3OPL

ESBL R164H mutant SHV-1 beta-lactamase

Summary for 3OPL

• Entry DOI: 10.2210/pdb3opl/pdb
• Related: 1SHV 2H5S 3OPH 3OPP 3OPR
• Descriptor: Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
• Functional Keywords: class a beta-lactamase, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 32496.45

Authors

Sampson, J.M.,van den Akker, F. (deposition date: 2010-09-01, release date: 2011-07-13, Last modification date: 2023-09-06)

• Primary citation: Sampson, J.M.,Ke, W.,Bethel, C.R.,Pagadala, S.R.,Nottingham, M.D.,Bonomo, R.A.,Buynak, J.D.,van den Akker, F.; Ligand-dependent disorder of the Omega loop observed in extended-spectrum SHV-type beta-lactamase.; Antimicrob.Agents Chemother., 55:2303-2309, 2011; PubMed: 21357298; DOI: 10.1128/AAC.01360-10

Experimental method

X-RAY DIFFRACTION (1.8 Å)