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2MTN

Solution structure of MLL-IBD complex

Summary for 2MTN
Entry DOI10.2210/pdb2mtn/pdb
NMR InformationBMRB: 25171
DescriptorHistone-lysine N-methyltransferase 2A, PC4 and SFRS1-interacting protein fusion (1 entity in total)
Functional Keywordsprotein-protein complex, transferase-protein binding complex, transferase/protein binding
Biological sourceHomo sapiens (human)
Cellular locationNucleus : O75475
Total number of polymer chains1
Total formula weight18208.90
Authors
Cierpicki, T.,Pollock, J.,Murai, M. (deposition date: 2014-08-23, release date: 2014-12-03, Last modification date: 2015-04-22)
Primary citationMurai, M.J.,Pollock, J.,He, S.,Miao, H.,Purohit, T.,Yokom, A.,Hess, J.L.,Muntean, A.G.,Grembecka, J.,Cierpicki, T.
The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIV.
Blood, 124:3730-3737, 2014
Cited by
PubMed: 25305204
DOI: 10.1182/blood-2014-01-550079
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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