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2GNS

Design of specific peptide inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II phospholipase A2 and a designed pentapeptide Ala- Leu- Val- Tyr- Lys at 2.3 A resolution

Summary for 2GNS
Entry DOI10.2210/pdb2gns/pdb
Related1SV3 1TJ9
DescriptorPhospholipase A2 VRV-PL-VIIIa, ALVYK, SULFATE ION, ... (4 entities in total)
Functional Keywordspeptide inhibitor, binding constant, hydrolase
Biological sourceDaboia russellii pulchella
More
Cellular locationSecreted: P59071
Total number of polymer chains2
Total formula weight14319.57
Authors
Singh, N.,Sharma, S.,Somvanshi, R.K.,Dey, S.,Singh, T.P. (deposition date: 2006-04-11, release date: 2006-04-25, Last modification date: 2023-10-25)
Primary citationSingh, N.,Sharma, S.,Somvanshi, R.K.,Dey, S.,Singh, T.P.
Design of specific peptide inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II phospholipase A2 and a designed pentapeptide Ala - Leu - Val - Tyr - Lys at 2.3 A resolution
To be Published,
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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