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5AZZ
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Crystal structure of seleno-insulin
分子名称: Insulin A chain, Insulin B chain
著者Watanabe, S, Okumura, M, Arai, K, Takei, T, Asahina, Y, Hojo, H, Iwaoka, M, Inaba, K.
登録日2015-10-23
公開日2017-05-03
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Preparation of Selenoinsulin as a Long-Lasting Insulin Analogue.
Angew. Chem. Int. Ed. Engl., 56, 2017
5BTS
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BU of 5bts by Molmil
Structural and biophysical characterization of a covalent insulin dimer formed during storage of neutral formulation of human insulin
分子名称: Insulin A chain, Insulin B chain
著者Norrman, M, Hjorth, C.F.
登録日2015-06-03
公開日2016-03-09
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin.
J.Pharm.Sci., 105, 2016
3Q6E
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BU of 3q6e by Molmil
Human insulin in complex with cucurbit[7]uril
分子名称: Insulin A chain, Insulin B chain, cucurbit[7]uril
著者Chinai, J.M, Taylor, A.B, Hargreaves, N.D, Ryno, L.M, Morris, C.A, Hart, P.J, Urbach, A.R.
登録日2010-12-31
公開日2011-04-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Molecular recognition of insulin by a synthetic receptor.
J.Am.Chem.Soc., 133, 2011
3P2X
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BU of 3p2x by Molmil
Insulin fibrillation is the Janus face of induced fit. A chiaral clamp stabilizes the native state at the expense of activity
分子名称: CHLORIDE ION, Insulin, PHENOL, ...
著者Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A.
登録日2010-10-04
公開日2011-11-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity
To be Published
3P33
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BU of 3p33 by Molmil
Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity
分子名称: CHLORIDE ION, Insulin, PHENOL, ...
著者Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A.
登録日2010-10-04
公開日2011-11-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity
To be Published
3AIY
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BU of 3aiy by Molmil
R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, REFINED AVERAGE STRUCTURE
分子名称: PHENOL, PROTEIN (INSULIN)
著者O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J.
登録日1998-12-29
公開日2000-02-28
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure.
J.Biomol.NMR, 16, 2000
3ROV
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BU of 3rov by Molmil
Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
分子名称: CHLORIDE ION, Insulin, PHENOL, ...
著者Weiss, M.A, Wan, Z.L, Dodson, E.J, Liu, M, Xu, B, Hua, Q.X, Turkenburg, M, Whittingham, J, Nakagawa, S.H, Huang, K, Hu, S.Q, Jia, W.H, Wang, S.H, Brange, J, Whittaker, J, Arvan, P, Katsoyannis, P.G, Dodson, G.G.
登録日2011-04-26
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
To be Published
3BXQ
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The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition
分子名称: ZINC ION, insulin A chain, insulin B chain
著者Wan, Z.L, Huang, K, Hu, S.Q, Whittaker, J, Weiss, M.A.
登録日2008-01-14
公開日2008-05-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition.
J.Biol.Chem., 283, 2008
8SBD
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BU of 8sbd by Molmil
Cryo-EM structure of insulin amyloid-like fibril that is composed of two antiparallel protofilaments
分子名称: Insulin A chain, Insulin B chain
著者Wang, L.W, Hall, C, Uchikawa, E, Chen, D.L, Choi, E, Zhang, X.W, Bai, X.C.
登録日2023-04-03
公開日2023-08-30
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of insulin fibrillation.
Sci Adv, 9, 2023
7QAC
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The T2 structure of polycrystalline cubic human insulin
分子名称: Insulin A chain, Insulin B chain
著者Karavassili, F, Triandafillidis, D.P, Valmas, A, Spiliopoulou, M, Fili, S, Kontou, P, Bowler, M.W, Von Dreele, R.B, Fitch, A, Margiolaki, I.
登録日2021-11-16
公開日2023-06-21
最終更新日2024-02-07
実験手法POWDER DIFFRACTION (2.29 Å)
主引用文献The T 2 structure of polycrystalline cubic human insulin.
Acta Crystallogr D Struct Biol, 79, 2023
7RKD
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BU of 7rkd by Molmil
X-Ray structure of Insulin Analog GLULISINE
分子名称: Insulin B chain analog, Insulin chain A, ZINC ION
著者Reyes-Grajeda, J.P.
登録日2021-07-22
公開日2022-07-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Insulin ANALOGS
To Be Published
6Z7Y
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BU of 6z7y by Molmil
Human insulin in complex with the analytical antibody OXI-005 Fab
分子名称: Insulin, OXI-005 Fab Heavy chain, OXI-005 Fab Light chain
著者Johansson, E.
登録日2020-06-02
公開日2020-12-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties.
Protein Sci., 30, 2021
6Z7Z
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BU of 6z7z by Molmil
Porcine insulin in complex with the analytical antibody OXI-005 Fab
分子名称: Insulin, MAGNESIUM ION, OXI-005 Fab Heavy chain, ...
著者Johansson, E.
登録日2020-06-02
公開日2020-12-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties.
Protein Sci., 30, 2021
5L3N
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BU of 5l3n by Molmil
D11 bound [N29, S39_PQ]-IGF-II
分子名称: Insulin-like growth factor II
著者Hexnerova, R.
登録日2016-05-23
公開日2016-08-10
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
J.Biol.Chem., 291, 2016
5L3L
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BU of 5l3l by Molmil
D11 bound IGF-II
分子名称: Insulin-like growth factor II
著者Hexnerova, R.
登録日2016-05-23
公開日2016-08-10
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
J.Biol.Chem., 291, 2016
5L3M
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BU of 5l3m by Molmil
D11 bound [S39_PQ]-IGF-II
分子名称: Insulin-like growth factor II
著者Hexnerova, R.
登録日2016-05-23
公開日2016-08-10
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
J.Biol.Chem., 291, 2016
6Z7W
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BU of 6z7w by Molmil
Human insulin in complex with the analytical antibody HUI-018 Fab
分子名称: HUI-018 Fab Heavy Chain, Insulin, MAb 6H10 light chain
著者Johansson, E.
登録日2020-06-02
公開日2020-12-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties.
Protein Sci., 30, 2021
8RVT
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BU of 8rvt by Molmil
Structure of full-length human insulin fibrils
分子名称: Insulin A chain, Insulin B chain
著者Bardiaux, B, Suladze, S, Reif, B.
登録日2024-02-02
公開日2024-05-29
最終更新日2024-06-12
実験手法SOLID-STATE NMR
主引用文献Atomic resolution structure of full-length human insulin fibrils.
Proc.Natl.Acad.Sci.USA, 121, 2024
6ZHB
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BU of 6zhb by Molmil
3D electron diffraction structure of bovine insulin
分子名称: Insulin, ZINC ION
著者Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Bacia-Verloop, M, Zander, U, McCarthy, A.A, Schoehn, G, Ling, W.L, Abrahams, J.P.
登録日2020-06-22
公開日2021-01-27
最終更新日2024-01-24
実験手法ELECTRON CRYSTALLOGRAPHY (3.25 Å)
主引用文献Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
6ZI8
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BU of 6zi8 by Molmil
X-ray diffraction structure of bovine insulin at 2.3 A resolution
分子名称: CHLORIDE ION, Insulin, ZINC ION
著者Housset, D, Ling, W.L, Bacia-Verloop, M, Zander, U, McCarthy, A.A, Schoehn, G.
登録日2020-06-25
公開日2021-01-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
7S4Y
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BU of 7s4y by Molmil
Serial Macromolecular Crystallography at ALBA Synchrotron Light Source - Insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Martin-Garcia, J.M, Botha, S, Hu, H, Jernigan, R, Castellvi, A, Lisova, S, Gil, F, Calisto, B, Crespo, I, Roy-Chowdbury, S, Grieco, A, Ketawala, G, Weierstall, U, Spence, J, Fromme, P, Zatsepin, N, Boer, R, Carpena, X.
登録日2021-09-09
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Serial macromolecular crystallography at ALBA Synchrotron Light Source.
J.Synchrotron Radiat., 29, 2022
7QGF
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Cubic Insulin SAD phasing at 14.2 keV
分子名称: Insulin A chain, Insulin B chain
著者Nanao, M.H, Basu, S.
登録日2021-12-08
公開日2022-06-01
実験手法X-RAY DIFFRACTION (1.203 Å)
主引用文献ID23-2: an automated and high-performance microfocus beamline for macromolecular crystallography at the ESRF.
J.Synchrotron Radiat., 29, 2022
5LIS
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BU of 5lis by Molmil
Insulin solved by Native SAD from a dataset collected in one second
分子名称: Insulin
著者Casanas, A, Finke, A, Wang, M.
登録日2016-07-15
公開日2016-08-03
最終更新日2016-09-28
実験手法X-RAY DIFFRACTION (2.293 Å)
主引用文献EIGER detector: application in macromolecular crystallography.
Acta Crystallogr D Struct Biol, 72, 2016
3E7Y
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Structure of human insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Timofeev, V.I, Baidus, A.N, Kislitsyn, Y.A, Kuranova, I.P.
登録日2008-08-19
公開日2009-02-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of human insulin
to be published
5MIZ
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MD ensemble of bovine insulin
分子名称: Insulin
著者Efimov, S.V, Zgadzay, Y.O, Klochkov, V.V.
登録日2016-11-29
公開日2017-01-25
最終更新日2019-05-08
実験手法SOLUTION NMR
主引用文献MD ensemble of bovine insulin
To Be Published

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件を2024-06-12に公開中

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