PDB: 1466 件ウェブページステータス検索Chemie searchBIRD

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6A42	R1EN(5-223)-ubiquitin fusion 分子名称: ACETIC ACID, RNA-directed DNA polymerase homolog (R1),Polyubiquitin-C 著者 Maita, N. 登録日 2018-06-19 公開日 2018-10-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure Determination of Ubiquitin by Fusion to a Protein That Forms a Highly Porous Crystal Lattice J. Am. Chem. Soc., 140, 2018
5VZM	Solution NMR structure of human Rev1 (932-1039) in complex with ubiquitin 分子名称: DNA repair protein REV1, Ubiquitin 著者 Cui, G, Botuyan, M.V, Mer, G. 登録日 2017-05-29 公開日 2018-05-23 最終更新日 2019-12-04 実験手法 SOLUTION NMR 主引用文献 Structural Basis for the Interaction of Mutasome Assembly Factor REV1 with Ubiquitin. J. Mol. Biol., 430, 2018
5WQ4	Crystal structure of OPTN and linear diubiquitin complex 分子名称: Optineurin, ubiquitin 著者 Li, F, Pan, L. 登録日 2016-11-23 公開日 2017-12-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation. Autophagy, 14, 2018
5TL7	Crystal structure of SARS-CoV papain-like protease in complex with C-terminal domain mouse ISG15 分子名称: Replicase polyprotein 1ab, Ubiquitin-like protein ISG15, ZINC ION 著者 Daczkowski, C.D, Dzimianski, J.V, Pegan, S.D. 登録日 2016-10-10 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species. J. Mol. Biol., 429, 2017
5WVO	Crystal structure of DNMT1 RFTS domain in complex with K18/K23 mono-ubiquitylated histone H3 分子名称: DNA (cytosine-5)-methyltransferase 1, Histone H3.1, Ubiquitin, ... 著者 Ishiyama, S, Nishiyama, A, Nakanishi, M, Arita, K. 登録日 2016-12-28 公開日 2017-11-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.997 Å) 主引用文献 Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance Mol. Cell, 68, 2017
3V62	Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164 分子名称: ATP-dependent DNA helicase SRS2, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ... 著者 Armstrong, A.A, Mohideen, F, Lima, C.D. 登録日 2011-12-18 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature, 483, 2012
3VAW	Crystal structure of a smt fusion peptidyl-prolyl cis-trans isomerase with surface mutation v3i from burkholderia pseudomallei complexed with fk506 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, Ubiquitin-like protein SMT3,Peptidyl-prolyl cis-trans isomerase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-12-29 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
3VUW	Crystal structure of A20 ZF7 in complex with linear ubiquitin, form I 分子名称: POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2012-07-09 公開日 2013-02-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
3VUX	Crystal structure of A20 ZF7 in complex with linear ubiquitin, form II 分子名称: 1,2-ETHANEDIOL, POTASSIUM ION, Polyubiquitin-C, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2012-07-09 公開日 2013-02-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
3WXG	Crystal structure of CYLD USP domain (C596A) in complex with Lys63-linked diubiquitin 分子名称: Ubiquitin, Uncharacterized protein 著者 Sato, Y, Fukai, S. 登録日 2014-07-30 公開日 2015-02-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity. Nat.Struct.Mol.Biol., 22, 2015
3WXE	Crystal structure of CYLD USP domain (C596S) in complex with Met1-linked diubiquitin 分子名称: Ubiquitin, Uncharacterized protein 著者 Sato, Y, Fukai, S. 登録日 2014-07-30 公開日 2015-02-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity. Nat.Struct.Mol.Biol., 22, 2015
3ZNH	Crimean Congo Hemorrhagic Fever Virus OTU domain in complex with ubiquitin-propargyl. 分子名称: POLYUBIQUITIN-B, UBIQUITIN THIOESTERASE 著者 Ekkebus, R, vanKasteren, S.I, Kulathu, Y, Scholten, A, Berlin, I, deJong, A, Goerdayal, G, Neefjes, J, Heck, A.J.R, Komander, D, Ovaa, H. 登録日 2013-02-14 公開日 2013-02-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 On Terminal Alkynes that Can React with Active-Site Cysteine Nucleophiles in Proteases. J.Am.Chem.Soc., 135, 2013
3ZTC	pVHL54-213-EloB-EloC complex _ (2S,4R)-N-((1,1'-biphenyl)-4-ylmethyl)- 4-hydroxy-1-(2-(3-methylisoxazol-5-yl)acetyl)pyrrolidine-2- carboxamide 分子名称: (4R)-N-(BIPHENYL-4-YLMETHYL)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-L-PROLINAMIDE, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, ... 著者 Van Molle, I, Buckley, D.L, Crews, C.M, Ciulli, A. 登録日 2011-07-06 公開日 2012-07-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Dissecting Fragment-Based Lead Discovery at the Von Hippel-Lindau Protein:Hypoxia Inducible Factor 1Alpha Protein-Protein Interface. Chem.Biol., 19, 2012
3ZRC	pVHL54-213-EloB-EloC complex (4R)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-N-[4-(1,3-OXAZOL-5-YL)BENZYL]-L-PROLINAMIDE bound 分子名称: (4R)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-N-[4-(1,3-OXAZOL-5-YL)BENZYL]-L-PROLINAMIDE, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, ... 著者 Van Molle, I, Buckley, D.L, Crews, C.M, Ciulli, A. 登録日 2011-06-15 公開日 2012-03-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Targeting the Von Hippel-Lindau E3 Ubiquitin Ligase Using Small Molecules to Disrupt the Vhl/Hif-1Alpha Interaction J.Am.Chem.Soc., 134, 2012
3ZDM	Crystal structure of the Sgt2 N domain and the Get5 UBL domain complex 分子名称: SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT- CONTAINING PROTEIN 2, UBIQUITIN-LIKE PROTEIN MDY2 著者 Tung, J.-Y, Li, Y.-C, Hsiao, C.-D. 登録日 2012-11-29 公開日 2013-10-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.803 Å) 主引用文献 Structure of the Sgt2 Dimerization Domain Complexed with the Get5 Ubl Domain Involved in the Targeting of Tail-Anchored Membrane Proteins to the Endoplasmic Reticulum. Acta Crystallogr.,Sect.D, 69, 2013
3ZUN	pVHL54-213-EloB-EloC complex_(2S,4R)-4-hydroxy-1-(2-(3-methylisoxazol- 5-yl)acetyl)-N-(4-nitrobenzyl)pyrrolidine-2-carboxamide bound 分子名称: (4R)-N-[4-(DIHYDROXYAMINO)BENZYL]-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-L-PROLINAMIDE, GLYCEROL, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... 著者 Van Molle, I, Buckley, D, Crews, C.M, Ciulli, A. 登録日 2011-07-19 公開日 2012-07-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Elongin-B, Elongin-C, Von Hippel-Lindau Disease Tumor Suppressor Complex To be Published
3ZKJ	Crystal Structure of Ankyrin Repeat and Socs Box-Containing Protein 9 (Asb9) in Complex with Elonginb and Elonginc 分子名称: 1,2-ETHANEDIOL, ANKYRIN REPEAT AND SOCS BOX PROTEIN 9, CHLORIDE ION, ... 著者 Muniz, J.R.C, Guo, K, Zhang, Y, Ayinampudi, V, Savitsky, P, Keates, T, Filippakopoulos, P, Vollmar, M, Yue, W.W, Krojer, T, Ugochukwu, E, von Delft, F, Knapp, S, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. 登録日 2013-01-23 公開日 2013-01-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases J.Mol.Biol., 425, 2013
3ZNG	Ankyrin repeat and SOCS-box protein 9 (ASB9) in complex with ElonginB and ElonginC 分子名称: 1,2-ETHANEDIOL, ANKYRIN REPEAT AND SOCS BOX PROTEIN 9, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... 著者 Thomas, J, Van Molle, I, Ciulli, A. 登録日 2013-02-14 公開日 2013-12-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Multimeric Complexes Among Ankyrin-Repeat and Socs-Box Protein 9 (Asb9), Elonginbc, and Cullin 5: Insights Into the Structure and Assembly of Ecs-Type Cullin-Ring E3 Ubiquitin Ligases. Biochemistry, 52, 2013
3ZRF	pVHL54-213-EloB-EloC complex_apo 分子名称: TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR, 著者 Van Molle, I, Buckley, D.L, Crews, C.M, Ciulli, A. 登録日 2011-06-16 公開日 2012-03-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Targeting the Von Hippel-Lindau E3 Ubiquitin Ligase Using Small Molecules to Disrupt the Vhl/Hif-1Alpha Interaction J.Am.Chem.Soc., 134, 2012
3ZNZ	Crystal structure of OTULIN OTU domain (C129A) in complex with Met1- di ubiquitin 分子名称: POLYUBIQUITIN-C, PROTEIN FAM105B, SULFATE ION 著者 Keusekotten, K, Elliott, P.R, Glockner, L, Kulathu, Y, Wauer, T, Krappmann, D, Hofmann, K, Komander, D. 登録日 2013-02-18 公開日 2013-06-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin. Cell(Cambridge,Mass.), 153, 2013
3WXF	Crystal structure of CYLD USP domain (C596S E674Q) in complex with Met1-linked diubiquitin 分子名称: SULFATE ION, Ubiquitin, Uncharacterized protein 著者 Sato, Y, Fukai, S. 登録日 2014-07-30 公開日 2015-02-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity. Nat.Struct.Mol.Biol., 22, 2015
3ZTD	pVHL54-213-EloB-EloC complex _ methyl 4-(((2S,4R)-4-hydroxy-1-(2-(3- methylisoxazol-5-yl)acetyl)pyrrolidine-2-carboxamido)methyl)benzoate 分子名称: METHYL 4-[({(4R)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-L-PROLYL}AMINO)METHYL]BENZOATE, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, ... 著者 VanMolle, I, Buckley, D.L, Crews, C.M, Ciulli, A. 登録日 2011-07-07 公開日 2012-07-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Dissecting Fragment-Based Lead Discovery at the Von Hippel-Lindau Protein:Hypoxia Inducible Factor 1Alpha Protein-Protein Interface. Chem.Biol., 19, 2012
3UQA	Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation A54E from Burkholderia pseudomallei complexed with FK506 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-11-19 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
4AJY	von Hippel-Lindau protein-ElonginB-ElonginC complex, bound to Hif1- alpha peptide 分子名称: GLYCEROL, HYPOXIA-INDUCIBLE FACTOR 1-ALPHA, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... 著者 Van Molle, I, Thomann, A, Buckley, D.L, So, E.C, Lang, S, Crews, C.M, Ciulli, A. 登録日 2012-02-21 公開日 2012-11-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Dissecting Fragment-Based Lead Discovery at the Von Hippel-Lindau Protein:Hypoxia Inducible Factor 1Alpha Protein-Protein Interface. Chem.Biol., 19, 2012
3V6E	Crystal Structure of USP2 and a mutant form of Ubiquitin 分子名称: CHLORIDE ION, GLYCEROL, Ubiquitin, ... 著者 Neculai, M, Ernst, A, Sidhu, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2011-12-19 公開日 2012-12-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013

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