PDB: 5630 件ウェブページステータス検索Chemie searchBIRD

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6IEV	Crystal structure of a designed protein 分子名称: Designed protein 著者 Han, M, Liao, S, Chen, Q, Liu, H. 登録日 2018-09-17 公開日 2019-09-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Selection and analyses of variants of a designed protein suggest importance of hydrophobicity of partially buried sidechains for protein stability at high temperatures. Protein Sci., 28, 2019
6WRX	Crystal structure of computationally designed protein 2DS25.1 in complex with the human Transferrin receptor ectodomain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Abraham, J, Coscia, A, Olal, D, Sahtoe, D.D, Baker, D, Clark, L. 登録日 2020-04-30 公開日 2021-04-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.07 Å) 主引用文献 Transferrin receptor targeting by de novo sheet extension. Proc.Natl.Acad.Sci.USA, 118, 2021
6WRV	Crystal structure of computationally designed protein 3DS18 in complex with the human Transferrin receptor ectodomain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Computationally designed protein 3DS18, ... 著者 Abraham, J, Baker, D, Sahtoe, D.D, Coscia, A, Clark, L, Olal, D. 登録日 2020-04-30 公開日 2021-04-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Transferrin receptor targeting by de novo sheet extension. Proc.Natl.Acad.Sci.USA, 118, 2021
6WRW	Crystal structure of computationally designed protein 2DS25.5 in complex with the human Transferrin receptor ectodomain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Computationally designed protein 2DS25.5, ... 著者 Abraham, J, Coscia, A, Olal, D, Sahtoe, D.D, Baker, D, Clark, L. 登録日 2020-04-30 公開日 2021-04-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Transferrin receptor targeting by de novo sheet extension. Proc.Natl.Acad.Sci.USA, 118, 2021
5J0I	De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity 分子名称: Designed protein 2L6HC3_12 著者 Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. 登録日 2016-03-28 公開日 2016-05-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.202 Å) 主引用文献 De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
5IZS	De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity 分子名称: Designed protein 5L6HC3_1 著者 Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Oberdorfer, G. 登録日 2016-03-25 公開日 2016-05-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
5J0K	De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity 分子名称: designed protein 2L4HC2_23 著者 Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. 登録日 2016-03-28 公開日 2016-05-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
5J0L	De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity 分子名称: designed protein 3L6HC2_2 著者 Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. 登録日 2016-03-28 公開日 2016-07-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
5J0J	De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity 分子名称: designed protein 2L6HC3_6 著者 Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. 登録日 2016-03-28 公開日 2016-05-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.256 Å) 主引用文献 De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
5WLK	De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4EH2 分子名称: Helical Bundle 4EH2, ZINC ION 著者 Zhang, S.-Q, Liu, L, DeGrado, W.F. 登録日 2017-07-27 公開日 2018-01-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles. J. Am. Chem. Soc., 140, 2018
5WLL	De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4DH1 分子名称: GLYCEROL, Helical Bundle 4DH1, ZINC ION 著者 Zhang, S.-Q, Liu, L, DeGrado, W.F. 登録日 2017-07-27 公開日 2018-01-03 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles. J. Am. Chem. Soc., 140, 2018
5WLM	De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4DH2 分子名称: Helical Bundle 4DH2, ZINC ION 著者 Zhang, S.-Q, Liu, L, DeGrado, W.F. 登録日 2017-07-27 公開日 2018-01-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles. J. Am. Chem. Soc., 140, 2018
5TPH	Crystal structure of a de novo designed protein homodimer with curved beta-sheet 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, de novo NTF2 homodimer 著者 Basanta, B, Marcos, E, Oberdorfer, G, Chidyausiku, T.M, Sankaran, B, Baker, D. 登録日 2016-10-20 公開日 2017-01-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Principles for designing proteins with cavities formed by curved beta sheets. Science, 355, 2017
5U35	Crystal structure of a de novo designed protein with curved beta-sheet 分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-METHOXYETHANOL, CHLORIDE ION, ... 著者 Oberdorfer, G, Marcos, E, Basanta, B, Chidyausiku, T.M, Sankaran, B, Zwart, P.H, Baker, D. 登録日 2016-12-01 公開日 2017-01-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Principles for designing proteins with cavities formed by curved beta sheets. Science, 355, 2017
2A3D	SOLUTION STRUCTURE OF A DE NOVO DESIGNED SINGLE CHAIN THREE-HELIX BUNDLE (A3D) 分子名称: PROTEIN (DE NOVO THREE-HELIX BUNDLE) 著者 Walsh, S.T.R, Cheng, H, Bryson, J.W, Roder, H, Degrado, W.F. 登録日 1999-04-01 公開日 1999-05-05 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure and dynamics of a de novo designed three-helix bundle protein. Proc.Natl.Acad.Sci.USA, 96, 1999
6VTW	De novo protein design enables the precise induction of RSV-neutralizing antibodies 分子名称: 101F Fab Heavy Chain, 101F Fab Light Chain, S4_2.45 著者 Jardetzky, T, Correia, B. 登録日 2020-02-13 公開日 2020-04-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 De novo protein design enables the precise induction of RSV-neutralizing antibodies. Science, 368, 2020
6WA0	De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release 分子名称: De novo designed receptor transmembrane domain proMP C3.1 著者 Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R. 登録日 2020-03-24 公開日 2021-03-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.484 Å) 主引用文献 De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release To Be Published
1VJQ	Designed protein based on backbone conformation of procarboxypeptidase-A (1AYE) with sidechains chosen for maximal predicted stability. 分子名称: designed protein 著者 Merritt, E.A, Baker, D, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) 登録日 2004-03-19 公開日 2004-03-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.098 Å) 主引用文献 Designed protein based on backbone conformation of procarboxypeptidase-A (1AYE) with sidechains chosen for maximal predicted stability. To be Published
8JU8	de novo designed protein 分子名称: de novo designed protein 著者 Zhang, L. 登録日 2023-06-25 公開日 2023-07-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 de novo designed Rossmann fold protein To Be Published
6YQX	Crystal structure of DeNovoTIM13, a de novo designed TIM barrel 分子名称: CHLORIDE ION, GLYCEROL, de novo designed TIM barrel DeNovoTIM13 著者 Romero-Romero, S, Kordes, S, Shanmugaratnam, S, Fernandez-Velasco, D.A, Hocker, B. 登録日 2020-04-18 公開日 2021-07-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.638 Å) 主引用文献 The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach. J.Mol.Biol., 433, 2021
8DZ8	Neoleukin 4, a de novo designed IL-4 mimetic 分子名称: neoleukin-4 著者 Jude, K.M, Spangler, J.B, Garcia, K.C. 登録日 2022-08-06 公開日 2023-03-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.972 Å) 主引用文献 Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds. Nat.Chem.Biol., 19, 2023
5JG9	Crystal structure of the de novo mini protein gEHEE_06 分子名称: CHLORIDE ION, GLYCEROL, de novo design, ... 著者 Rupert, P.B, Johnsen, W.A. 登録日 2016-04-19 公開日 2016-09-28 最終更新日 2016-11-02 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Accurate de novo design of hyperstable constrained peptides. Nature, 538, 2016
6DS9	Elongated version of a de novo designed three helix bundle structure (GRa3D) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, THIOCYANATE ION, ... 著者 Koebke, K.J, Ruckthong, L.R, Meagher, J.L, Stuckey, J.A, Pecoraro, V.L. 登録日 2018-06-13 公開日 2018-10-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Clarifying the Copper Coordination Environment in a de Novo Designed Red Copper Protein. Inorg Chem, 57, 2018
8H7C	Crystal structure of a de novo enzyme, ferric enterobactin esterase Syn-F4 (K4T) - Pt derivative 分子名称: ACETATE ION, CHLORIDE ION, De novo ferric enterobactin esterase Syn-F4, ... 著者 Kurihara, K, Umezawa, K, Donnelly, A.E, Hecht, M.H, Arai, R. 登録日 2022-10-19 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure and activity of a de novo enzyme, ferric enterobactin esterase Syn-F4. Proc.Natl.Acad.Sci.USA, 120, 2023
8H7D	Crystal structure of a de novo enzyme, ferric enterobactin esterase Syn-F4 (K4T) 分子名称: ACETATE ION, De novo ferric enterobactin esterase Syn-F4 著者 Kurihara, K, Umezawa, K, Donnelly, A.E, Hecht, M.H, Arai, R. 登録日 2022-10-19 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure and activity of a de novo enzyme, ferric enterobactin esterase Syn-F4. Proc.Natl.Acad.Sci.USA, 120, 2023

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