2WAF

PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN R6)

Summary for 2WAF

Entry DOI	10.2210/pdb2waf/pdb
Related	2WAD 2WAE
Descriptor	PENICILLIN-BINDING PROTEIN 2B, CHLORIDE ION (3 entities in total)
Functional Keywords	peptidoglycan synthesis, penicillin-binding protein, transmembrane, antibiotic resistance, cell shape, peptidoglycan, cell membrane, cell wall biogenesis/degradation, membrane, infection, resistance, antibiotic, peptide binding protein
Biological source	STREPTOCOCCUS PNEUMONIAE
Total number of polymer chains	1
Total formula weight	74281.65
Authors	Contreras-Martel, C.,Dahout-Gonzalez, C.,Dos-Santos-Martins, A.,Kotnik, M.,Dessen, A. (deposition date: 2009-02-05, release date: 2009-02-24, Last modification date: 2023-12-13)
Primary citation	Contreras-Martel, C.,Dahout-Gonzalez, C.,Dos-Santos-Martins, A.,Kotnik, M.,Dessen, A. Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci J.Mol.Biol., 387:899-, 2009 Cited by PubMed: 19233207 DOI: 10.1016/J.JMB.2009.02.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.29 Å)

Structure validation