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2MTN

Solution structure of MLL-IBD complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHistone-lysine N-methyltransferase 2A, PC4 and SFRS1-interacting protein fusionpolymer16418208.91UniProt (Q03164)
UniProt (O75475)
Pfam (PF11467)
In PDB
Homo sapiens (human)Lysine N-methyltransferase 2A, ALL-1, CXXC-type zinc finger protein 7, Myeloid/lymphoid or mixed-lineage leukemia, Myeloid/lymphoid or mixed-lineage leukemia protein 1, Trithorax-like protein, Zinc finger protein HRX, MLL cleavage product N320, N-terminal cleavage product of 320 kDa, p320, MLL cleavage product C180, C-terminal cleavage product of 180 kDa, p180, CLL-associated antigen KW-7, Dense fine speckles 70 kDa protein, DFS 70, Lens epithelium-derived growth factor, Transcriptional coactivator p75/p52
Sequence modifications
A: 110 - 334 (UniProt: Q03164)
PDBExternal DatabaseDetails
Gly 105-expression tag
Pro 106-expression tag
Ala 107-expression tag
Met 108-expression tag
Ala 109-expression tag
Gly 335-linker
Ser 336-linker
A: 337 - 442 (UniProt: O75475)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18208.9
All*Total formula weight18208.9
*Water molecules are not included.

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PDB entries from 2024-07-17

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