PDB: 1302 件ウェブページステータス検索Chemie searchBIRD

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8DJM	HMGCR-UBIAD1 Complex State 1 分子名称: 3-hydroxy-3-methylglutaryl-coenzyme A reductase, CHOLESTEROL HEMISUCCINATE, Digitonin, ... 著者 Chen, H, Qi, X, Li, X. 登録日 2022-07-01 公開日 2022-08-03 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain. Nat Commun, 13, 2022
8DJK	HMGCR-UBIAD1 Complex State 2 分子名称: 3-hydroxy-3-methylglutaryl-coenzyme A reductase, CHOLESTEROL HEMISUCCINATE, Digitonin, ... 著者 Chen, H, Qi, X, Li, X. 登録日 2022-06-30 公開日 2022-08-03 実験手法 ELECTRON MICROSCOPY (3.33 Å) 主引用文献 Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain. Nat Commun, 13, 2022
5T2C	CryoEM structure of the human ribosome at 3.6 Angstrom resolution 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Zhang, X, Lai, M, Zhou, Z.H. 登録日 2016-08-23 公開日 2017-01-25 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes. Nat Commun, 7, 2016
6FEC	Human cap-dependent 48S pre-initiation complex 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Schaffitzel, C, Schaffitzel, C. 登録日 2017-12-31 公開日 2018-03-14 最終更新日 2018-10-03 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Structure of a human cap-dependent 48S translation pre-initiation complex. Nucleic Acids Res., 46, 2018
6Z6M	Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. 登録日 2020-05-28 公開日 2020-07-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
6Z6N	Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1) 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. 登録日 2020-05-28 公開日 2020-07-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
6Y57	Structure of human ribosome in hybrid-PRE state 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. 登録日 2020-02-25 公開日 2020-04-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
5LKS	Structure-function insights reveal the human ribosome as a cancer target for antibiotics 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... 著者 Myasnikov, A.G, Natchiar, S.K, Nebout, M, Hazemann, I, Imbert, V, Khatter, H, Peyron, J.-F, Klaholz, B.P. 登録日 2016-07-23 公開日 2017-04-26 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure-function insights reveal the human ribosome as a cancer target for antibiotics. Nat Commun, 7, 2016
4UG0	STRUCTURE OF THE HUMAN 80S RIBOSOME 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S RIBOSOMAL PROTEIN, ... 著者 Khatter, H, Myasnikov, A.G, Natchiar, S.K, Klaholz, B.P. 登録日 2015-03-20 公開日 2015-06-10 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the human 80S ribosome NATURE, 520, 2015
6ZOJ	SARS-CoV-2-Nsp1-40S complex, composite map 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M.L, Thiel, V, Muehlemann, O, Ban, N. 登録日 2020-07-07 公開日 2020-07-22 最終更新日 2021-02-10 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
6ZVH	EDF1-ribosome complex 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Best, K.M, Denk, T, Cheng, J, Thoms, M, Berninghausen, O, Beckmann, R. 登録日 2020-07-24 公開日 2020-08-19 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 EDF1 coordinates cellular responses to ribosome collisions. Elife, 9, 2020
3GML	Structure of mouse CD1d in complex with C6Ph 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ... 著者 Schiefner, A, Wilson, I.A. 登録日 2009-03-14 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
4IRJ	Structure of the mouse CD1d-4ClPhC-alpha-GalCer-iNKT TCR complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... 著者 Nemcovic, M, Zajonc, D.M. 登録日 2013-01-14 公開日 2013-08-28 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Enhanced TCR footprint by a novel glycolipid increases NKT-dependent tumor protection. J.Immunol., 191, 2013
7K5I	SARS-COV-2 nsp1 in complex with human 40S ribosome 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Wang, L, Shi, M, Wu, H. 登録日 2020-09-16 公開日 2020-10-14 最終更新日 2021-03-17 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism. Biorxiv, 2020
4IRS	Structure of the mouse CD1d-PyrC-alpha-GalCer-iNKT TCR complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nemcovic, M, Zajonc, D.M. 登録日 2013-01-15 公開日 2013-09-04 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Enhanced TCR footprint by a novel glycolipid increases NKT-dependent tumor protection. J.Immunol., 191, 2013
3GMQ	Structure of mouse CD1d expressed in SF9 cells, no ligand added 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ... 著者 Schiefner, A, Wilson, I.A. 登録日 2009-03-14 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
3GMO	Structure of mouse CD1d in complex with C8PhF 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-(4-fluorophenyl)-N-{(1S,2S,3R)-1-[(alpha-D-galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl}octanamide, ... 著者 Schiefner, A, Wilson, I.A. 登録日 2009-03-14 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
3GMR	Structure of mouse CD1d in complex with C8Ph, different space group 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ... 著者 Schiefner, A, Wilson, I.A. 登録日 2009-03-14 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
3GMM	Structure of mouse CD1d in complex with C8Ph 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ... 著者 Schiefner, A, Wilson, I.A. 登録日 2009-03-14 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
3GMP	Structure of mouse CD1d in complex with PBS-25 分子名称: (2S,3S,4R)-N-OCTANOYL-1-[(ALPHA-D-GALACTOPYRANOSYL)OXY]-2-AMINO-OCTADECANE-3,4-DIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Schiefner, A, Wilson, I.A. 登録日 2009-03-14 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
3GMN	Structure of mouse CD1d in complex with C10Ph 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2 microglobulin, ... 著者 Schiefner, A, Wilson, I.A. 登録日 2009-03-14 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. J.Mol.Biol., 394, 2009
3LGH	Crystal structure of NikR from Helicobacter pylori with variable Ni site coordination 分子名称: MAGNESIUM ION, NICKEL (II) ION, nickel-responsive regulator 著者 Pozharski, E, St John, F. 登録日 2010-01-20 公開日 2010-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Holo-Ni(II)HpNikR Is an Asymmetric Tetramer Containing Two Different Nickel-Binding Sites. J.Am.Chem.Soc., 132, 2010
8ABY	RNA polymerase bound to purified in vitro transcribed regulatory RNA putL - pause prone, closed clamp state 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Dey, S, Weixlbaumer, A. 登録日 2022-07-05 公開日 2022-10-19 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural insights into RNA-mediated transcription regulation in bacteria. Mol.Cell, 82, 2022
8AC0	RNA polymerase at U-rich pause bound to regulatory RNA putL - active, closed clamp state 分子名称: DNA Non-template strand, DNA Template strand, DNA-directed RNA polymerase subunit alpha, ... 著者 Weixlbaumer, A, Dey, S. 登録日 2022-07-05 公開日 2022-10-19 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural insights into RNA-mediated transcription regulation in bacteria. Mol.Cell, 82, 2022
8ACP	RNA polymerase at U-rich pause bound to regulatory RNA putL - inactive, open clamp state 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Dey, S, Weixlbaumer, A. 登録日 2022-07-06 公開日 2022-10-19 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural insights into RNA-mediated transcription regulation in bacteria. Mol.Cell, 82, 2022

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