2ZC3

Penicillin-binding protein 2X (PBP 2X) acyl-enzyme complex (biapenem) from Streptococcus pneumoniae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008658	molecular_function	penicillin binding
B	0008658	molecular_function	penicillin binding
D	0008658	molecular_function	penicillin binding
E	0008658	molecular_function	penicillin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 901

Chain	Residue
E	THR425
E	ARG426
F	ARG654

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site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE BMG B 801

Chain	Residue
B	LYS547
B	SER548
B	GLY549
B	THR550
D	LEU203
D	LYS211
B	SER337
B	TRP374
B	SER395
B	ASN397
B	PHE450
B	THR526

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site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE BMG E 801

Chain	Residue
B	GLU320
E	SER337
E	TRP374
E	SER395
E	ASN397
E	GLN452
E	LYS547
E	SER548
E	GLY549
E	THR550

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Acyl-ester intermediate => ECO:0000250|UniProtKB:P0AD65

Chain	Residue	Details
B	SER337
E	SER337

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1m6k

Chain	Residue	Details
B	SER337

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site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1m6k

Chain	Residue	Details
E	SER337

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