PDB: 8861 件ウェブページステータス検索Chemie searchBIRD

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7XQV	The complex of nanobody Rh57 binding to GTP-bound RhoA active form 分子名称: ALANINE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Zhang, Y.R, Liu, R, Ding, Y. 登録日 2022-05-09 公開日 2022-07-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Structural insights into the binding of nanobody Rh57 to active RhoA-GTP. Biochem.Biophys.Res.Commun., 616, 2022
6FNC	Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins 分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, CALCIUM ION, ... 著者 Bier, D, Ottann, C. 登録日 2018-02-02 公開日 2018-07-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins. Chemistry, 24, 2018
6FN9	Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins 分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, GLYCEROL, ... 著者 Bier, D, Ottmann, C. 登録日 2018-02-02 公開日 2018-07-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins. Chemistry, 24, 2018
8OY2	Human cyclin-dependent kinase 2 in complex with inhibitor HB-29260 分子名称: (1S,2S,11aS)-1-methoxy-1,4,7,10-tetramethyl-2,9-bis(oxidanyl)-2,11a-dihydrobenzo[b][1,4]benzodioxepine-3,6-dione, Cyclin-dependent kinase 2, GLYCEROL 著者 Kordes, S, Harvey, C.J.B. 登録日 2023-05-03 公開日 2023-11-29 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.618 Å) 主引用文献 Resistance gene-guided genome mining reveals the roseopurpurins as inhibitors of cyclin-dependent kinases. Proc.Natl.Acad.Sci.USA, 120, 2023
8P4Z	Crystal structure of the human CDK7 kinase domain in complex with LDC4297 分子名称: 2-[(3R)-piperidin-3-yl]oxy-8-propan-2-yl-N-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine, Cyclin-dependent kinase 7, GLYCEROL, ... 著者 Laursen, M, Caing-Carlsson, R, Houssari, R, Javadi, A, Kimbung, Y.R, Murina, V, Orozco-Rodriguez, J.M, Svensson, A, Welin, M, Logan, D, Svensson, B, Walse, B. 登録日 2023-05-23 公開日 2023-06-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal structure of the human CDK7 kinase domain in complex with LDC4297 To Be Published
5V4B	Crystal structure of the Skp1-FBXW7-DISC1 complex 分子名称: DISC1 peptide, F-box/WD repeat-containing protein 7, IMIDAZOLE, ... 著者 Li, Y, Baillie, G.S, Hao, B. 登録日 2017-03-08 公開日 2017-09-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system. Mol. Psychiatry, 23, 2018
8OOR	CryoEM Structure INO80core Hexasome complex Rvb core refinement state2 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, ... 著者 Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S. 登録日 2023-04-05 公開日 2023-07-26 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.87 Å) 主引用文献 Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling. Science, 381, 2023
3DFX	Opposite GATA DNA binding 分子名称: DNA (5'-D(*DAP*DAP*DGP*DGP*DTP*DTP*DAP*DTP*DCP*DTP*DCP*DTP*DGP*DAP*DTP*DTP*DTP*DAP*DTP*DC)-3'), DNA (5'-D(*DTP*DTP*DGP*DAP*DTP*DAP*DAP*DAP*DTP*DCP*DAP*DGP*DAP*DGP*DAP*DTP*DAP*DAP*DCP*DC)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ... 著者 Bates, D.L, Kim, G.K, Guo, L, Chen, L. 登録日 2008-06-12 公開日 2008-07-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA. J.Mol.Biol., 381, 2008
8RHZ	Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated conformation - symmetry expanded unneddylated dimer 分子名称: Cullin-9, E3 ubiquitin-protein ligase RBX1, ZINC ION 著者 Hopf, L.V.M, Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. 登録日 2023-12-17 公開日 2024-04-17 最終更新日 2024-07-31 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nat.Struct.Mol.Biol., 31, 2024
1J3H	Crystal structure of apoenzyme cAMP-dependent protein kinase catalytic subunit 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, cAMP-dependent protein kinase, alpha-catalytic subunit 著者 Akamine, P, Madhusudan, Wu, J, Xuong, N.H, Ten Eyck, L.F, Taylor, S.S. 登録日 2003-01-31 公開日 2003-03-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Dynamic Features of cAMP-dependent Protein Kinase Revealed by Apoenzyme Crystal Structure J.Mol.Biol., 327, 2003
8RUU	Fabs derived from bimekizumab in complex with IL-17F 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoblobulin heavy chain, Immunoblobulin light chain, ... 著者 Adams, R, Lawson, A.D.G. 登録日 2024-01-31 公開日 2024-04-24 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Crystal Structure of Bimekizumab Fab Fragment in Complex with IL-17F Provides Molecular Basis for Dual IL-17A and IL-17F Inhibition. J Invest Dermatol., 2024
8RTT	Structure of the formin Cdc12 bound to the barbed end of phalloidin-stabilized F-actin. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... 著者 Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. 登録日 2024-01-29 公開日 2024-04-10 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
8RU2	Structure of the F-actin barbed end bound by formin mDia1 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... 著者 Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. 登録日 2024-01-29 公開日 2024-04-10 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.49 Å) 主引用文献 Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
5SVE	Structure of Calcineurin in complex with NFATc1 LxVP peptide 分子名称: CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ... 著者 Sheftic, S.R, Page, R, Peti, W. 登録日 2016-08-05 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.596 Å) 主引用文献 Investigating the human Calcineurin Interaction Network using the pi LxVP SLiM. Sci Rep, 6, 2016
8ILW	Transcription factor LMX1a homeobox domain in complex with Pitx3 promoter 分子名称: DNA (5'-D(*CP*AP*AP*CP*AP*CP*TP*TP*AP*AP*TP*CP*CP*AP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*TP*GP*GP*AP*TP*TP*AP*AP*GP*TP*GP*TP*T)-3'), LMX1A factor 著者 Lv, M.Q, Lin, L.Q. 登録日 2023-03-04 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.712 Å) 主引用文献 Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain Febs J., 2024
4ACG	GSK3b in complex with inhibitor 分子名称: 2-AMINO-5-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-N-[4-(PYRROLIDIN-1-YLMETHYL)PYRIDIN-3-YL]PYRIDINE-3-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA 著者 Xue, Y, Ormo, M. 登録日 2011-12-15 公開日 2012-05-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
8BZM	FOXK1-ELF1-heterodimer bound to DNA 分子名称: DNA, ETS-related transcription factor Elf-1, Forkhead box protein K1, ... 著者 Morgunova, E, Popov, A, Yin, Y, Taipale, J. 登録日 2022-12-15 公開日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 FOXK1-ELF1_heterodimer bound to DNA To Be Published
8PPR	Structure of the human outer kinetochore KMN network complex 分子名称: Kinetochore protein Spc24, Kinetochore protein Spc25, Kinetochore scaffold 1, ... 著者 Yatskevich, S, Barford, D. 登録日 2023-07-08 公開日 2024-03-20 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of the human outer kinetochore KMN network complex. Nat.Struct.Mol.Biol., 31, 2024
8C28	14-3-3 in complex with PyrinpS208pS242 分子名称: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Pyrin 著者 Lau, R, Ottmann, C, Hann, M. 登録日 2022-12-21 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 14-3-3/Pyrin complex To Be Published
8C30	Crystal structure of 14-3-3 in complex with PyrinpS242 and a protein/peptide interface fragment 分子名称: 14-3-3 protein sigma, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CALCIUM ION, ... 著者 Lau, R, Ottmann, C. 登録日 2022-12-23 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 14-3-3/Pyrin complex To Be Published
8C2Y	14-3-3 in complex with Pyrinp pS242 分子名称: 14-3-3 protein sigma, Pyrin pS242 peptide 著者 Lau, R, Ottmann, C, Hann, M. 登録日 2022-12-23 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 14-3-3/Pyrin complex To Be Published
6FNA	Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins 分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, CALCIUM ION, ... 著者 Bier, D, Ottmann, C. 登録日 2018-02-02 公開日 2018-07-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins. Chemistry, 24, 2018
7D9V	CRTC1 pSer245 peptide in complex with 14-3-3 zeta 分子名称: 14-3-3 protein zeta/delta, CRTC1 pSer245 peptide, GLYCEROL 著者 Chen, H, Zhang, H, Xiang, S. 登録日 2020-10-14 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structural Insights into the Interaction Between CRTCs and 14-3-3. J.Mol.Biol., 433, 2021
7D8P	CRTC1 pSer151 peptide in complex with 14-3-3 zeta 分子名称: 14-3-3 protein zeta/delta, CRTC1 pSer151 peptide, GLYCEROL 著者 Chen, H, Zhang, H, Xiang, S. 登録日 2020-10-08 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Insights into the Interaction Between CRTCs and 14-3-3. J.Mol.Biol., 433, 2021
7D8H	CRTC1 pSer64 peptide in complex with 14-3-3 zeta 分子名称: 14-3-3 protein zeta/delta, CRTC1 pSer64 peptide 著者 Chen, H, Zhang, H, Xiang, S. 登録日 2020-10-08 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Structural Insights into the Interaction Between CRTCs and 14-3-3. J.Mol.Biol., 433, 2021

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