4MGV

Crystal structure of FK506 binding domain of plasmodium VIVAX FKBP35 In complex with inhibitor D5

Summary for 4MGV

Entry DOI	10.2210/pdb4mgv/pdb
Related	3IHZ 4ITZ 4J4N 4J4O
Descriptor	70 kDa peptidylprolyl isomerase, putative, N'-(1-adamantylcarbonyl)pyridine-4-carbohydrazide (3 entities in total)
Functional Keywords	inhibitor, d5, fkbp, fkbp35, isomerase, fk506
Biological source	Plasmodium vivax
Total number of polymer chains	1
Total formula weight	14271.06
Authors	Rajan, S.,Harikishore, A.,Yoon, H.S. (deposition date: 2013-08-29, release date: 2013-12-04, Last modification date: 2023-11-08)
Primary citation	Harikishore, A.,Leow, M.L.,Niang, M.,Rajan, S.,Pasunooti, K.K.,Preiser, P.R.,Liu, X.,Yoon, H.S. Adamantyl derivative as a potent inhibitor of Plasmodium FK506 binding protein 35. Acs Med.Chem.Lett., 4:1097-1101, 2013 Cited by PubMed: 24900611 DOI: 10.1021/ml400306r PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.72 Å)

Structure validation