2VEO
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![BU of 2veo by Molmil](/molmil-images/mine/2veo) | X-ray structure of Candida antarctica lipase A in its closed state. | 分子名称: | GLYCEROL, LIPASE A, TETRAETHYLENE GLYCOL, ... | 著者 | Ericsson, D.J, Kasrayan, A, Johansson, P, Bergfors, T, Sandstrom, A.G, Backvall, J.E, Mowbray, S.L. | 登録日 | 2007-10-25 | 公開日 | 2007-11-06 | 最終更新日 | 2015-04-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | X-Ray Structure of Candida Antarctica Lipase a Shows a Novel Lid Structure and a Likely Mode of Interfacial Activation. J.Mol.Biol., 376, 2008
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2VBK
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![BU of 2vbk by Molmil](/molmil-images/mine/2vbk) | NATIVE TAILSPIKE PROTEIN OF BACTERIOPHAGE SF6 | 分子名称: | 1,2-ETHANEDIOL, CARBON DIOXIDE, GLYCEROL, ... | 著者 | Mueller, J.J, Barbirz, S, Heinle, K, Freiberg, A, Seckler, R, Heinemann, U. | 登録日 | 2007-09-14 | 公開日 | 2008-04-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | An intersubunit active site between supercoiled parallel beta helices in the trimeric tailspike endorhamnosidase of Shigella flexneri Phage Sf6. Structure, 16, 2008
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6ZNV
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![BU of 6znv by Molmil](/molmil-images/mine/6znv) | Protein polybromo-1 (PB1 BD2) Bound To DP28 | 分子名称: | 1,2-ETHANEDIOL, 1-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]piperidin-4-ol, ACETATE ION, ... | 著者 | Preuss, F, Mathea, S, Chatterjee, D, Wanior, M, Joerger, A.C, Knapp, S. | 登録日 | 2020-07-06 | 公開日 | 2020-08-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis. J.Med.Chem., 63, 2020
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1YCK
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6ZS2
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![BU of 6zs2 by Molmil](/molmil-images/mine/6zs2) | Crystal Structure of the bromodomain of human transcription activator BRG1 (SMARCA4) in complex with 2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol | 分子名称: | 1,2-ETHANEDIOL, 2-(6-azanyl-5-piperazin-4-ium-1-yl-pyridazin-3-yl)phenol, Transcription activator BRG1 | 著者 | Preuss, F, Joerger, A.C, Kraemer, A, Wanior, M, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2020-07-15 | 公開日 | 2020-10-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis. J.Med.Chem., 63, 2020
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2UWX
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![BU of 2uwx by Molmil](/molmil-images/mine/2uwx) | Active site restructuring regulates ligand recognition in class A penicillin-binding proteins | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, ... | 著者 | Macheboeuf, P, DiGuilmi, A.M, Job, V, Vernet, T, Dideberg, O, Dessen, A. | 登録日 | 2007-03-23 | 公開日 | 2007-04-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Active Site Restructuring Regulates Ligand Recognition in Class a Penicillin-Binding Proteins Proc.Natl.Acad.Sci.USA, 102, 2005
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2Q3Z
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![BU of 2q3z by Molmil](/molmil-images/mine/2q3z) | Transglutaminase 2 undergoes large conformational change upon activation | 分子名称: | Polypeptide, SULFATE ION, Transglutaminase 2 | 著者 | Strop, P, Pinkas, D.M, Brunger, A.T, Khosla, C. | 登録日 | 2007-05-30 | 公開日 | 2007-10-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Transglutaminase 2 undergoes a large conformational change upon activation Plos Biol., 5, 2007
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3L1F
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![BU of 3l1f by Molmil](/molmil-images/mine/3l1f) | Bovine AlphaA crystallin | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin A chain | 著者 | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2009-12-11 | 公開日 | 2010-05-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci., 19, 2010
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1QC9
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2WDZ
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![BU of 2wdz by Molmil](/molmil-images/mine/2wdz) | Crystal structure of the short chain dehydrogenase Galactitol- Dehydrogenase (GatDH) of Rhodobacter sphaeroides in complex with NAD+ and 1,2-Pentandiol | 分子名称: | (2S)-pentane-1,2-diol, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Carius, Y, Christian, H, Faust, A, Kornberger, P, Kohring, G.W, Giffhorn, F, Scheidig, A.J. | 登録日 | 2009-03-27 | 公開日 | 2010-03-31 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Insight Into Substrate Differentiation of the Sugar-Metabolizing Enzyme Galactitol Dehydrogenase from Rhodobacter Sphaeroides D. J.Biol.Chem., 285, 2010
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7YFN
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![BU of 7yfn by Molmil](/molmil-images/mine/7yfn) | Core module of the NuA4 complex in S. cerevisiae | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ARP4 isoform 1, Actin, ... | 著者 | Ji, L.T, Zhao, L.X, Xu, K, Gao, H.H, Zhou, Y, Kornberg, R.D, Zhang, H.Q. | 登録日 | 2022-07-08 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of the NuA4 histone acetyltransferase complex. Proc.Natl.Acad.Sci.USA, 119, 2022
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8BW1
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![BU of 8bw1 by Molmil](/molmil-images/mine/8bw1) | Yeast 20S proteasome in complex with an engineered fellutamide derivative (C14QAL) | 分子名称: | 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Bozhueyuek, K.A.J, Praeve, L, Kegler, C, Kaiser, S, Shi, Y, Kuttenlochner, W, Schenk, L, Groll, M, Hochberg, G.K.A, Bode, H.B. | 登録日 | 2022-12-06 | 公開日 | 2023-12-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Evolution-inspired engineering of nonribosomal peptide synthetases. Science, 383, 2024
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3L1E
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![BU of 3l1e by Molmil](/molmil-images/mine/3l1e) | Bovine AlphaA crystallin Zinc Bound | 分子名称: | Alpha-crystallin A chain, GLYCEROL, ZINC ION | 著者 | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2009-12-11 | 公開日 | 2010-05-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci., 19, 2010
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1QDV
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![BU of 1qdv by Molmil](/molmil-images/mine/1qdv) | N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-131 | 分子名称: | KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL | 著者 | Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Yu, M, Jan, Y.N, Jan, L.Y, Berger, J.M. | 登録日 | 1999-07-10 | 公開日 | 2000-09-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel. Cell(Cambridge,Mass.), 102, 2000
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2W0C
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![BU of 2w0c by Molmil](/molmil-images/mine/2w0c) | X-ray structure of the entire lipid-containing bacteriophage PM2 | 分子名称: | CALCIUM ION, MAJOR CAPSID PROTEIN P2, PROTEIN 2, ... | 著者 | Abrescia, N.G.A, Grimes, J.M, Kivela, H.M, Assenberg, R, Sutton, G.C, Butcher, S.J, Bamford, J.K.H, Bamford, D.H, Stuart, D.I. | 登録日 | 2008-08-13 | 公開日 | 2008-09-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (7 Å) | 主引用文献 | Insights Into Virus Evolution and Membrane Biogenesis from the Structure of the Marine Lipid-Containing Bacteriophage Pm2 Mol.Cell, 31, 2008
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3L4K
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![BU of 3l4k by Molmil](/molmil-images/mine/3l4k) | Topoisomerase II-DNA cleavage complex, metal-bound | 分子名称: | 3'-THIO-THYMIDINE-5'-PHOSPHATE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*CP*GP*TP*CP*AP*TP*CP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), ... | 著者 | Schmidt, B.H, Burgin, A.B, Deweese, J.E, Osheroff, N, Berger, J.M. | 登録日 | 2009-12-20 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases. Nature, 465, 2010
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1YY8
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![BU of 1yy8 by Molmil](/molmil-images/mine/1yy8) | Crystal structure of the Fab fragment from the monoclonal antibody cetuximab/Erbitux/IMC-C225 | 分子名称: | Cetuximab Fab Heavy chain, Cetuximab Fab Light chain | 著者 | Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M. | 登録日 | 2005-02-24 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for inhibition of the epidermal growth factor receptor by cetuximab Cancer Cell, 7, 2005
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5YVH
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1Z19
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![BU of 1z19 by Molmil](/molmil-images/mine/1z19) | Crystal structure of a lambda integrase(75-356) dimer bound to a COC' core site | 分子名称: | 33-MER, 5'-D(*CP*TP*CP*GP*TP*TP*CP*AP*GP*CP*TP*TP*TP*TP*TP*T)-3', 5'-D(P*TP*TP*TP*AP*TP*AP*CP*TP*AP*AP*GP*TP*TP*GP*GP*CP*AP*TP*TP*A)-3', ... | 著者 | Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T. | 登録日 | 2005-03-03 | 公開日 | 2005-06-28 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A structural basis for allosteric control of DNA recombination by lambda integrase. Nature, 435, 2005
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2WQG
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![BU of 2wqg by Molmil](/molmil-images/mine/2wqg) | SAP domain from Tho1: L31W (fluorophore) mutant | 分子名称: | PROTEIN THO1 | 著者 | Dodson, C.A, Ferguson, N, Rutherford, T.J, Johnson, C.M, Fersht, A.R. | 登録日 | 2009-08-21 | 公開日 | 2010-02-16 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Engineering a Two-Helix Bundle Protein for Folding Studies. Protein Eng.Des.Sel., 23, 2010
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7VU3
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![BU of 7vu3 by Molmil](/molmil-images/mine/7vu3) | Chitoporin from Serratia marcescens in-complex with chitohexaose | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Amornloetwattana, R, Robinson, R.C, van den Berg, B, Suginta, W. | 登録日 | 2021-11-01 | 公開日 | 2022-11-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Chitoporin from Serratia marcescens in-complex with chitohexaose To Be Published
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2WHR
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![BU of 2whr by Molmil](/molmil-images/mine/2whr) | Crystal structure of acetylcholinesterase in complex with K027 | 分子名称: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... | 著者 | Ekstrom, F, Hornberg, A, Artursson, E, Hammarstrom, L.-G, Schneider, G, Pang, Y.-P. | 登録日 | 2009-05-06 | 公開日 | 2009-05-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.545 Å) | 主引用文献 | Structure of Hi-6Sarin-Acetylcholinesterase Determined by X-Ray Crystallography and Molecular Dynamics Simulation: Reactivator Mechanism and Design. Plos One, 4, 2009
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8A1E
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![BU of 8a1e by Molmil](/molmil-images/mine/8a1e) | Rabies virus glycoprotein in complex with Fab fragments of 17C7 and 1112-1 neutralizing antibodies | 分子名称: | Fab 1112-1 heavy chain variable domain, Fab 1112-1 light chain variable domain, Fab 17C7 heavy chain variable domain, ... | 著者 | Ng, W.M, Fedosyuk, S, English, S, Augusto, G, Berg, A, Thorley, L, Haselon, A.S, Segireddy, R.R, Bowden, T.A, Douglas, A.D. | 登録日 | 2022-06-01 | 公開日 | 2022-08-17 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structure of trimeric pre-fusion rabies virus glycoprotein in complex with two protective antibodies. Cell Host Microbe, 30, 2022
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7VU2
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![BU of 7vu2 by Molmil](/molmil-images/mine/7vu2) | Chitoporin from Serratia marcescens | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Amornloetwattana, R, Robinson, R.C, van den Berg, B, Suginta, W. | 登録日 | 2021-11-01 | 公開日 | 2022-11-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Chitoporin from Serratia marcescens To Be Published
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3LJR
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![BU of 3ljr by Molmil](/molmil-images/mine/3ljr) | GLUTATHIONE TRANSFERASE (THETA CLASS) FROM HUMAN IN COMPLEX WITH THE GLUTATHIONE CONJUGATE OF 1-MENAPHTHYL SULFATE | 分子名称: | 1-MENAPHTHYL GLUTATHIONE CONJUGATE, GLUTATHIONE S-TRANSFERASE, SULFATE ION | 著者 | Rossjohn, J, Mckinstry, W.J, Oakley, A.J, Verger, D, Flanagan, J, Chelvanayagam, G, Tan, K.L, Board, P.G, Parker, M.W. | 登録日 | 1998-03-08 | 公開日 | 1999-03-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site. Structure, 6, 1998
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