2ZC3
Penicillin-binding protein 2X (PBP 2X) acyl-enzyme complex (biapenem) from Streptococcus pneumoniae
Summary for 2ZC3
Entry DOI | 10.2210/pdb2zc3/pdb |
Related | 2ZC4 2ZC5 2ZC6 |
Descriptor | Penicillin-binding protein 2X, (4R,5S)-3-(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium-6-ylsulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-meth yl-4,5-dihydro-1H-pyrrole-2-carboxylate, SULFATE ION, ... (6 entities in total) |
Functional Keywords | peptidoglycan synthesis, cell wall, penicillin-binding, antibiotics, biapenem, antibiotic resistance, cell cycle, cell division, cell shape, cell wall biogenesis/degradation, membrane, secreted, transmembrane, biosynthetic protein |
Biological source | Streptococcus pneumoniae More |
Cellular location | Cell membrane; Single-pass membrane protein: P59676 P59676 P59676 |
Total number of polymer chains | 6 |
Total formula weight | 149162.95 |
Authors | Yamada, M.,Watanabe, T.,Takeuchi, Y. (deposition date: 2007-11-02, release date: 2008-04-08, Last modification date: 2023-11-01) |
Primary citation | Yamada, M.,Watanabe, T.,Baba, N.,Takeuchi, Y.,Ohsawa, F.,Gomi, S. Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae Antimicrob.Agents Chemother., 52:2053-2060, 2008 Cited by PubMed: 18391040DOI: 10.1128/AAC.01456-07 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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