2WAD

PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204)

Summary for 2WAD

Entry DOI	10.2210/pdb2wad/pdb
Related	2WAE 2WAF
Descriptor	PENICILLIN-BINDING PROTEIN 2B, ZINC ION (3 entities in total)
Functional Keywords	peptidoglycan synthesis, penicillin-binding protein, transmembrane, antibiotic resistance, cell shape, peptidoglycan, cell membrane, cell wall biogenesis/degradation, membrane, infection, resistance, antibiotic, peptide binding protein
Biological source	STREPTOCOCCUS PNEUMONIAE
Cellular location	Cell membrane; Single-pass membrane protein (By similarity): P0A3M6
Total number of polymer chains	3
Total formula weight	222035.21
Authors	Contreras-Martel, C.,Dahout-Gonzalez, C.,Dos-Santos-Martins, A.,Kotnik, M.,Dessen, A. (deposition date: 2009-02-05, release date: 2009-02-24, Last modification date: 2014-02-19)
Primary citation	Contreras-Martel, C.,Dahout-Gonzalez, C.,Dos-Santos-Martins, A.,Kotnik, M.,Dessen, A. Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci J.Mol.Biol., 387:899-, 2009 Cited by PubMed: 19233207 DOI: 10.1016/J.JMB.2009.02.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.18 Å)

Structure validation