4ITZ

Crystal structure of the FK506 binding domain of Plasmodium vivax FKBP35 in complex with a tetrapeptide substrate

Summary for 4ITZ

• Entry DOI: 10.2210/pdb4itz/pdb
• Related: 2KI3 3IHZ 3NI6
• Descriptor: 70 kDa peptidylprolyl isomerase, substrate peptide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: plasmodium vivax, fkbp35, substrate, sucalpfpna, ppiase, isomerase, isomerase-substrate complex, isomerase/substrate
• Biological source: Plasmodium vivax
• Total number of polymer chains: 3
• Total formula weight: 28706.16

Authors

Sreekanth, R.,Yoon, H.S. (deposition date: 2013-01-19, release date: 2013-03-20, Last modification date: 2013-05-22)

• Primary citation: Alag, R.,Balakrishna, A.M.,Rajan, S.,Qureshi, I.A.,Shin, J.,Lescar, J.,Gruber, G.,Yoon, H.S.; Structural insights into substrate binding by PvFKBP35, a peptidylprolyl cis-trans isomerase from the human malarial parasite Plasmodium vivax.; Eukaryot Cell, 12:627-634, 2013; PubMed: 23435727; DOI: 10.1128/EC.00016-13

Experimental method

X-RAY DIFFRACTION (1.65 Å)