PDB: 437 件ウェブページステータス検索Chemie searchBIRD

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8HSF	Insulin triple mutant INS-RQD 分子名称: Insulin A chain, Insulin B chain 著者 Kundapura, S.V, Rao, S.S, Kulal, A, Ramagopal, U.A. 登録日 2022-12-19 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insulin triple mutant INS-RQD To Be Published
8HSK	Insulin single mutant INS-Q 分子名称: Insulin A chain, Insulin B chain, SULFATE ION 著者 Rao, S.S, Kundapura, S.V, Kulal, A, Ramagopal, U.A. 登録日 2022-12-19 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Insulin single mutant INS-Q To Be Published
8HGZ	Crystal structure of insulin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 DeMirci, H, Ayan, E. 登録日 2022-11-16 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Comparative Study of High-Resolution LysB29(N epsilon-myristoyl) des(B30) Insulin Structures Display Novel Dynamic Causal Interrelations in Monomeric-Dimeric Motions Crystals, 13, 2023
8IPZ	Crystal structure of insulin detemir 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 DeMirci, H, Ayan, E. 登録日 2023-03-15 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of insulin detemir To Be Published
3BXQ	The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition 分子名称: ZINC ION, insulin A chain, insulin B chain 著者 Wan, Z.L, Huang, K, Hu, S.Q, Whittaker, J, Weiss, M.A. 登録日 2008-01-14 公開日 2008-05-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition. J.Biol.Chem., 283, 2008
6GNQ	Monoclinic crystalline form of human insulin, complexed with meta-cresol 分子名称: 1,2-ETHANEDIOL, Insulin, M-CRESOL, ... 著者 Margiolaki, I, Karavassili, F, Valmas, A, Dimarogona, M, Giannopoulou, A.E, Fili, S, Schluckebier, G, Norrman, M, Beckers, D, Fitch, A.N. 登録日 2018-05-31 公開日 2019-06-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Monoclinic crystalline form of human insulin, complexed with meta-cresol To Be Published
3MTH	X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL 分子名称: 4-HYDROXY-BENZOIC ACID METHYL ESTER, CHLORIDE ION, METHYLPARABEN INSULIN, ... 著者 Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. 登録日 1995-09-13 公開日 1996-01-29 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
6GV0	Insulin glulisine 分子名称: FORMIC ACID, Insulin, ZINC ION 著者 Chayen, N.E, Helliwell, J.R, Solomon-Gamsu, H.V, Govada, L, Morgan, M, Gillis, R.B, Adams, G. 登録日 2018-06-20 公開日 2019-07-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques. Sci Rep, 11, 2021
2ZPP	Neutron crystal structure of cubic insulin at pD9 分子名称: Insulin A chain, Insulin B chain 著者 Ishikawa, T, Tanaka, I, Niimura, N. 登録日 2008-07-26 公開日 2008-10-28 最終更新日 2023-11-01 実験手法 NEUTRON DIFFRACTION (2.5 Å) 主引用文献 An abnormal pK(a) value of internal histidine of the insulin molecule revealed by neutron crystallographic analysis Biochem.Biophys.Res.Commun., 376, 2008
3AIY	R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, REFINED AVERAGE STRUCTURE 分子名称: PHENOL, PROTEIN (INSULIN) 著者 O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. 登録日 1998-12-29 公開日 2000-02-28 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure. J.Biomol.NMR, 16, 2000
3P2X	Insulin fibrillation is the Janus face of induced fit. A chiaral clamp stabilizes the native state at the expense of activity 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. 登録日 2010-10-04 公開日 2011-11-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity To be Published
3P33	Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. 登録日 2010-10-04 公開日 2011-11-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity To be Published
5E7W	X-ray Structure of Human Recombinant 2Zn insulin at 0.92 Angstrom 分子名称: ACETATE ION, Insulin, N-PROPANOL, ... 著者 Lisgarten, D.R, Naylor, C.E, Palmer, R.A, Lobley, C.M.C. 登録日 2015-10-13 公開日 2016-10-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (0.9519 Å) 主引用文献 Ultra-high resolution X-ray structures of two forms of human recombinant insulin at 100 K. Chem Cent J, 11, 2017
5EN9	High resolution x-ray crystal structure of isotope-labeled ester-insulin 分子名称: Insulin chain A, Insulin chain B 著者 Mandal, K, Dhayalan, B, Avital-Shmilovici, M, Tokmakoff, A, Kent, S.B.H. 登録日 2015-11-09 公開日 2016-01-13 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystallization of Enantiomerically Pure Proteins from Quasi-Racemic Mixtures: Structure Determination by X-Ray Diffraction of Isotope-Labeled Ester Insulin and Human Insulin. Chembiochem, 17, 2016
5FB6	Room-temperature macromolecular crystallography using a micro-patterned silicon chip with minimal background scattering 分子名称: Insulin Chain A, Insulin Chain B 著者 Roedig, P, Duman, R, Sanchez-Weatherby, J, Vartiainen, I, Burkhardt, A, Warmer, M, David, C, Wagner, A, Meents, A. 登録日 2015-12-14 公開日 2016-06-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 Room-temperature macromolecular crystallography using a micro-patterned silicon chip with minimal background scattering. J.Appl.Crystallogr., 49, 2016
5ENA	Xray crystal structure of isotope-labeled human insulin 分子名称: Insulin chain A, Insulin chain B 著者 Mandal, K, Dhayalan, B, Avital-Shmilovici, M, Tokmakoff, A, Kent, S.B.H. 登録日 2015-11-09 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystallization of Enantiomerically Pure Proteins from Quasi-Racemic Mixtures: Structure Determination by X-Ray Diffraction of Isotope-Labeled Ester Insulin and Human Insulin. Chembiochem, 17, 2016
5EMS	Crystal Structure of an iodinated insulin analog 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Lawrence, M.C, Pandyarajan, V, Wan, Z, Weiss, M.A. 登録日 2015-11-06 公開日 2016-11-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Extending Halogen-based Medicinal Chemistry to Proteins: IODO-INSULIN AS A CASE STUDY. J. Biol. Chem., 291, 2016
3Q6E	Human insulin in complex with cucurbit[7]uril 分子名称: Insulin A chain, Insulin B chain, cucurbit[7]uril 著者 Chinai, J.M, Taylor, A.B, Hargreaves, N.D, Ryno, L.M, Morris, C.A, Hart, P.J, Urbach, A.R. 登録日 2010-12-31 公開日 2011-04-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Molecular recognition of insulin by a synthetic receptor. J.Am.Chem.Soc., 133, 2011
6OR0	Crystal structure of Insulin from Non-merohedrally twinned crystals 分子名称: Insulin chain A, Insulin chain B 著者 Sevvana, M, Ruf, M, Uson, I, Sheldrick, G.M, Herbst-Irmer, R. 登録日 2019-04-29 公開日 2019-12-11 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Non-merohedral twinning: from minerals to proteins. Acta Crystallogr D Struct Biol, 75, 2019
6INS	X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE 分子名称: INSULIN, ZINC ION 著者 Derewenda, U, Derewenda, Z, Dodson, E.J, Dodson, G.G, Bing, X, Markussen, J. 登録日 1992-11-25 公開日 1994-01-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue. J.Mol.Biol., 220, 1991
6P4Z	Structure of gadolinium-caged cobalt (III) insulin hexamer 分子名称: CHLORIDE ION, COBALT (II) ION, GADOLINIUM ATOM, ... 著者 Tran, T.H, Taylor, S.K, Stojanovic, M.N, Tong, L. 登録日 2019-05-29 公開日 2019-06-12 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Insulin Hexamer-Caged Gadolinium Ion as MRI Contrast-o-phore ChemBioChem, 24, 2018
3RTO	Acoustically mounted porcine insulin microcrystals yield an X-ray SAD structure 分子名称: Insulin, ZINC ION 著者 Soares, A.S, Engel, M.A, Stearns, R, Datwani, S, Olechno, J, Ellson, R, Skinner, J.M, Allaire, M, Orville, A.M. 登録日 2011-05-03 公開日 2011-05-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Acoustically Mounted Microcrystals Yield High-Resolution X-ray Structures. Biochemistry, 50, 2011
6JR3	Crystal structure of insulin hexamer fitted into cryo EM density map where each dimer was kept as rigid body 分子名称: Insulin A chain, Insulin B chain 著者 Sengupta, J, Pathak, B.K, Bhakta, S. 登録日 2019-04-02 公開日 2020-04-22 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (14.5 Å) 主引用文献 Resveratrol as a nontoxic excipient stabilizes insulin in a bioactive hexameric form. J.Comput.Aided Mol.Des., 34, 2020
6U46	Solution Structure of a Heat-Resistant Long-Acting Insulin Analog 分子名称: Insulin 著者 Yang, Y, Weiss, M.A. 登録日 2019-08-23 公開日 2020-08-26 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution Structure of a Heat-Resistant Long-Acting Insulin Analog To Be Published
7QGF	Cubic Insulin SAD phasing at 14.2 keV 分子名称: Insulin A chain, Insulin B chain 著者 Nanao, M.H, Basu, S. 登録日 2021-12-08 公開日 2022-06-01 実験手法 X-RAY DIFFRACTION (1.203 Å) 主引用文献 ID23-2: an automated and high-performance microfocus beamline for macromolecular crystallography at the ESRF. J.Synchrotron Radiat., 29, 2022

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