, 2009
|
|
2HP9
 | | Crystal Structure of the OXA-10 W154A mutant at pH 6.0 | | 分子名称: | Beta-lactamase PSE-2, SULFATE ION | | 著者 | Kerff, F, Falzone, C, Herman, R, Sauvage, E, Charlier, P. | | 登録日 | 2006-07-17 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases.
Biochemistry, 48, 2009
|
|
2HPB
 | | Crystal structure of the OXA-10 W154A mutant at pH 9.0 | | 分子名称: | Beta-lactamase PSE-2, SULFATE ION | | 著者 | Kerff, F, Falzone, C, Herman, R, Sauvage, E, Charlier, P. | | 登録日 | 2006-07-17 | | 公開日 | 2007-07-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases.
Biochemistry, 48, 2009
|
|
2JE5
 | | STRUCTURAL AND MECHANISTIC BASIS OF PENICILLIN BINDING PROTEIN INHIBITION BY LACTIVICINS | | 分子名称: | (2E)-2-{[(2S)-2-(ACETYLAMINO)-2-CARBOXYETHOXY]IMINO}PENTANEDIOIC ACID, CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, ... | | 著者 | Macheboeuf, P, Fisher, D.S, Brown, T.J, Zervosen, A, Luxen, A, Joris, B, Dessen, A, Schofield, C.J. | | 登録日 | 2007-01-15 | | 公開日 | 2007-08-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and Mechanistic Basis of Penicillin-Binding Protein Inhibition by Lactivicins
Nat.Chem.Biol., 3, 2007
|
|
2JCH
 | | Structural and mechanistic basis of penicillin binding protein inhibition by lactivicins | | 分子名称: | (2E)-2-({(2S)-2-CARBOXY-2-[(PHENOXYACETYL)AMINO]ETHOXY}IMINO)PENTANEDIOIC ACID, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Macheboeuf, P, Fisher, D.S, Brown, T.J, Zervosen, A, Luxen, A, Joris, B, Dessen, A, Schofield, C.J. | | 登録日 | 2006-12-23 | | 公開日 | 2007-08-14 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and Mechanistic Basis of Penicillin-Binding Protein Inhibition by Lactivicins
Nat.Chem.Biol., 3, 2007
|
|
2Z2M
 | | Cefditoren-Acylated Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae | | 分子名称: | (2R)-2-[(1R)-1-{[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-(METHOXYIMINO)ACETYL]AMINO}-2-OXOETHYL]-5-[(Z)-2-(4-METHYL-1,3-THIAZOL-5-YL)VINYL]-3,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC ACID, Penicillin-binding protein 2X, SULFATE ION | | 著者 | Yamada, M, Watanabe, T, Takeuchi, Y. | | 登録日 | 2007-05-23 | | 公開日 | 2007-09-04 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for its High Antimicrobial Activity
Antimicrob.Agents Chemother., 51, 2007
|
|
2Z2L
 | |
3BFC
 | |
3BFF
 | | class A beta-lactamase SED-G238C complexed with faropenem | | 分子名称: | (2R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-5-[(2R)-oxolan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylic acid, (5R,6S)-6-(1-hydroxyethyl)-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, Class A beta-lactamase Sed1, ... | | 著者 | Pernot, L, Petrella, S, Sougakoff, W. | | 登録日 | 2007-11-21 | | 公開日 | 2007-12-18 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | acyl-intermediate structures of the class A beta-lactamase SED-G238C
To be Published
|
|
3BFG
 | | class A beta-lactamase SED-G238C complexed with meropenem | | 分子名称: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, Class A beta-lactamase Sed1 | | 著者 | Pernot, L, Petrella, S, Sougakoff, W. | | 登録日 | 2007-11-21 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | acyl-intermediate structures of the class A beta-lactamase SED-G238C
To be Published
|
|
3BFE
 | |
3BFD
 | |
2V2F
 | | Crystal structure of PBP1a from drug-resistant strain 5204 from Streptococcus pneumoniae | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BARIUM ION, PENICILLIN BINDING PROTEIN 1A | | 著者 | Job, V, Carapito, R, Vernet, T, Dideberg, O, Dessen, A, Zapun, A. | | 登録日 | 2007-06-05 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Common Alterations in Pbp1A from Resistant Streptococcus Pneumoniae Decrease its Reactivity Toward {Beta}-Lactams: Structural Insights.
J.Biol.Chem., 283, 2008
|
|
2ZC4
 | | Penicillin-binding protein 2X (PBP 2X) acyl-enzyme complex (tebipenem) from Streptococcus pneumoniae | | 分子名称: | (4R,5S)-3-(1-(4,5-dihydrothiazol-2-yl)azetidin-3-ylthio)-5-((2S,3R)-3-hydroxy-1-oxobutan-2-yl)-4-methyl-4,5- dihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein 2X, SULFATE ION | | 著者 | Yamada, M, Watanabe, T, Takeuchi, Y. | | 登録日 | 2007-11-02 | | 公開日 | 2008-04-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae
Antimicrob.Agents Chemother., 52, 2008
|
|
2ZC6
 | | Penicillin-binding protein 1A (PBP 1A) acyl-enzyme complex (tebipenem) from Streptococcus pneumoniae | | 分子名称: | (4R,5S)-3-(1-(4,5-dihydrothiazol-2-yl)azetidin-3-ylthio)-5-((2S,3R)-3-hydroxy-1-oxobutan-2-yl)-4-methyl-4,5- dihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein 1A, ZINC ION | | 著者 | Yamada, M, Watanabe, T, Takeuchi, Y. | | 登録日 | 2007-11-02 | | 公開日 | 2008-04-08 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae
Antimicrob.Agents Chemother., 52, 2008
|
|
2ZC5
 | | Penicillin-binding protein 1A (PBP 1A) acyl-enzyme complex (biapenem) from Streptococcus pneumoniae | | 分子名称: | (4R,5S)-3-(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-ylsulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-meth yl-4,5-dihydro-1H-pyrrole-2-carboxylate, Penicillin-binding protein 1A, ZINC ION | | 著者 | Yamada, M, Watanabe, T, Takeuchi, Y. | | 登録日 | 2007-11-02 | | 公開日 | 2008-04-08 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae
Antimicrob.Agents Chemother., 52, 2008
|
|
2ZC3
 | | Penicillin-binding protein 2X (PBP 2X) acyl-enzyme complex (biapenem) from Streptococcus pneumoniae | | 分子名称: | (4R,5S)-3-(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-ylsulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-meth yl-4,5-dihydro-1H-pyrrole-2-carboxylate, Penicillin-binding protein 2X, SULFATE ION | | 著者 | Yamada, M, Watanabe, T, Takeuchi, Y. | | 登録日 | 2007-11-02 | | 公開日 | 2008-04-08 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae
Antimicrob.Agents Chemother., 52, 2008
|
|
3DWK
 | |
3EQU
 | | Crystal structure of penicillin-binding protein 2 from Neisseria gonorrhoeae | | 分子名称: | GLYCEROL, Penicillin-binding protein 2, SULFATE ION | | 著者 | Powell, A.J, Deacon, A.M, Nicholas, R.A, Davies, C. | | 登録日 | 2008-10-01 | | 公開日 | 2008-10-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance.
J.Biol.Chem., 284, 2009
|
|
3EQV
 | | Crystal structure of penicillin-binding protein 2 from Neisseria gonorrhoeae containing four mutations associated with penicillin resistance | | 分子名称: | GLYCEROL, Penicillin-binding protein 2, SULFATE ION | | 著者 | Powell, A.J, Deacon, A.M, Nicholas, R.A, Davies, C. | | 登録日 | 2008-10-01 | | 公開日 | 2008-10-21 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance.
J.Biol.Chem., 284, 2009
|
|
2RL3
 | | Crystal structure of the OXA-10 W154H mutant at pH 7 | | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase PSE-2, GLYCEROL, ... | | 著者 | Vercheval, L, Kerff, F, Herman, R, Sauvage, E, Guiet, R, Charlier, P, Frere, J.-M, Galleni, M. | | 登録日 | 2007-10-18 | | 公開日 | 2008-10-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases.
Biochemistry, 48, 2009
|
|
2WAF
 | | PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN R6) | | 分子名称: | CHLORIDE ION, PENICILLIN-BINDING PROTEIN 2B | | 著者 | Contreras-Martel, C, Dahout-Gonzalez, C, Dos-Santos-Martins, A, Kotnik, M, Dessen, A. | | 登録日 | 2009-02-05 | | 公開日 | 2009-02-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | | 主引用文献 | Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci
J.Mol.Biol., 387, 2009
|
|
2WAE
 | | PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204) | | 分子名称: | PENICILLIN-BINDING PROTEIN 2B, ZINC ION | | 著者 | Contreras-Martel, C, Dahout-Gonzalez, C, Dos-Santos-Martins, A, Kotnik, M, Dessen, A. | | 登録日 | 2009-02-05 | | 公開日 | 2009-02-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci
J.Mol.Biol., 387, 2009
|
|
2WAD
 | | PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204) | | 分子名称: | PENICILLIN-BINDING PROTEIN 2B, ZINC ION | | 著者 | Contreras-Martel, C, Dahout-Gonzalez, C, Dos-Santos-Martins, A, Kotnik, M, Dessen, A. | | 登録日 | 2009-02-05 | | 公開日 | 2009-02-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci
J.Mol.Biol., 387, 2009
|
|
3FWL
 | | Crystal Structure of the Full-Length Transglycosylase PBP1b from Escherichia coli | | 分子名称: | MOENOMYCIN, Penicillin-binding protein 1B | | 著者 | Sung, M.T, Lai, Y.T, Huang, C.Y, Chou, L.Y, Wong, C.H, Ma, C. | | 登録日 | 2009-01-19 | | 公開日 | 2009-06-02 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.086 Å) | | 主引用文献 | Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
