6ZNV

Protein polybromo-1 (PB1 BD2) Bound To DP28

Summary for 6ZNV

• Entry DOI: 10.2210/pdb6znv/pdb
• Related: 6ZN6
• Descriptor: Protein polybromo-1, 1-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]piperidin-4-ol, ZINC ION, ... (7 entities in total)
• Functional Keywords: bromodomain inhibitor epigenetics, protein binding
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 13805.01

Authors

Preuss, F.,Mathea, S.,Chatterjee, D.,Wanior, M.,Joerger, A.C.,Knapp, S. (deposition date: 2020-07-06, release date: 2020-08-26, Last modification date: 2024-01-31)

• Primary citation: Wanior, M.,Preuss, F.,Ni, X.,Kramer, A.,Mathea, S.,Gobel, T.,Heidenreich, D.,Simonyi, S.,Kahnt, A.S.,Joerger, A.C.,Knapp, S.; Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis.; J.Med.Chem., 63:14680-14699, 2020; PubMed: 33216538; DOI: 10.1021/acs.jmedchem.0c01242

Experimental method

X-RAY DIFFRACTION (1.14 Å)