4MFC
Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable CTP
Summary for 4MFC
Entry DOI | 10.2210/pdb4mfc/pdb |
Related | 1BPX 3ISB 4MF2 4MF8 4MFA 4MFF |
Descriptor | DNA polymerase beta, template, up primer, ... (8 entities in total) |
Functional Keywords | dna polymerase x family, dna synthesis, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P06746 |
Total number of polymer chains | 4 |
Total formula weight | 47097.00 |
Authors | Koag, M.C.,Min, K.,Monzingo, A.F.,Lee, S. (deposition date: 2013-08-27, release date: 2014-04-16, Last modification date: 2024-02-28) |
Primary citation | Koag, M.C.,Lee, S. Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136:5709-5721, 2014 Cited by PubMed: 24694247DOI: 10.1021/ja500172d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.13 Å) |
Structure validation
Download full validation report