3V3R
| Crystal Structure of GES-11 | 分子名称: | Extended spectrum class A beta-lactamase GES-11, IODIDE ION, SODIUM ION | 著者 | Delbruck, H, Hoffmann, K.M.V, Bebrone, C. | 登録日 | 2011-12-14 | 公開日 | 2012-09-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | 主引用文献 | Kinetic and crystallographic studies of extended-spectrum GES-11, GES-12, and GES-14 beta-lactamases. Antimicrob.Agents Chemother., 56, 2012
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3TSG
| Crystal structure of GES-14 | 分子名称: | Extended-spectrum beta-lactamase GES-14, GLYCEROL, IODIDE ION | 著者 | Delbruck, H, Hoffmann, K.M.V, Bebrone, C. | 登録日 | 2011-09-13 | 公開日 | 2012-09-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Kinetic and crystallographic studies of extended-spectrum GES-11, GES-12, and GES-14 beta-lactamases. Antimicrob.Agents Chemother., 56, 2012
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3TOI
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3TG9
| The crystal structure of penicillin binding protein from Bacillus halodurans | 分子名称: | Penicillin-binding protein | 著者 | Zhang, Z, Satyanarayana, L, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, LaFleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2011-08-17 | 公開日 | 2011-08-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structure of penicillin binding protein from Bacillus halodurans To be Published
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3SOI
| Crystallographic structure of Bacillus licheniformis beta-lactamase W210F/W229F/W251F at 1.73 angstrom resolution | 分子名称: | Beta-lactamase, CITRIC ACID | 著者 | Acierno, J.P, Capaldi, S, Risso, V.A, Monaco, H.L, Ermacora, M.R. | 登録日 | 2011-06-30 | 公開日 | 2011-12-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.729 Å) | 主引用文献 | X-ray evidence of a native state with increased compactness populated by tryptophan-less B. licheniformis beta-lactamase. Protein Sci., 21, 2012
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3SH9
| Crystal structure of fluorophore-labeled beta-lactamase PenP in complex with cefotaxime | 分子名称: | 1-[6-(dimethylamino)naphthalen-2-yl]ethanone, Beta-lactamase, CEFOTAXIME, ... | 著者 | Wong, W.-T, Zhao, Y.-X, Leung, Y.-C. | 登録日 | 2011-06-16 | 公開日 | 2011-07-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Increased structural flexibility at the active site of a fluorophore-conjugated beta-lactamase distinctively impacts its binding toward diverse cephalosporin antibiotics J.Biol.Chem., 286, 2011
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3SH8
| Crystal structure of fluorophore-labeled beta-lactamase PenP in complex with cephaloridine | 分子名称: | 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase | 著者 | Wong, W.-T, Zhao, Y.-X, Leung, Y.-C. | 登録日 | 2011-06-16 | 公開日 | 2011-07-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Increased structural flexibility at the active site of a fluorophore-conjugated beta-lactamase distinctively impacts its binding toward diverse cephalosporin antibiotics J.Biol.Chem., 286, 2011
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3SH7
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3S4X
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3S22
| AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA) in complex with an inhibitor | 分子名称: | Beta-lactamase, CHLORIDE ION, [(2S,3R)-2-formyl-1-{[4-(methylamino)butyl]carbamoyl}pyrrolidin-3-yl]sulfamic acid | 著者 | Scapin, G, Lu, J, Fitzgerald, P.M.D, Sharma, N. | 登録日 | 2011-05-16 | 公開日 | 2011-06-29 | 最終更新日 | 2013-06-26 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Side chain SAR of bicyclic Beta-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712 Bioorg.Med.Chem.Lett., 21, 2011
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3S1Y
| AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA) in complex with a beta-lactamase inhibitor | 分子名称: | Beta-lactamase, CHLORIDE ION, ISOPROPYL ALCOHOL, ... | 著者 | Scapin, G, Lu, J, Fitzgerald, P.M.D, Sharma, N. | 登録日 | 2011-05-16 | 公開日 | 2011-06-29 | 最終更新日 | 2013-06-26 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Side chain SAR of bicyclic Beta-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712 Bioorg.Med.Chem.Lett., 21, 2011
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3RXX
| KPC-2 carbapenemase in complex with 3-NPBA | 分子名称: | 3-NITROPHENYLBORONIC ACID, Carbepenem-hydrolyzing beta-lactamase KPC | 著者 | Ke, W, van den Akker, F. | 登録日 | 2011-05-10 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Crystal structures of KPC-2 {beta}-lactamase in complex with 3-nitrophenyl boronic acid and the penam sulfone PSR-3-226. Antimicrob.Agents Chemother., 56, 2012
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3RXW
| KPC-2 carbapenemase in complex with PSR3-226 | 分子名称: | (2S,3R)-4-(2-amino-2-oxoethoxy)-3-(dihydroxy-lambda~4~-sulfanyl)-3-methyl-4-oxo-2-{[(1E)-3-oxoprop-1-en-1-yl]amino}butanoic acid, CITRIC ACID, Carbepenem-hydrolyzing beta-lactamase KPC | 著者 | Ke, W, van den Akker, F. | 登録日 | 2011-05-10 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Crystal structures of KPC-2 {beta}-lactamase in complex with 3-nitrophenyl boronic acid and the penam sulfone PSR-3-226. Antimicrob.Agents Chemother., 56, 2012
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3RJU
| Crystal Structure of Beta-lactamase/D-alanine Carboxypeptidase from Yersinia pestis complexed with citrate | 分子名称: | Beta-lactamase/D-alanine Carboxypeptidase, CITRIC ACID, GLYCEROL | 著者 | Kim, Y, Zhou, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2011-04-15 | 公開日 | 2011-04-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structure of Beta-lactamase/D-alanine Carboxypeptidase from Yersinia pestis complexed with citrate To be Published
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3QHY
| Structural, thermodynamic and kinetic analysis of the picomolar binding affinity interaction of the beta-lactamase inhibitor protein-II (BLIP-II) with class A beta-lactamases | 分子名称: | Beta-lactamase, Beta-lactamase inhibitory protein II | 著者 | Brown, N.G, Chow, D.C, Sankaran, B, Zwart, P, Prasad, B.V.V, Palzkill, T, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2011-01-26 | 公開日 | 2011-07-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Analysis of the binding forces driving the tight interactions between beta-lactamase inhibitory protein-II (BLIP-II) and class A beta-lactamases. J.Biol.Chem., 286, 2011
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3Q1F
| CTX-M-9 S70G in complex with hydrolyzed piperacillin | 分子名称: | Beta-lactamase, Hydrolyzed piperacillin | 著者 | Leyssne, D, Delmas, J, Coignoux, A, Robin, F, Bonnet, R. | 登録日 | 2010-12-17 | 公開日 | 2011-12-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | CTX-M-9 S70G mutant in complex with hydrolyzed piperacillin To be Published
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3Q07
| CTX-M-9 S70G in complex with piperacillin | 分子名称: | Beta-lactamase, Hydrolyzed piperacillin, Piperacillin | 著者 | Delmas, J, Leyssne, D, Robin, F, Coignoux, A, Bonnet, R. | 登録日 | 2010-12-15 | 公開日 | 2011-12-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | CTX-M-9 S70G mutant in complex with piperacillin To be Published
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3PTE
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3P98
| The crystal structure of the extended spectrum beta-lactamase TEM-72 reveals inhibition by citrate | 分子名称: | Beta-lactamase TEM-72, CITRIC ACID, DI(HYDROXYETHYL)ETHER | 著者 | Docquier, J.D, Benvenuti, M, Calderone, V, Rossolini, G.M, Mangani, S. | 登録日 | 2010-10-16 | 公開日 | 2011-03-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the extended-spectrum [beta]-lactamase TEM-72 inhibited by citrate Acta Crystallogr.,Sect.F, 67, 2011
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3OZH
| Crystal Structure of Beta-Lactamase/D-alanine Carboxypeptidase from Yersinia pestis | 分子名称: | beta-lactamase/D-alanine carboxypeptidase | 著者 | Kim, Y, Zhou, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-09-24 | 公開日 | 2010-10-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.907 Å) | 主引用文献 | Crystal Structure of Beta-Lactamase/D-alanine Carboxypeptidase from Yersinia pestis To be Published
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3OPR
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3OPP
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3OPL
| ESBL R164H mutant SHV-1 beta-lactamase | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE | 著者 | Sampson, J.M, van den Akker, F. | 登録日 | 2010-09-01 | 公開日 | 2011-07-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Ligand-dependent disorder of the Omega loop observed in extended-spectrum SHV-type beta-lactamase. Antimicrob.Agents Chemother., 55, 2011
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3OPH
| ESBL R164S mutant of SHV-1 beta-lactamase | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE | 著者 | Sampson, J.M, van den Akker, F. | 登録日 | 2010-09-01 | 公開日 | 2011-07-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Ligand-dependent disorder of the Omega loop observed in extended-spectrum SHV-type beta-lactamase. Antimicrob.Agents Chemother., 55, 2011
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3O88
| Crystal structure of AmpC beta-lactamase in complex with a sulfonamide boronic acid inhibitor | 分子名称: | 3-[(2R)-2-[(benzylsulfonyl)amino]-2-(dihydroxyboranyl)ethyl]benzoic acid, Beta-lactamase, PHOSPHATE ION | 著者 | Eidam, O, Romagnoli, C, Karpiak, J, Shoichet, B.K. | 登録日 | 2010-08-02 | 公開日 | 2010-11-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Design, Synthesis, Crystal Structures, and Antimicrobial Activity of Sulfonamide Boronic Acids as beta-Lactamase Inhibitors J.Med.Chem., 53, 2010
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