PDB: 66478 件ウェブページステータス検索Chemie searchBIRD

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4S1Y	X-ray structure of human serum albumin complexed with cisplatin 分子名称: Cisplatin, Serum albumin 著者 Merlino, A. 登録日 2015-01-16 公開日 2015-04-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.16 Å) 主引用文献 Cisplatin binding to human serum albumin: a structural study. Chem.Commun.(Camb.), 51, 2015
4RNC	Crystal structure of an esterase RhEst1 from Rhodococcus sp. ECU1013 分子名称: Esterase, PHOSPHATE ION 著者 Dou, S, Kong, X.D, Xu, J.H, Zhou, J. 登録日 2014-10-23 公開日 2015-10-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Substrate channel evolution of an esterase for the synthesis of Cilastatin CATALYSIS SCIENCE AND TECHNOLOGY, 5, 2015
4OOK	Third Metal bound M.tuberculosis methionine aminopeptidase 分子名称: COBALT (II) ION, Methionine aminopeptidase 2, SODIUM ION 著者 Reddi, R, Addlagatta, A. 登録日 2014-02-03 公開日 2015-02-04 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents Febs J., 281, 2014
4OOT	X-ray structure of the protein-gold adduct formed upon reaction of Aubipic with hen egg white lysozyme 分子名称: 1,2-ETHANEDIOL, GOLD ION, Lysozyme C, ... 著者 Merlino, A. 登録日 2014-02-04 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Protein Recognition of Gold-Based Drugs: 3D Structure of the Complex Formed When Lysozyme Reacts with Aubipy(c.). ACS Med Chem Lett, 5, 2014
4OVF	E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid 分子名称: (2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2014-02-21 公開日 2014-03-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015
4K3P	E. coli sliding clamp in complex with AcQLALF 分子名称: (ACE)QLALF, 1,2-ETHANEDIOL, CALCIUM ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-04-11 公開日 2013-05-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4KO7	Investigating the functional significance of the interlocked pair structural determinants in Pseudomonas aeruginosa azurin (V31I/W48F/V95I) 分子名称: Azurin, COPPER (II) ION 著者 Inampudi, K.K, Meng, W, Tobin, P.H, Wilson, C.J. 登録日 2013-05-11 公開日 2014-05-14 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Investigating the functional significance of the interlocked pair structural determinants in Pseudomonas aeruginosa azurin (V31I/W48F/V95I) To be Published
2Z2F	X-ray Crystal Structure of Bovine Stomach Lysozyme 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Lysozyme C-2, SODIUM ION 著者 Akieda, D, Nonaka, Y, Watanabe, N, Tanaka, I, Kamiya, M, Aizawa, T, Nitta, K, Demura, M, Kawano, K. 登録日 2007-05-21 公開日 2008-05-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Stability of Bovine Stomach Lysozyme in Acidic Condition To be Published
2Z5F	Human sulfotransferase Sult1b1 in complex with PAP 分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase family cytosolic 1B member 1 著者 Dombrovski, L, Pegasova, T, Wu, H, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Sundstrom, M, Plotnikov, A.N, Bochkarev, A, Structural Genomics Consortium (SGC) 登録日 2007-07-07 公開日 2007-08-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of human sulfotransferases SULT1B1 and SULT1C1 complexed with the cofactor product adenosine-3'-5'-diphosphate (PAP) Proteins, 64, 2006
3MOU	Characterization of the Inhibitor Binding Site of the Dehaloperoxidase-Hemoglobin from Amphitrite ornata using High-Pressure Xenon Derivatization 分子名称: Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... 著者 de Serrano, V.S, Franzen, S. 登録日 2010-04-23 公開日 2011-04-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.711 Å) 主引用文献 Characterization of the Inhibitor Binding Site of the Dehaloperoxidase-Hemoglobin from Amphitrite ornata using High-Pressure Xenon Derivatization To be Published
4K3R	E. coli sliding clamp in complex with AcQLDLA 分子名称: (ACE)QLDLA, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-04-11 公開日 2013-05-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
2Z2E	Crystal Structure of Canine Milk Lysozyme Stabilized against Non-enzymatic Deamidation 分子名称: Lysozyme C, milk isozyme, SULFATE ION 著者 Nonaka, Y, Akieda, D, Watanabe, N, Tanaka, I, Kamiya, M, Aizawa, T, Nitta, K, Demura, M, Kawano, K. 登録日 2007-05-21 公開日 2007-11-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Spontaneous asparaginyl deamidation of canine milk lysozyme under mild conditions Proteins, 72, 2008
4KJV	Crystal structure of XIAP-Bir2 with a bound spirocyclic benzoxazepinone inhibitor. 分子名称: 6-methoxy-5-({(3S)-3-[(N-methyl-L-alanyl)amino]-4-oxo-2',3,3',4,5',6'-hexahydro-5H-spiro[1,5-benzoxazepine-2,4'-pyran]-5-yl}methyl)naphthalene-2-carboxylic acid, E3 ubiquitin-protein ligase XIAP, ZINC ION 著者 Lukacs, C.M, Janson, C.A. 登録日 2013-05-03 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Optimization of Benzodiazepinones as Selective Inhibitors of the X-Linked Inhibitor of Apoptosis Protein (XIAP) Second Baculovirus IAP Repeat (BIR2) Domain. J.Med.Chem., 56, 2013
3N0D	Crystal structure of WDR5 mutant (W330F) 分子名称: WD repeat-containing protein 5 著者 Wu, Y.-D, Wu, X.-H, Gao, Y, Chen, R.-C. 登録日 2010-05-13 公開日 2010-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Effect of Asp-His-Ser/Thr-Trp Tetrad on the Thermostability of WD40-Repeat Proteins Biochemistry, 49, 2010
3N3G	4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important 分子名称: (E)-1-(6-{4-[3-(4-methylpiperazin-1-yl)propoxy]-3-(trifluoromethyl)phenyl}pyridin-2-yl)methanimine, 6-{4-[3-(4-methylpiperazin-1-yl)propoxy]-3-(trifluoromethyl)phenyl}pyridine-2-carbonitrile, Cathepsin S, ... 著者 Fradera, X, Uitdehaag, J.C.M, van Zeeland, M. 登録日 2010-05-20 公開日 2010-07-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important. Bioorg.Med.Chem.Lett., 20, 2010
3MXX	Crystal structure of WDR5 mutant (S62A) 分子名称: WD repeat-containing protein 5 著者 Wu, Y.-D, Wu, X.-H, Gao, Y, Chen, R.-C. 登録日 2010-05-08 公開日 2010-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The Effect of Asp-His-Ser/Thr-Trp Tetrad on the Thermostability of WD40-Repeat Proteins Biochemistry, 49, 2010
3MX4	DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29KI inactive variant E142Q 分子名称: DNA (5'-D(P*CP*GP*GP*GP*AP*GP*GP*CP*CP*CP*GP*CP*GP*GP*GP*CP*CP*GP*CP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*GP*CP*GP*GP*CP*CP*CP*GP*CP*GP*GP*GP*CP*CP*TP*CP*CP*CP*G)-3'), Eco29kIR 著者 Mak, A.N.S, Lambert, A.R, Stoddard, B.L. 登録日 2010-05-06 公開日 2010-09-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Folding, DNA Recognition, and Function of GIY-YIG Endonucleases: Crystal Structures of R.Eco29kI. Structure, 18, 2010
6RPS	X-ray crystal structure of carbonic anhydrase XII complexed with a theranostic monoclonal antibody fragment 分子名称: ACETATE ION, CADMIUM ION, CHLORIDE ION, ... 著者 Alterio, V, Esposito, D, De Simone, G. 登録日 2019-05-14 公開日 2019-11-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Biochemical and Structural Insights into Carbonic Anhydrase XII/Fab6A10 Complex. J.Mol.Biol., 431, 2019
3N4L	BACE-1 in complex with ELN380842 分子名称: Beta-secretase 1, N-[(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-({1-[3-(1H-pyrazol-1-yl)phenyl]cyclohexyl}amino)propyl]acetamide 著者 Yao, N.H. 登録日 2010-05-21 公開日 2010-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Improving the permeability of the hydroxyethylamine BACE-1 inhibitors: structure-activity relationship of P2' substituents. Bioorg.Med.Chem.Lett., 20, 2010
4LBF	Crystal structure of HUMAN ALPHA-DEFENSIN 1 (HNP1) I20A/L25A mutant 分子名称: GLYCEROL, Neutrophil defensin 1 著者 Tolbert, W.D, Wu, X, Pazgier, M. 登録日 2013-06-20 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function. Plos One, 8, 2013
3N0E	Crystal structure of WDR5 mutant (W330Y) 分子名称: WD repeat-containing protein 5 著者 Wu, Y.-D, Wu, X.-H, Gao, Y, Chen, R.-C. 登録日 2010-05-13 公開日 2010-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Effect of Asp-His-Ser/Thr-Trp Tetrad on the Thermostability of WD40-Repeat Proteins Biochemistry, 49, 2010
4MFF	Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable TTP 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA polymerase beta, MAGNESIUM ION, ... 著者 Koag, M.C, Min, K, Monzingo, A.F, Lee, S. 登録日 2013-08-27 公開日 2014-04-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
4MFC	Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable CTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA polymerase beta, MAGNESIUM ION, ... 著者 Koag, M.C, Min, K, Monzingo, A.F, Lee, S. 登録日 2013-08-27 公開日 2014-04-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
4MGV	Crystal structure of FK506 binding domain of plasmodium VIVAX FKBP35 In complex with inhibitor D5 分子名称: 70 kDa peptidylprolyl isomerase, putative, N'-(1-adamantylcarbonyl)pyridine-4-carbohydrazide 著者 Rajan, S, Harikishore, A, Yoon, H.S. 登録日 2013-08-29 公開日 2013-12-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Adamantyl derivative as a potent inhibitor of Plasmodium FK506 binding protein 35. Acs Med.Chem.Lett., 4, 2013
3N9K	F229A/E292S Double Mutant of Exo-beta-1,3-glucanase from Candida albicans in Complex with Laminaritriose at 1.7 A 分子名称: CALCIUM ION, Glucan 1,3-beta-glucosidase, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose, ... 著者 Nakatani, Y, Cutfield, S.M, Cutfield, J.F. 登録日 2010-05-30 公開日 2010-09-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Carbohydrate binding sites in Candida albicans exo-beta-1,3-glucanase and the role of the Phe-Phe 'clamp' at the active site entrance Febs J., 277, 2010

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