3DXE
 
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3H33
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3H34
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2MJN
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2MAL
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2MSR
 | | Solution structure of LEDGF/p75 IBD in complex with MLL1 peptide (140-160) | | 分子名称: | Histone-lysine N-methyltransferase 2A, PC4 and SFRS1-interacting protein | | 著者 | Cermakova, K, Tesina, P, Demeulemeester, J, El Ashkar, S, Mereau, H, Schwaller, J, Rezacova, P, Veverka, V, De Rijck, J. | | 登録日 | 2014-08-05 | | 公開日 | 2014-08-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Validation and Structural Characterization of the LEDGF/p75-MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia.
Cancer Res., 74, 2014
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2MTN
 | | Solution structure of MLL-IBD complex | | 分子名称: | Histone-lysine N-methyltransferase 2A, PC4 and SFRS1-interacting protein fusion | | 著者 | Cierpicki, T, Pollock, J, Murai, M. | | 登録日 | 2014-08-23 | | 公開日 | 2014-12-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIV.
Blood, 124, 2014
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2MYG
 | | Solution structure of the dithiolic glutaredoxin 2-C-Grx1 from the pathogen Trypanosoma brucei brucei | | 分子名称: | Dithiol glutaredoxin 1 | | 著者 | Sturlese, M, Stefani, M, Manta, B, Mammi, S, Comini, M, Bellanda, M. | | 登録日 | 2015-01-22 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the dithiolic glutaredoxin 2-C-Grx1 from the pathogen Trypanosoma brucei brucei
To be Published
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2MXN
 | | NMR Structure of the mature form of Trypanosoma brucei 1CGrx1 | | 分子名称: | Mono-cysteine glutaredoxin | | 著者 | Sturlese, M, Bertarello, A, Manta, B, Lelli, M, Mammi, S, Comini, M, Bellanda, M. | | 登録日 | 2015-01-08 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The lineage-specific, intrinsically disordered N-terminal extension of monothiol glutaredoxin 1 from trypanosomes contains a regulatory region.
Sci Rep, 8, 2018
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2N81
 | | Solution Structure of Lipid Transfer Protein From Pea Pisum Sativum | | 分子名称: | Lipid Transfer Protein | | 著者 | Paramonov, A.S, Rumynskiy, E.I, Bogdanov, I.V, Finkina, E.I, Melnikova, D.N, Ovchinnikova, T.V, Shenkarev, Z.O, Arseniev, A.S. | | 登録日 | 2015-09-30 | | 公開日 | 2016-05-11 | | 最終更新日 | 2017-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A novel lipid transfer protein from the pea Pisum sativum: isolation, recombinant expression, solution structure, antifungal activity, lipid binding, and allergenic properties.
BMC Plant Biol, 16
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2MZ0
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2NVK
 | | Crystal Structure of Thioredoxin Reductase from Drosophila melanogaster | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin Reductase | | 著者 | Eckenroth, B.E, Rould, M.A, Hondal, R.J, Everse, S.J. | | 登録日 | 2006-11-13 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and Biochemical Studies Reveal Differences in the Catalytic Mechanisms of Mammalian and Drosophila melanogaster Thioredoxin Reductases.
Biochemistry, 46, 2007
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2N88
 | | Chromodomain 3 (CD3) of cpSRP43 | | 分子名称: | Signal recognition particle 43 kDa protein, chloroplastic | | 著者 | Hennig, J, Sattler, M. | | 登録日 | 2015-10-06 | | 公開日 | 2015-12-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction.
Nat Commun, 6, 2015
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5VT3
 | | High resolution structure of thioredoxin-disulfide reductase from Vibrio vulnificus CMCP6 in complex with NADP and FAD | | 分子名称: | CACODYLATE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Chang, C, Grimshaw, S, Maltseva, N, Mulligan, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2017-05-15 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | High resolution structure of thioredoxin-disulfide reductase from Vibrio vulnificus CMCP6 in complex with NADP and FAD
To Be Published
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2RA4
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2JYI
 | | Solution structure of MLL CXXC domain | | 分子名称: | ZINC ION, Zinc finger protein HRX | | 著者 | Cierpicki, T, Bushweller, J.H. | | 登録日 | 2007-12-13 | | 公開日 | 2008-12-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for maintenance of unmethylated CpG elements by the CXXC domain of MLL and its critical contributions to MLL-AF9 immortalization activity
To be Published
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8B4L
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2KKF
 | | Solution structure of MLL CXXC domain in complex with palindromic CPG DNA | | 分子名称: | 5'-D(*CP*CP*CP*TP*GP*CP*GP*CP*AP*GP*GP*G)-3', Histone-lysine N-methyltransferase HRX, ZINC ION | | 著者 | Cierpicki, T, Riesbeck, J.E, Grembecka, J.E, Lukasik, S.M, Popovic, R, Omonkowska, M, Shultis, D.S, Zeleznik-Le, N.J, Bushweller, J.H. | | 登録日 | 2009-06-18 | | 公開日 | 2009-12-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia.
Nat.Struct.Mol.Biol., 17, 2010
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2KYU
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2LXS
 | | Allosteric communication in the KIX domain proceeds through dynamic re-packing of the hydrophobic core | | 分子名称: | CREB-binding protein, Histone-lysine N-methyltransferase MLL | | 著者 | Bruschweiler, S, Schanda, P, Konrat, R, Tollinger, M. | | 登録日 | 2012-08-31 | | 公開日 | 2013-06-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Allosteric communication in the KIX domain proceeds through dynamic repacking of the hydrophobic core.
Acs Chem.Biol., 8, 2013
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7RFP
 | | Mouse GITR (mGITR) with DTA-1 Fab fragment | | 分子名称: | DTA-1 (heavy chain), DTA-1 (light chain), Tumor necrosis factor receptor superfamily member 18,Enhanced green fluorescent protein | | 著者 | Meyerson, J.R, He, C. | | 登録日 | 2021-07-14 | | 公開日 | 2022-03-09 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Therapeutic antibody activation of the glucocorticoid-induced TNF receptor by a clustering mechanism.
Sci Adv, 8, 2022
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7E8D
 | | NSD2 E1099K mutant bound to nucleosome | | 分子名称: | DNA (185-MER), Histone H2A type 1, Histone H2B type 1-J, ... | | 著者 | Sengoku, T, Sato, K, Nishizawa, T, Nureki, O, Ogata, K. | | 登録日 | 2021-03-01 | | 公開日 | 2021-11-10 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2.
Nat Commun, 12, 2021
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5JU7
 | | DNA BINDING DOMAIN OF E.COLI CADC | | 分子名称: | Transcriptional activator CadC, ZINC ION | | 著者 | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | | 登録日 | 2016-05-10 | | 公開日 | 2017-04-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator.
Sci Rep, 7, 2017
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6D1O
 | | FT_5 dioxygenase apoenzyme | | 分子名称: | (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase | | 著者 | Rydel, T.J, Halls, C.E. | | 登録日 | 2018-04-12 | | 公開日 | 2018-08-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops.
Pest Manag. Sci., 75, 2019
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6BWT
 | | 2.45 Angstrom Resolution Crystal Structure Thioredoxin Reductase from Francisella tularensis. | | 分子名称: | CHLORIDE ION, SULFATE ION, Thioredoxin reductase | | 著者 | Minasov, G, Shuvalova, L, Dubrovska, I, Winsor, J, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2017-12-15 | | 公開日 | 2017-12-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | 2.45 Angstrom Resolution Crystal Structure Thioredoxin Reductase from Francisella tularensis.
To Be Published
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