1PSJ
 
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1PP2
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1PSH
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1Q7A
 | | Crystal structure of the complex formed between russell's viper phospholipase A2 and an antiinflammatory agent oxyphenbutazone at 1.6A resolution | | 分子名称: | 4-BUTYL-1-(4-HYDROXYPHENYL)-2-PHENYLPYRAZOLIDINE-3,5-DIONE, METHANOL, Phospholipase A2 VRV-PL-VIIIa, ... | | 著者 | Singh, N, Jabeen, T, Sharma, S, Singh, T.P. | | 登録日 | 2003-08-17 | | 公開日 | 2004-05-11 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Phospholipase A2 as a target protein for nonsteroidal anti-inflammatory drugs (NSAIDS): crystal structure of the complex formed between phospholipase A2 and oxyphenbutazone at 1.6 A resolution.
Biochemistry, 43, 2004
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5Y5E
 | | Crystal structure of phospholipase A2 with inhibitor | | 分子名称: | 2-[2-methyl-3-oxamoyl-1-[[2-(trifluoromethyl)phenyl]methyl]indol-4-yl]oxyethanoic acid, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | 著者 | Hou, S, Xu, J, Xu, T, Liu, J. | | 登録日 | 2017-08-08 | | 公開日 | 2018-06-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2group IIE
Sci Rep, 7, 2017
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2H8I
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3OSH
 | | Crystal Structure of The Complex of Group 1 Phospholipase A2 With Atropin At 1.5 A Resolution | | 分子名称: | (1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE, CALCIUM ION, Phospholipase A2 isoform 3 | | 著者 | Shukla, P.K, Kaushik, S, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2010-09-09 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure of The Complex of Group 1 Phospholipase A2 With Atropin At 1.5 A Resolution
To be Published
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2ZBH
 | | Crystal structure of the complex of phospholipase A2 with Bavachalcone from Aerva lanata at 2.6 A resolution | | 分子名称: | (2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one, Phospholipase A2 VRV-PL-VIIIa | | 著者 | Kumar, S, Damodar, N.C, Jain, R, Singh, N, Sharma, S, Kaur, P, Haridas, M, Srinivasan, A, Singh, T.P. | | 登録日 | 2007-10-20 | | 公開日 | 2007-11-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the complex of phospholipase A2 with Bavachalcone from Aerva lanata at 2.6 A resolution
To be Published
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2WQ5
 | | Non-antibiotic properties of tetracyclines: structural basis for inhibition of secretory phospholipase A2. | | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, CALCIUM ION, PHOSPHOLIPASE A2, ... | | 著者 | Dalm, D, Palm, G.J, Hinrichs, W. | | 登録日 | 2009-08-13 | | 公開日 | 2010-03-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Non-Antibiotic Properties of Tetracyclines: Structural Basis for Inhibition of Secretory Phospholipase A(2).
J.Mol.Biol., 398, 2010
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2FNX
 | | Design of Specific Peptide Inhibitors of Phospholipase A2 (PLA2): Crystal Structure of the Complex of PLA2 with a Highly Potent Peptide Val-Ile-Ala-Lys at 2.7A Resolution | | 分子名称: | Inhibitor peptide, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | | 著者 | Singh, N, Srivastava, P, Sharma, S, Dey, S, Singh, T.P. | | 登録日 | 2006-01-11 | | 公開日 | 2006-01-24 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Design of Specific Peptide Inhibitors of Phospholipase A2 (PLA2): Crystal Structure of the Complex of PLA2 with a Highly Potent Peptide Val-Ile-Ala-Lys at 2.7A Resolution
To be Published
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2I0U
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3P2P
 | | ENHANCED ACTIVITY AND ALTERED SPECIFICITY OF PHOSPHOLIPASE A2 BY DELETION OF A SURFACE LOOP | | 分子名称: | CALCIUM ION, PHOSPHOLIPASE A2 | | 著者 | Dijkstra, B.W, Thunnissen, M.M.G.M, Kalk, K.H, Drenth, J. | | 登録日 | 1989-11-29 | | 公開日 | 1990-01-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Enhanced activity and altered specificity of phospholipase A2 by deletion of a surface loop.
Science, 244, 1989
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2H4C
 | | Structure of Daboiatoxin (heterodimeric PLA2 venom) | | 分子名称: | Phospholipase A2-II, Phospholipase A2-III | | 著者 | Gopalan, G, Thwin, M.M, Gopalakrishnakone, P, Swaminathan, K. | | 登録日 | 2006-05-24 | | 公開日 | 2007-05-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and pharmacological comparison of daboiatoxin from Daboia russelli siamensis with viperotoxin F and vipoxin from other vipers.
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
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3Q4Y
 | | Crystal structure of group I phospholipase A2 at 2.3 A resolution in 40% ethanol revealed the critical elements of hydrophobicity of the substrate-binding site | | 分子名称: | CALCIUM ION, ETHANOL, Phospholipase A2 isoform 3 | | 著者 | Shukla, P.K, Kaushik, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2010-12-26 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of group I phospholipase A2 at 2.3 A resolution in 40% ethanol revealed the critical elements of hydrophobicity of the substrate-binding site
To be Published
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6B83
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3QLM
 | | Crystal structure of porcine pancreatic phospholipase A2 in complex with n-hexadecanoic acid | | 分子名称: | CALCIUM ION, PALMITIC ACID, Phospholipase A2, ... | | 著者 | Aparna, V, Dileep, K.V, Karthe, P, Mandal, P.K, Sadasivan, C, Haridas, M. | | 登録日 | 2011-02-03 | | 公開日 | 2011-04-06 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Anti-inflammatory property of n-hexadecanoic acid: Structural evidence and Kinetic assessment.
Chem.Biol.Drug Des., 2012
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6B84
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2ZP3
 | | Carboxylic ester hydrolase, single mutant d49n of bovine pancreatic pla2 enzyme | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | 著者 | Kanaujia, S.P, Sekar, K. | | 登録日 | 2008-06-27 | | 公開日 | 2008-11-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures and molecular-dynamics studies of three active-site mutants of bovine pancreatic phospholipase A(2)
Acta Crystallogr.,Sect.D, 64, 2008
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2ZP5
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6B81
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2GNS
 | | Design of specific peptide inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II phospholipase A2 and a designed pentapeptide Ala- Leu- Val- Tyr- Lys at 2.3 A resolution | | 分子名称: | ALVYK, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | | 著者 | Singh, N, Sharma, S, Somvanshi, R.K, Dey, S, Singh, T.P. | | 登録日 | 2006-04-11 | | 公開日 | 2006-04-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Design of specific peptide inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II phospholipase A2 and a designed pentapeptide Ala - Leu - Val - Tyr - Lys at 2.3 A resolution
To be Published
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3QNL
 | | Crystal structure of PrTX-I complexed to Rosmarinic Acid | | 分子名称: | (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ISOPROPYL ALCOHOL, ... | | 著者 | dos Santos, J.I, Fontes, M.R.M. | | 登録日 | 2011-02-08 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA(2) Inhibition.
Plos One, 6, 2011
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6AL3
 | | Lys49 PLA2 BPII derived from the venom of Protobothrops flavoviridis. | | 分子名称: | Basic phospholipase A2 BP-II, SULFATE ION | | 著者 | Matsui, T, Kamata, S, Suzuki, A, Oda-Ueda, N, Ogawa, T, Tanaka, Y. | | 登録日 | 2018-09-05 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | SDS-induced oligomerization of Lys49-phospholipase A2from snake venom.
Sci Rep, 9, 2019
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6B80
 | | Crystal structure of myotoxin II from Bothrops moojeni complexed to myristic acid | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Basic phospholipase A2 homolog 2, MYRISTIC ACID, ... | | 著者 | Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M. | | 登録日 | 2017-10-05 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | | 主引用文献 | Structural evidence for a fatty acid-independent myotoxic mechanism for a phospholipase A2-like toxin.
Biochim Biophys Acta Proteins Proteom, 1866, 2018
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3R0L
 | | Crystal structure of crotoxin | | 分子名称: | ACETATE ION, CHLORIDE ION, Crotoxin chain A, ... | | 著者 | Saul, F.A, Faure, G. | | 登録日 | 2011-03-08 | | 公開日 | 2011-10-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Crystal Structure of Crotoxin Reveals Key Residues Involved in the Stability and Toxicity of This Potent Heterodimeric Beta-Neurotoxin
J.Mol.Biol., 412, 2011
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